Research output per year
Research output per year
- 1 - 50 out of 154 results
Search results
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2022
HMGA1 chromatin regulators induce transcriptional networks involved in GATA2 and proliferation during MPN progression
Li, L., Kim, J. H., Lu, W., Williams, D. M., Kim, J., Cope, L., Rampal, R. K., Koche, R. P., Xian, L., Luo, L. Z., Vasiljevic, M., Matson, D. R., Zhao, Z. J., Rogers, O., Stubbs, M. C., Reddy, K., Romero, A. R., Psaila, B., Spivak, J. L., Moliterno, A. R., & 1 others, May 5 2022, In: Blood. 139, 18, p. 2797-2815 19 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2020
Sex determines the presentation and outcomes in MPN and is related to sex-specific differences in the mutational burden
Karantanos, T., Chaturvedi, S., Braunstein, E. M., Spivak, J., Resar, L., Karanika, S., Williams, D. M., Rogers, O., Gocke, C. D. & Moliterno, A. R., Jun 23 2020, In: Blood Advances. 4, 12, p. 2567-2576 10 p.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
Thrombopoietin is required for full phenotype expression in a JAK2V617F transgenic mouse model of polycythemia vera
Spivak, J. L., Merchant, A., Williams, D. M., Rogers, O., Zhao, W., Duffield, A., Resar, L. S., Moliterno, A. R. & Zhao, Z. J., Jun 2020, In: PloS one. 15, 6, e0232801.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
2019
How I treat polycythemia vera
Spivak, J. L., Jul 25 2019, In: Blood. 134, 4, p. 341-352 12 p.Research output: Contribution to journal › Article › peer-review
Open Access20 Scopus citations -
2017
Generation of human iPSCs from an essential thrombocythemia patient carrying a V501L mutation in the MPL gene
Liu, S., Ye, Z., Gao, Y., He, C., Williams, D. W., Moliterno, A., Spivak, J., Huang, H. & Cheng, L., Jan 2017, In: Stem Cell Research. 18, p. 57-59 3 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Multicenter analysis of the use of transjugular intrahepatic portosystemic shunt for management of MPN-associated portal hypertension
Reilly, C. R., Babushok, D. V., Martin, K., Spivak, J. L., Streiff, M., Bahirwani, R., Mondschein, J., Stein, B., Moliterno, A. & Hexner, E. O., Sep 2017, In: American journal of hematology. 92, 9, p. 909-914 6 p.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
2016
Practice Patterns in the Diagnosis andTreatment of Polycythemia Vera in the Post-JAK2 V617F Discovery Era
Kander, E. M., Moliterno, A. R., Rademaker, A., Streiff, M. B., Spivak, J. L. & Stein, B. L., Oct 1 2016, In: JNCCN Journal of the National Comprehensive Cancer Network. 14, 10, p. 1238-1245 8 p.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
Ruxolitinib enhances platelet production in patients with thrombocytopenic myelofibrosis
Grunwald, M. R. & Spivak, J. L., Feb 10 2016, In: Journal of Clinical Oncology. 34, 5, p. e38-e40Research output: Contribution to journal › Article › peer-review
10 Scopus citations -
2014
Differential sensitivity to jak inhibitory drugs by isogenic human erythroblasts and hematopoietic progenitors generated from patient-specific induced pluripotent stem cells
Ye, Z., Liu, C. F., Lanikova, L., Dowey, S. N., He, C., Huang, X., Brodsky, R. A., Spivak, J. L., Prchal, J. T. & Cheng, L., Jan 2014, In: Stem Cells. 32, 1, p. 269-278 10 p.Research output: Contribution to journal › Article › peer-review
Open Access27 Scopus citations -
Two clinical phenotypes in polycythemia vera
Spivak, J. L., Considine, M., Williams, D. M., Talbot, C. C., Rogers, O., Moliterno, A. R., Jie, C. & Ochs, M. F., Aug 28 2014, In: New England Journal of Medicine. 371, 9, p. 808-817 10 p.Research output: Contribution to journal › Article › peer-review
Open Access34 Scopus citations -
2013
Age-related differences in disease characteristics and clinical outcomes in polycythemia vera
Stein, B. L., Saraf, S., Sobol, U., Halpern, A., Shammo, J., Rondelli, D., Michaelis, L., Odenike, O., Rademaker, A., Zakarija, A., McMahon, B., Spivak, J. L. & Moliterno, A. R., Sep 2013, In: Leukemia and Lymphoma. 54, 9, p. 1989-1995 7 p.Research output: Contribution to journal › Article › peer-review
43 Scopus citations -
Could hypoxia increase the prevalence of thrombotic complications in polycythemia vera?
Zangari, M., Fink, L., Tolomelli, G., Lee, J. C. H., Stein, B. L., Hickman, K., Swierczek, S., Kelley, T. W., Berno, T., Moliterno, A. R., Spivak, J. L., Gordeuk, V. R. & Prchal, J. T., Apr 2013, In: Blood Coagulation and Fibrinolysis. 24, 3, p. 311-316 6 p.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
MicroRNA deregulation in polycythemia vera and essential thrombocythemia patients
Zhan, H., Cardozo, C., Yu, W., Wang, A., Moliterno, A. R., Dang, C. V. & Spivak, J. L., Mar 2013, In: Blood Cells, Molecules, and Diseases. 50, 3, p. 190-195 6 p.Research output: Contribution to journal › Article › peer-review
Open Access18 Scopus citations -
Update in hematology and oncology: Evidence published in 2012
Eads, J. R., Meropol, N. J. & Spivak, J. L., May 21 2013, In: Annals of internal medicine. 158, 10, p. 755-760 6 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
2012
Treatment of polycythemia vera with imatinib mesylate
Silver, R. T., Bourla, M. H., Vandris, K., Fruchtman, S., Spivak, J. L., Feldman, E. J. & Salvado, A. J., Feb 2012, In: Leukemia Research. 36, 2, p. 156-162 7 p.Research output: Contribution to journal › Article › peer-review
12 Scopus citations -
2011
Disease burden at the progenitor level is a feature of primary myelofibrosis: A multivariable analysis of 164 JAK2 V617F-positive myeloproliferative neoplasm patients
Stein, B. L., Williams, D. M., Rogers, O., Isaacs, M. A., Spivak, J. L. & Moliterno, A. R., Jan 2011, In: Experimental Hematology. 39, 1, p. 95-101 7 p.Research output: Contribution to journal › Article › peer-review
Open Access29 Scopus citations -
Disruption of the ASXL1 gene is frequent in primary, post-essential thrombocytosis and post-polycythemia vera myelofibrosis, but not essential thrombocytosis or polycythemia vera: Analysis of molecular genetics and clinical phenotypes
Stein, B. L., Williams, D. M., O'Keefe, C., Rogers, O., Ingersoll, R. G., Spivak, J. L., Verma, A., Maciejewski, J. P., McDevitt, M. A. & Moliterno, A. R., Oct 2011, In: Haematologica. 96, 10, p. 1462-1469 8 p.Research output: Contribution to journal › Article › peer-review
Open Access65 Scopus citations -
Iron and the anemia of chronic disease: vindication for the non-essential role of iron supplementation.
Spivak, J. L., Apr 30 2011, In: Oncology. 25, 5, p. 421-423 3 p.Research output: Contribution to journal › Article › peer-review
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2010
Sex differences in the JAK2V617F allele burden in chronic myeloproliferative disorders
Stein, B. L., Williams, D. M., Wang, N. Y., Rogers, O., Isaacs, M. A., Pemmaraju, N., Spivak, J. L. & Moliterno, A. R., Jul 2010, In: Haematologica. 95, 7, p. 1090-1096 7 p.Research output: Contribution to journal › Article › peer-review
Open Access57 Scopus citations -
2009
Human-induced pluripotent stem cells from blood cells of healthy donors and patients with acquired blood disorders
Ye, Z., Zhan, H., Mali, P., Dowey, S., Williams, D. M., Jang, Y. Y., Dang, C. V., Spivak, J. L., Moliterno, A. R. & Cheng, L., Dec 24 2009, In: Blood. 114, 27, p. 5473-5480 8 p.Research output: Contribution to journal › Article › peer-review
Open Access290 Scopus citations -
2008
Phenotypic variability within the JAK2 V617F-positive MPD: Roles of progenitor cell and neutrophil allele burdens
Moliterno, A. R., Williams, D. M., Rogers, O., Isaacs, M. A. & Spivak, J. L., Nov 2008, In: Experimental Hematology. 36, 11, p. 1480-1486.e2Research output: Contribution to journal › Article › peer-review
Open Access59 Scopus citations -
The revised world health organization diagnostic criteria for polycythemia vera, essential thrombocytosis, and primary myelofibrosis: An alternative proposal
Spivak, J. L. & Silver, R. T., Jul 15 2008, In: Blood. 112, 2, p. 231-239 9 p.Research output: Contribution to journal › Article › peer-review
Open Access133 Scopus citations -
2007
Phenotype and genotype in the myeloproliferative disorders
Spivak, J. L., Oct 2007, In: European Journal of Haematology. 79, SUPPL. 68, p. 9-12 4 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Phenotypic variations and new mutations in JAK2 V617F-negative polycythemia vera, erythrocytosis, and idiopathic myelofibrosis
Williams, D. M., Kim, A. H., Rogers, O., Spivak, J. L. & Moliterno, A. R., Nov 2007, In: Experimental Hematology. 35, 11, p. 1641-1646 6 p.Research output: Contribution to journal › Article › peer-review
Open Access69 Scopus citations -
The Third International Congress on Myeloproliferative and Myelodysplastic Syndromes
Silver, R. T., Bennett, J. M., Goldman, J. M., Spivak, J. L. & Tefferi, A., Jan 2007, In: Leukemia Research. 31, 1, p. 11-17 7 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
2006
Molecular mimicry in the chronic myeloproliferative disorders: Reciprocity between quantitative JAK2 V617F and Mp1 expression
Moliterno, A. R., Williams, D. M., Rogers, O. & Spivak, J. L., Dec 1 2006, In: Blood. 108, 12, p. 3913-3915 3 p.Research output: Contribution to journal › Article › peer-review
Open Access81 Scopus citations -
2005
A case of pulmonary hypertension associated with a rare congenital hemolytic anemia
Sukkar, A., Mollura, D. J., King, K. E., Spivak, J. L., Hassoun, P. M. & McDyer, J. F., Sep 2005, In: Clinical Pulmonary Medicine. 12, 5, p. 319-322 4 p.Research output: Contribution to journal › Article › peer-review
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Allogeneic hematopoietic stem-cell transplantation with reduced-intensity conditioning in intermediate- or high-risk patients with myelofibrosis with myeloid metaplasia
Rondelli, D., Barosi, G., Bacigalupo, A., Prchal, J. T., Popat, U., Alessandrino, E. P., Spivak, J. L., Douglas Smith, B., Klingemann, H. G., Fruchtman, S. & Hoffman, R., May 15 2005, In: Blood. 105, 10, p. 4115-4119 5 p.Research output: Contribution to journal › Article › peer-review
Open Access177 Scopus citations -
Detection, evaluation, and management of anemia in the elective surgical patient
Goodnough, L. T., Shander, A., Spivak, J. L., Waters, J. H., Friedman, A. J., Carson, J. L., Keating, E. M., Maddox, T. & Spence, R., Dec 2005, In: Anesthesia and analgesia. 101, 6, p. 1858-1861 4 p.Research output: Contribution to journal › Article › peer-review
Open Access111 Scopus citations -
Polycythemia vera: Scientific advances and current practice
Tefferi, A. & Spivak, J. L., Oct 2005, In: Seminars in Hematology. 42, 4, p. 206-220 15 p.Research output: Contribution to journal › Article › peer-review
58 Scopus citations -
Thrombotic and bleeding complications in four subpopulations of patients with essential thrombocythemia defined by C-Mpl protein expression and PRV-1 mRNA levels
Goerttler, P. S., März, E., Johansson, P. L., Andreasson, B., Kutti, J., Moliterno, A. R., Marchioli, R., Spivak, J. L. & Pahl, H. L., Jun 2005, In: Haematologica. 90, 6, p. 851-853 3 p.Research output: Contribution to journal › Article › peer-review
12 Scopus citations -
2004
59-Year-old woman with anemia resulting from breast-cancer therapy
Spivak, J. L., Apr 1 2004, In: Advanced Studies in Medicine. 4, 3 B, p. S201Research output: Contribution to journal › Article › peer-review
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Models of granulocyte DNA structure are highly predictive of myelodysplastic syndrome
Malins, D. C., Anderson, K. M., Polissar, N. L., Ostrander, G. K., Knobbe, E. T., Green, V. M., Gilman, N. K. & Spivak, J. L., Apr 6 2004, In: Proceedings of the National Academy of Sciences of the United States of America. 101, 14, p. 5008-5011 4 p.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
Mpl Baltimore: A thrombopoietin receptor polymorphism associated with thrombocytosis
Moliterno, A. R., Williams, D. M., Gutierrez-Alamillo, L. I., Salvatori, R., Ingersoll, R. G. & Spivak, J. L., Aug 3 2004, In: Proceedings of the National Academy of Sciences of the United States of America. 101, 31, p. 11444-11447 4 p.Research output: Contribution to journal › Article › peer-review
Open Access93 Scopus citations -
The chronic myeloproliferative disorders: Clonality and clinical heterogeneity
Spivak, J. L., Apr 2004, In: Seminars in Hematology. 41, 2 SUPPL. 3, p. 1-5 5 p.Research output: Contribution to journal › Article › peer-review
92 Scopus citations -
The second international congress on myeloproliferative and myelodysplastic syndromes
Silver, R. T., Bennett, J. M., Deininger, M., Feldman, E., Rafii, S., Silverstein, R. L., Solberg, L. A. & Spivak, J. L., Sep 2004, In: Leukemia Research. 28, 9, p. 979-985 7 p.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
2003
Diagnosis of the myeloproliferative disorders: Resolving phenotypic mimicry
Spivak, J. L., Jan 2003, In: Seminars in Hematology. 40, 1 SUPPL. 1, p. 1-5 5 p.Research output: Contribution to journal › Article › peer-review
21 Scopus citations -
Maxwell Wintrobe, in his own words.
Spivak, J. L., Apr 2003, In: British journal of haematology. 121, 2, p. 224-232 9 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
2002
The diagnosis and management of polycythemia vera in the era since the Polycythemia Vera Study Group: A survey of american society of hematology members' practice patterns
Streiff, M. B., Smith, B. & Spivak, J. L., Feb 15 2002, In: Blood. 99, 4, p. 1144-1149 6 p.Research output: Contribution to journal › Article › peer-review
Open Access87 Scopus citations -
2001
A mail survey of United States hematologists and oncologists: A comparison of business reply versus stamped return envelopes
Streiff, M. B., Dundes, L. & Spivak, J. L., 2001, In: Journal of Clinical Epidemiology. 54, 4, p. 430-432 3 p.Research output: Contribution to journal › Article › peer-review
Open Access25 Scopus citations -
Erythropoietin use and abuse: When physiology and pharmacology collide
Spivak, J. L., Dec 1 2001, In: Advances in experimental medicine and biology. 502, p. 207-224 18 p.Research output: Contribution to journal › Article › peer-review
34 Scopus citations -
2000
Chairman's introduction
Spivak, J. L., Dec 1 2000, In: Medical Oncology. 17, SUPPL. 1, p. S1Research output: Contribution to journal › Article › peer-review
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Current thinking and treatment practices in anaemia - An interactive poll
Spivak, J. L. & Cazzola, M., Dec 1 2000, In: Medical Oncology. 17, SUPPL. 1, p. S32-S37Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
1999
Posttranslational processing of the thrombopoietin receptor is impaired in polycythemia vera
Moliterno, A. R. & Spivak, J. L., Oct 15 1999, In: Blood. 94, 8, p. 2555-2561 7 p.Research output: Contribution to journal › Article › peer-review
78 Scopus citations -
1998
A novel thrombopoietin signaling defect in polycythemia vera platelets.
Moliterno, A. R., Siebel, K. E., Sun, A. Y., Hankins, W. D. & Spivak, J. L., 1998, In: Stem cells (Dayton, Ohio). 16 Suppl 2, p. 185-192 8 p.Research output: Contribution to journal › Article › peer-review
Open Access18 Scopus citations -
Immunoablative high-dose cyclophosphamide without stem-cell rescue for refractory, severe autoimmune disease
Brodsky, R. A., Petri, M., Smith, B. D., Seifter, E. J., Spivak, J. L., Styler, M., Dang, C. V., Brodsky, I. & Jones, R. J., Dec 15 1998, In: Annals of internal medicine. 129, 12, p. 1031-1035 5 p.Research output: Contribution to journal › Article › peer-review
202 Scopus citations -
Impaired expression of the thrombopoietin receptor by platelets from patients with polycythemia vera
Moliterno, A. R., David Hankins, W. & Spivak, J. L., Feb 26 1998, In: New England Journal of Medicine. 338, 9, p. 572-580 9 p.Research output: Contribution to journal › Article › peer-review
Open Access244 Scopus citations -
1996
Anemia of cancer
Moliterno, A. R. & Spivak, J. L., 1996, In: Hematology/Oncology Clinics of North America. 10, 2, p. 345-362 18 p.Research output: Contribution to journal › Article › peer-review
Open Access57 Scopus citations -
Cell cycle-specific behavior of erythropoietin
Spivak, J. L., Ferris, D. K., Fisher, J., Noga, S. J., Isaacs, M., Connor, E. & Hankins, W. D., 1996, In: Experimental Hematology. 24, 2, p. 141-150 10 p.Research output: Contribution to journal › Article › peer-review
10 Scopus citations -
Isolation of the full-length murine erythropoietin receptor using a baculovirus expression system
Spivak, J. L., Avedissian, L. S., Pierce, J. H., Williams, D., Hankins, W. D. & Jensen, R. A., Feb 1 1996, In: Blood. 87, 3, p. 926-937 12 p.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations