Research output per year
Research output per year
- 50 - 100 out of 185 results
Search results
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Article
Determinants of Visual Pigment Absorbance: Identification of the Retinylidene Schiff's Base Counterion in Bovine Rhodopsin
Nathans, J., Oct 1 1990, In: Biochemistry. 29, 41, p. 9746-9752 7 p.Research output: Contribution to journal › Article › peer-review
306 Scopus citations -
Determinants of Visual Pigment Absorbance: Role of Charged Amino Acids in the Putative Transmembrane Segments
Nathans, J., Jan 1 1990, In: Biochemistry. 29, 4, p. 937-942 6 p.Research output: Contribution to journal › Article › peer-review
176 Scopus citations -
Developmental, cellular, and behavioral phenotypes in a mouse model of congenital hypoplasia of the dentate gyrus
Rattner, A., Terrillion, C. E., Jou, C., Kleven, T., Hu, S. F., Williams, J., Hou, Z., Aggarwal, M., Mori, S., Shin, G., Goff, L. A., Witter, M. P., Pletnikov, M., Fenton, A. A. & Nathans, J., Oct 2020, In: eLife. 9, p. 1-30 30 p., e62766.Research output: Contribution to journal › Article › peer-review
Open Access -
Distinct Roles of Transcription Factors Brn3a and Brn3b in Controlling the Development, Morphology, and Function of Retinal Ganglion Cells
Badea, T. C., Cahill, H., Ecker, J., Hattar, S. & Nathans, J., Mar 26 2009, In: Neuron. 61, 6, p. 852-864 13 p.Research output: Contribution to journal › Article › peer-review
Open Access170 Scopus citations -
Dlg1 activates beta-catenin signaling to regulate retinal angiogenesis and the blood-retina and blood-brain barriers
Cho, C., Wang, Y., Smallwood, P. M., Williams, J. & Nathans, J., May 2019, In: eLife. 8, e45542.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Effects of L1 retrotransposon insertion on transcript processing, localization and accumulation: Lessons from the retinal degeneration 7 mouse and implications for the genomic ecology of L1 elements
Chen, J., Rattner, A. & Nathans, J., Jul 2006, In: Human molecular genetics. 15, 13, p. 2146-2156 11 p.Research output: Contribution to journal › Article › peer-review
51 Scopus citations -
Emergence of novel color vision in mice engineered to express a human cone photopigment
Jacobs, G. H., Williams, G. A., Cahill, H. & Nathans, J., Mar 23 2007, In: Science. 315, 5819, p. 1723-1725 3 p.Research output: Contribution to journal › Article › peer-review
141 Scopus citations -
Endothelial microRNA-150 is an intrinsic suppressor of pathologic ocular neovascularization
Liu, C. H., Sun, Y., Li, J., Gong, Y., Tian, K. T., Evans, L. P., Morss, P. C., Fredrick, T. W., Saba, N. J., Chen, J. & Nathans, J., Sep 29 2015, In: Proceedings of the National Academy of Sciences of the United States of America. 112, 39, p. 12163-12168 6 p.Research output: Contribution to journal › Article › peer-review
55 Scopus citations -
Endothelin-2 signaling in the neural retina promotes the endothelial tip cell state and inhibits angiogenesis
Rattner, A., Yu, H., Williams, J., Smallwood, P. M. & Nathans, J., Oct 1 2013, In: Proceedings of the National Academy of Sciences of the United States of America. 110, 40, p. E3830-E3839Research output: Contribution to journal › Article › peer-review
Open Access24 Scopus citations -
Epigenomic landscapes of retinal rods and cones
Mo, A., Luo, C., Davis, F. P., Mukamel, E. A., Henry, G. L., Nery, J. R., Urich, M. A., Picard, S., Lister, R., Eddy, S. R., Beer, M. A., Ecker, J. R. & Nathans, J., Mar 7 2016, In: eLife. 5, MARCH2016, e11613.Research output: Contribution to journal › Article › peer-review
Open Access68 Scopus citations -
Epigenomic Signatures of Neuronal Diversity in the Mammalian Brain
Mo, A., Mukamel, E. A., Davis, F. P., Luo, C., Henry, G. L., Picard, S., Urich, M. A., Nery, J. R., Sejnowski, T. J., Lister, R., Eddy, S. R., Ecker, J. R. & Nathans, J., Jun 17 2015, In: Neuron. 86, 6, p. 1369-1384 16 p.Research output: Contribution to journal › Article › peer-review
Open Access294 Scopus citations -
Essential role of POU-domain factor Brn-3c in auditory and vestibular hair cell development
Xiang, M., Gan, L., Li, D., Chen, Z. Y., Zhou, L., O'Malley, B. W., Klein, W. & Nathans, J., Aug 19 1997, In: Proceedings of the National Academy of Sciences of the United States of America. 94, 17, p. 9445-9450 6 p.Research output: Contribution to journal › Article › peer-review
Open Access237 Scopus citations -
Estrogen-Related Receptor β/NR3B2 Controls Epithelial Cell Fate and Endolymph Production by the Stria Vascularis
Chen, J. & Nathans, J., Sep 4 2007, In: Developmental Cell. 13, 3, p. 325-337 13 p.Research output: Contribution to journal › Article › peer-review
Open Access87 Scopus citations -
Expression and regulation of chicken fibroblast growth factor homologous factor (FHF)-4 at the base of the developing limbs
Muñoz-Sanjuán, I., Fallon, J. F. & Nathans, J., Jul 1 2000, In: Mechanisms of Development. 95, 1-2, p. 101-112 12 p.Research output: Contribution to journal › Article › peer-review
Open Access13 Scopus citations -
Expression and regulation of chicken fibroblast growth factor homologous factor (FHF)-4 during craniofacial morphogenesis
Muñoz-Sanjuán, I., Cooper, M. K., Beachy, P. A., Fallon, J. F. & Nathans, J., 2001, In: Developmental Dynamics. 220, 3, p. 238-245 8 p.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
Expression of chicken fibroblast growth factor homologous factor (FHF)-1 and of differentially spliced isoforms of FHF-2 during development and involvement of FHF-2 in chicken limb development
Munoz-Sanjuan, I., Simandl, B. K., Fallon, J. F. & Nathans, J., Jan 1999, In: Development. 126, 2, p. 409-421 13 p.Research output: Contribution to journal › Article › peer-review
42 Scopus citations -
Expression of the Norrie disease gene (Ndp) in developing and adult mouse eye, ear, and brain
Ye, X., Smallwood, P. & Nathans, J., Jan 2011, In: Gene Expression Patterns. 11, 1-2, p. 151-155 5 p.Research output: Contribution to journal › Article › peer-review
36 Scopus citations -
Fibroblast growth factor (FGF) homologous factors: New members of the FGF family implicated in nervous system development
Smallwood, P. M., Munoz-Sanjuan, I., Tong, P., Macke, J. P., Hendry, S. H. C., Gilbert, D. J., Copeland, N. G., Jenkins, N. A. & Nathans, J., Sep 3 1996, In: Proceedings of the National Academy of Sciences of the United States of America. 93, 18, p. 9850-9857 8 p.Research output: Contribution to journal › Article › peer-review
Open Access312 Scopus citations -
Flat mount imaging of mouse skin and its application to the analysis of hair follicle patterning and sensory axon morphology
Chang, H., Wang, Y., Wu, H. & Nathans, J., Jun 25 2014, In: Journal of Visualized Experiments. 88, e51749.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
Four novel mutations in the RPE65 gene in patients with Leber congenital amaurosis.
Simovich, M. J., Miller, B., Ezzeldin, H., Kirkland, B. T., McLeod, G., Fulmer, C., Nathans, J., Jacobson, S. G. & Pittler, S. J., Aug 2001, In: Human mutation. 18, 2, p. 164 1 p.Research output: Contribution to journal › Article › peer-review
Open Access42 Scopus citations -
Frizzled 1 and frizzled 2 genes function in palate, ventricular septum and neural tube closure: General implications for tissue fusion processes
Yu, H., Smallwood, P. M., Wang, Y., Vidaltamayo, R., Reed, R. & Nathans, J., Nov 1 2010, In: Development. 137, 21, p. 3707-3717 11 p.Research output: Contribution to journal › Article › peer-review
Open Access89 Scopus citations -
Frizzled 2 and frizzled 7 function redundantly in convergent extension and closure of the ventricular septum and palate: Evidence for a network of interacting genes
Yu, H., Ye, X., Guo, N. & Nathans, J., Dec 1 2012, In: Development (Cambridge). 139, 23, p. 4383-4394 12 p.Research output: Contribution to journal › Article › peer-review
Open Access90 Scopus citations -
Frizzled3 controls axonal development in distinct populations of cranial and spinal motor neurons
Hua, Z. L., Smallwood, P. M. & Nathans, J., Dec 17 2013, In: eLife. 2013, 2, e01482.Research output: Contribution to journal › Article › peer-review
Open Access33 Scopus citations -
Frizzled-3 is required for the development of major fiber tracts in the rostral CNS
Wang, Y., Thekdi, N., Smallwood, P. M., Macke, J. P. & Nathans, J., Oct 1 2002, In: Journal of Neuroscience. 22, 19, p. 8563-8573 11 p.Research output: Contribution to journal › Article › peer-review
Open Access223 Scopus citations -
Frizzled3 is required for the development of multiple axon tracts in the mouse central nervous system
Hua, Z. L., Jeon, S., Caterina, M. J. & Nathans, J., Jul 22 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 29, p. E3005-E3014Research output: Contribution to journal › Article › peer-review
Open Access37 Scopus citations -
Frizzled6 controls hair patterning in mice
Guo, N., Hawkins, C. & Nathans, J., Jun 22 2004, In: Proceedings of the National Academy of Sciences of the United States of America. 101, 25, p. 9277-9281 5 p.Research output: Contribution to journal › Article › peer-review
Open Access222 Scopus citations -
Frizzled and DFrizzled-9 function as redundant receptors for wingless during Drosophila embryonic development
Bhanot, P., Fish, M., Jemison, J. A., Nusse, R., Nathans, J. & Cadigan, K. M., Sep 1999, In: Development. 126, 18, p. 4175-4186 12 p.Research output: Contribution to journal › Article › peer-review
133 Scopus citations -
Functional Assembly of Accessory Optic System Circuitry Critical for Compensatory Eye Movements
Sun, L. O., Brady, C. M., Cahill, H., Al-Khindi, T., Sakuta, H., Dhande, O. S., Noda, M., Huberman, A. D., Nathans, J. & Kolodkin, A. L., May 20 2015, In: Neuron. 86, 4, p. 971-984 14 p.Research output: Contribution to journal › Article › peer-review
Open Access46 Scopus citations -
Functional heterogeneity of mutant rhodopsins responsible for autosomal dominant retinitis pigmentosa
Sung, C. H., Schneider, B. G., Agarwal, N., Papermaster, D. S. & Nathans, J., Oct 1 1991, In: Proceedings of the National Academy of Sciences of the United States of America. 88, 19, p. 8840-8844 5 p.Research output: Contribution to journal › Article › peer-review
388 Scopus citations -
Ganglion cell response properties in the coneless retina of a transgenic mouse
Soucy, E. R., Wang, Y., Nathans, J. & Meister, M., Feb 15 1996, In: Investigative Ophthalmology and Visual Science. 37, 3, p. S1057Research output: Contribution to journal › Article › peer-review
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Genetic ablation of cone photoreceptors eliminates retinal folds in the retinal degeneration 7 (rd7) mouse
Chen, J. & Nathans, J., Jun 2007, In: Investigative Ophthalmology and Visual Science. 48, 6, p. 2799-2805 7 p.Research output: Contribution to journal › Article › peer-review
27 Scopus citations -
Genetically-directed, cell type-specific sparse labeling for the analysis of neuronal morphology
Rotolo, T., Smallwood, P. M., Williams, J. & Nathans, J., Dec 31 2008, In: PloS one. 3, 12, e4099.Research output: Contribution to journal › Article › peer-review
Open Access45 Scopus citations -
Genetically engineered mice with an additional class of cone photoreceptors: Implications for the evolution of color vision
Smallwood, P. M., Ölveczky, B. P., Williams, G. L., Jacobs, G. H., Reese, B. E., Meister, M. & Nathans, J., Sep 30 2003, In: Proceedings of the National Academy of Sciences of the United States of America. 100, 20, p. 11706-11711 6 p.Research output: Contribution to journal › Article › peer-review
74 Scopus citations -
Genetic heterogeneity among blue-cone monochromats
Nathans, J., Maumenee, I. H., Zrenner, E., Sadowski, B., Sharpe, L. T., Lewis, R. A., Hansen, E., Rosenberg, T., Schwartz, M., Heckenlively, J. R., Traboulsi, E., Klingaman, R., Bech-Hansen, N. T., LaRoche, G. R., Pagon, R. A., Murphey, W. H. & Weleber, R. G., Nov 1993, In: American journal of human genetics. 53, 5, p. 987-1000 14 p.Research output: Contribution to journal › Article › peer-review
117 Scopus citations -
Genetic mosaic analysis reveals a major role for frizzled 4 and frizzled 8 in controlling ureteric growth in the developing kidney
Ye, X., Wang, Y., Rattner, A. & Nathans, J., Mar 2011, In: Development. 138, 6, p. 1161-1172 12 p.Research output: Contribution to journal › Article › peer-review
43 Scopus citations -
Gpr124 controls CNS angiogenesis and blood-brain barrier integrity by promoting ligand-specific canonical Wnt signaling
Zhou, Y. & Nathans, J., Oct 27 2014, In: Developmental Cell. 31, 2, p. 248-256 9 p.Research output: Contribution to journal › Article › peer-review
Open Access123 Scopus citations -
Histidine residues regulate the transition of photoexcited rhodopsin to its active conformation, metarhodopsin II
Weitz, C. J. & Nathans, J., Mar 1992, In: Neuron. 8, 3, p. 465-472 8 p.Research output: Contribution to journal › Article › peer-review
72 Scopus citations -
How scientists can reduce their carbon footprint
Nathans, J. & Sterling, P., Mar 31 2016, In: eLife. 5, MARCH2016, e15928.Research output: Contribution to journal › Article › peer-review
Open Access18 Scopus citations -
How to draw the line in biomedical research
Huang, L., Rattner, A., Liu, H. & Nathans, J., Mar 19 2013, In: eLife. 2013, 2, e00638.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Human rod photoreceptor cGMP-gated channel: Amino acid sequence, gene structure, and functional expression
Dhallan, R. S., Macke, J. P., Eddy, R. L., Shows, T. B., Reed, R. R., Yau, K. W. & Nathans, J., 1992, In: Journal of Neuroscience. 12, 8, p. 3248-3256 9 p.Research output: Contribution to journal › Article › peer-review
Open Access99 Scopus citations -
Human tritanopia associated with two amino acid substitutions in the blue- sensitive opsin
Weitz, C. J., Miyake, Y., Shinzato, K., Montag, E., Zrenner, E., Went, L. N. & Nathans, J., 1992, In: American journal of human genetics. 50, 3, p. 498-507 10 p.Research output: Contribution to journal › Article › peer-review
87 Scopus citations -
Hypoxia tolerance in the Norrin-deficient retina and the chronically hypoxic brain studied at single-cell resolution
Heng, J. S., Rattner, A., Stein-O’Brien, G. L., Winer, B. L., Jones, B. W., Vernon, H. J., Goff, L. A. & Nathans, J., Apr 30 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 18, p. 9103-9114 12 p.Research output: Contribution to journal › Article › peer-review
Open Access17 Scopus citations -
Identification and characterization of a conserved family of protein serine/threonine phosphatases homologous to Drosophila retinal degeneration C (rdgC)
Sherman, P. M., Sun, H., Macke, J. P., Williams, J., Smallwood, P. M. & Nathans, J., Oct 14 1997, In: Proceedings of the National Academy of Sciences of the United States of America. 94, 21, p. 11639-11644 6 p.Research output: Contribution to journal › Article › peer-review
Open Access47 Scopus citations -
Identification and characterization of all-trans-retinol dehydrogenase from photoreceptor outer segments, the visual cycle enzyme that reduces all- trans-retinal to all-trans-retinol
Rattner, A., Smallwood, P. M. & Nathans, J., Apr 14 2000, In: Journal of Biological Chemistry. 275, 15, p. 11034-11043 10 p.Research output: Contribution to journal › Article › peer-review
Open Access162 Scopus citations -
Identification of Astrotactin2 as a Genetic Modifier That Regulates the Global Orientation of Mammalian Hair Follicles
Chang, H., Cahill, H., Smallwood, P. M., Wang, Y. & Nathans, J., 2015, In: PLoS genetics. 11, 9, e1005532.Research output: Contribution to journal › Article › peer-review
Open Access13 Scopus citations -
Identification of novel rhodopsin mutations responsible for retinitis pigmentosa: implications for the structure and function of rhodopsin
Macke, J. P., Davenport, C. M., Jacobson, S. G., Hennessey, J. C., Gonzalez-Fernandez, F., Conway, B. P., Heckenlively, J., Palmer, R., Maumenee, I. H., Sieving, P., Gouras, P., Good, W. & Nathans, J., Jul 1993, In: American journal of human genetics. 53, 1, p. 80-89 10 p.Research output: Contribution to journal › Article › peer-review
93 Scopus citations -
Individual variation in the size of the human red and green visual pigment gene array
Macke, J. P. & Nathans, J., 1997, In: Investigative Ophthalmology and Visual Science. 38, 5, p. 1040-1043 4 p.Research output: Contribution to journal › Article › peer-review
31 Scopus citations -
Insertional mutagenesis as a probe of rhodopsin's topography, stability, and activity
Borjigin, J. & Nathans, J., May 20 1994, In: Journal of Biological Chemistry. 269, 20, p. 14715-14722 8 p.Research output: Contribution to journal › Article › peer-review
69 Scopus citations -
Insights into Wnt binding and signalling from the structures of two Frizzled cysteine-rich domains
Dann, C. E., Hsieh, J. C., Rattner, A., Sharma, D., Nathans, J. & Leahy, D. J., Jul 5 2001, In: Nature. 412, 6842, p. 86-90 5 p.Research output: Contribution to journal › Article › peer-review
343 Scopus citations -
Interplay of the Norrin and Wnt7a/Wnt7b signaling systems in blood–brain barrier and blood–retina barrier development and maintenance
Wang, Y., Cho, C., Williams, J., Smallwood, P. M., Zhang, C., Junge, H. J. & Nathans, J., Dec 11 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 50, p. E11827-E11836Research output: Contribution to journal › Article › peer-review
Open Access43 Scopus citations