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Dive into the research topics where John Isaacs is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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AKT Inhibition Sensitizes to Polo-Like Kinase 1 Inhibitor Onvansertib in Prostate Cancer
Nouri, M., Varkaris, A., Ridinger, M., Dalrymple, S. L., Dennehy, C. M., Isaacs, J. T., Einstein, D. J., Brennen, W. N. & Balk, S. P., Oct 2024, In: Molecular cancer therapeutics. 23, 10, p. 1404-1417 14 p.Research output: Contribution to journal › Article › peer-review
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Characterization of structural, biochemical, pharmacokinetic, and pharmacodynamic properties of the LSD1 inhibitor bomedemstat in preclinical models
Jasmine, S., Mandl, A., Krueger, T. E. G., Dalrymple, S. L., Antony, L., Dias, J., Celatka, C. A., Tapper, A. E., Kleppe, M., Kanayama, M., Jing, Y., Speranzini, V., Wang, Y. Z., Luo, J., Trock, B. J., Denmeade, S. R., Carducci, M. A., Mattevi, A., Rienhoff, H. Y. & Isaacs, J. T. & 1 others, , Jul 2024, In: Prostate. 84, 10, p. 909-921 13 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Targeting the fibroblast growth factor pathway in molecular subtypes of castration-resistant prostate cancer
Labrecque, M. P., Brown, L. G., Coleman, I. M., Nguyen, H. M., Dalrymple, S., Brennen, W. N., Isaacs, J. T., Li, D., Lakely, B., DeLucia, D. C., Lee, J. K., Schweizer, M. T., Lin, D. W., Corey, E., Nelson, P. S. & Morrissey, C., Jan 2024, In: Prostate. 84, 1, p. 100-110 11 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Plk1 Inhibitors and Abiraterone Synergistically Disrupt Mitosis and Kill Cancer Cells of Disparate Origin Independently of Androgen Receptor Signaling
Patterson, J. C., Varkaris, A., Croucher, P. J. P., Ridinger, M., Dalrymple, S., Nouri, M., Xie, F., Varmeh, S., Jonas, O., Whitman, M. A., Chen, S., Rashed, S., Makusha, L., Luo, J., Isaacs, J. T., Erlander, M. G., Einstein, D. J., Balk, S. P. & Yaffe, M. B., Jan 15 2023, In: Cancer Research. 83, 2, p. 219-238 20 p.Research output: Contribution to journal › Article › peer-review
Open Access -
The future of patient-derived xenografts in prostate cancer research
Lawrence, M. G., Taylor, R. A., Cuffe, G. B., Ang, L. S., Clark, A. K., Goode, D. L., Porter, L. H., Le Magnen, C., Navone, N. M., Schalken, J. A., Wang, Y., van Weerden, W. M., Corey, E., Isaacs, J. T., Nelson, P. S. & Risbridger, G. P., Jun 2023, In: Nature Reviews Urology. 20, 6, p. 371-384 14 p.Research output: Contribution to journal › Article › peer-review
Open Access