Jennifer Leiding

2025

Azithromycin for Critically Ill Children With Bronchiolitis: A U.S. Pediatric Health Information Systems Registry Study, 2013-2022

Roberts, A. R., Vallabhaneni, N., Russi, B. W., Delaney, K. M., Leiding, J. W. & Sochet, A. A., 2025, (Accepted/In press) In: Pediatric Critical Care Medicine. 10.1097/PCC.0000000000003724.

Research output: Contribution to journal › Article › peer-review

Emapalumab Treatment in Patients With Rheumatologic Disease–Associated Hemophagocytic Lymphohistiocytosis in the United States: A Retrospective Medical Chart Review Study

the REAL-HLH Investigators, Feb 2025, In: Arthritis and Rheumatology. 77, 2, p. 226-238 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Inborn errors of immunity reveal molecular requirements for generation and maintenance of human CD4⁺ IL-9–expressing cells

Rao, G., Mack, C. D., Nguyen, T., Wong, N., Payne, K., Worley, L., Gray, P. E., Wong, M., Hsu, P., Stormon, M. O., Preece, K., Suan, D., O'Sullivan, M., Blincoe, A. K., Sinclair, J., Okada, S., Hambleton, S., Arkwright, P. D., Boztug, K. & Stepensky, P. & 18 others, Cooper, M. A., Bezrodnik, L., Nadeau, K. C., Abolhassani, H., Abraham, R. S., Seppänen, M. R. J., Béziat, V., Bustamante, J., Forbes Satter, L. R., Leiding, J. W., Meyts, I., Jouanguy, E., Boisson-Dupuis, S., Uzel, G., Puel, A., Casanova, J. L., Tangye, S. G. & Ma, C. S., Apr 2025, In: Journal of Allergy and Clinical Immunology. 155, 4, p. 1161-1178 18 p.

Research output: Contribution to journal › Article › peer-review

Multiomics dissection of human RAG deficiency reveals distinctive patterns of immune dysregulation but a common inflammatory signature

Centralized Sequencing Program Group, Jan 2025, In: Science Immunology. 10, 103, eadq1697.

Research output: Contribution to journal › Article › peer-review

2024

Allogeneic hematopoietic cell transplantation is effective for p47phox chronic granulomatous disease: A Primary Immune Deficiency Treatment Consortium study

Grunebaum, E., Arnold, D. E., Logan, B., Parikh, S., Marsh, R. A., Griffith, L. M., Mallhi, K., Chellapandian, D., Lim, S. S., Deal, C. L., Kapoor, N., Murguía-Favela, L., Falcone, E. L., Prasad, V. K., Touzot, F., Bleesing, J. J., Chandrakasan, S., Heimall, J. R., Bednarski, J. J. & Broglie, L. A. & 21 others, Chong, H. J., Kapadia, M., Prockop, S., Dávila Saldaña, B. J., Schaefer, E., Bauchat, A. L., Teira, P., Chandra, S., Parta, M., Cowan, M. J., Dvorak, C. C., Haddad, E., Kohn, D. B., Notarangelo, L. D., Pai, S. Y., Puck, J. M., Pulsipher, M. A., Torgerson, T. R., Malech, H. L., Kang, E. M. & Leiding, J. W., May 2024, In: Journal of Allergy and Clinical Immunology. 153, 5, p. 1423-1431.e2

Research output: Contribution to journal › Article › peer-review

Azithromycin for Pediatric Critical Asthma: A Multicenter Retrospective Cohort Study

Roberts, A. R., Vallabhaneni, N., Russi, B., Spence, T. L., Leiding, J. W. & Sochet, A. A., May 2024, In: Hospital Pediatrics. 14, 6, p. e254-e259

Research output: Contribution to journal › Article › peer-review

Bacterial sepsis triggers stronger transcriptomic immune responses in larger primates

McMinds, R., Jiang, R. H. Y., Adapa, S. R., Cornelius Ruhs, E., Munds, R. A., Leiding, J. W., Downs, C. J. & Martin, L. B., Jun 26 2024, In: Proceedings of the Royal Society B: Biological Sciences. 291, 2025, 20240535.

Research output: Contribution to journal › Article › peer-review

Clinical and functional spectrum of RAC2-related immunodeficiency

Donkó, Á., Sharapova, S. O., Kabat, J., Ganesan, S., Hauck, F. H., Bergerson, J. R. E., Marois, L., Abbott, J., Moshous, D., Williams, K. W., Campbell, N., Martin, P. L., Lagresle-Peyrou, C., Trojan, T., Kuzmenko, N. B., Deordieva, E. A., Raykina, E. V., Abers, M. S., Abolhassani, H. & Barlogis, V. & 27 others, Milla, C., Hall, G., Mousallem, T., Church, J., Kapoor, N., Cros, G., Chapdelaine, H., Franco-Jarava, C., Lopez-Lerma, I., Miano, M., Leiding, J. W., Klein, C., Stasia, M. J., Fischer, A., Hsiao, K. C., Martelius, T., Sepännen, M. R. J., Barmettler, S., Walter, J., Masmas, T. N., Mukhina, A. A., Falcone, E. L., Kracker, S., Shcherbina, A., Holland, S. M., Leto, T. L. & Hsu, A. P., Apr 11 2024, In: Blood. 143, 15, p. 1476-1487 12 p.

Research output: Contribution to journal › Article › peer-review

Cost-Effectiveness of Lovotibeglogene Autotemcel (Lovo-Cel) Gene Therapy for Patients with Sickle Cell Disease and Recurrent Vaso-Occlusive Events in the United States

Herring, W. L., Gallagher, M. E., Shah, N., Morse, K. C., Mladsi, D., Dong, O. M., Chawla, A., Leiding, J. W., Zhang, L., Paramore, C. & Andemariam, B., Jun 2024, In: PharmacoEconomics. 42, 6, p. 693-714 22 p.

Research output: Contribution to journal › Article › peer-review

Open Access

COVID-19 Vaccination in Patients with Inborn Errors of Immunity Reduces Hospitalization and Critical Care Needs Related to COVID-19: a USIDNET Report

McDonnell, J., Cousins, K., Younger, M. E. M., Lane, A., Abolhassani, H., Abraham, R. S., Al-Tamemi, S., Aldave-Becerra, J. C., Al-Faris, E. H., Alfaro-Murillo, A., AlKhater, S. A., Alsaati, N., Doss, A. M. A., Anderson, M., Angarola, E., Ariue, B., Arnold, D. E., Assa’ad, A. H., Aytekin, C. & Bank, M. & 138 others, Bergerson, J. R. E., Bleesing, J., Boesing, J., Bouso, C., Brodszki, N., Cabanillas, D., Cady, C., Callahan, M. A., Caorsi, R., Carbone, J., Carrabba, M., Castagnoli, R., Catanzaro, J. R., Chan, S., Chandra, S., Chapdelaine, H., Chavoshzadeh, Z., Chong, H. J., Connors, L., Consonni, F., Correa-Jimenez, O., Cunningham-Rundles, C., D’Astous-Gauthier, K., Delmonte, O. M., Demirdag, Y. Y., Deshpande, D. R., Diaz-Cabrera, N. M., Dimitriades, V. R., El-Owaidy, R., ElGhazali, G., Al-Hammadi, S., Fabio, G., Faure, A. S., Feng, J., Fernandez, J. M., Fill, L., Franco, G. R., Frenck, R. W., Fuleihan, R. L., Giardino, G., Galant-Swafford, J., Gambineri, E., Garabedian, E. K., Geerlinks, A. V., Goudouris, E., Grecco, O., Pan-Hammarström, Q., Khani, H. H. K., Hammarström, L., Hartog, N. L., Heimall, J., Hernandez-Molina, G., Horner, C. C., Hostoffer, R. W., Hristova, N., Hsiao, K. C., Ivankovich-Escoto, G., Jaber, F., Jalil, M., Jamee, M., Jean, T., Jeong, S., Jhaveri, D., Jordan, M. B., Joshi, A. Y., Kalkat, A., Kanarek, H. J., Kellner, E. S., Khojah, A., Khoury, R., Kokron, C. M., Kumar, A., Lecerf, K., Lehman, H. K., Leiding, J. W., Lesmana, H., Lim, X. R., Lopes, J. P., López, A. L., Tarquini, L., Lundgren, I. S., Magnusson, J., Marinho, A. K. B. B., Marseglia, G. L., Martone, G. M., Mechtler, A. G., Mendonca, L., Milner, J. D., Mustillo, P. J., Naderi, A. G., Naviglio, S., Nell, J., Niebur, H. B., Notarangelo, L., Oleastro, M., Ortega-López, M. C., Patel, N. R., Petrovic, G., Pignata, C., Porras, O., Prince, B. T., Puck, J. M., Qamar, N., Rabusin, M., Raje, N., Regairaz, L., Risma, K. A., Ristagno, E. H., Routes, J., Roxo-Junior, P., Salemi, N., Scalchunes, C., Schuval, S. J., Seneviratne, S. L., Shankar, A., Sherkat, R., Shin, J. J., Siddiqi, A., Signa, S., Sobh, A., Lima, F. M. S., Stenehjem, K. K., Tam, J. S., Tang, M., Barros, M. T., Verbsky, J., Vergadi, E., Voelker, D. H., Volpi, S., Wall, L. A., Wang, C., Williams, K. W., Wu, E. Y., Wu, S. S., Zhou, J. J., Cook, A., Sullivan, K. E. & Marsh, R., May 2024, In: Journal of Clinical Immunology. 44, 4, 86.

Research output: Contribution to journal › Article › peer-review

Open Access

High symptom burden in female X-linked chronic granulomatous disease carriers

Miranda, M. A., Tsalatsanis, A., Trotter, J. R., Arnold, D. E., Squire, J. D., Kidd, S., Parikh, S., Marsh, R. A., Griffith, L. M., Mallhi, K., Chellapandian, D., Lim, S. S., Grunebaum, E., Sullivan, K. E., Newburger, P. E., Dinauer, M. C., Cowan, M. J., Dvorak, C. C., Haddad, E. & Kohn, D. B. & 9 others, Notarangelo, L. D., Pai, S. Y., Puck, J. M., Pulsipher, M. A., Torgerson, T. R., Malech, H. L., Kang, E. M., Morton, F. B. & Leiding, J. W., Nov 2024, In: Clinical Immunology. 268, 110364.

Research output: Contribution to journal › Article › peer-review

Management of Atopy with Dupilumab and Omalizumab in CADINS Disease

Diaz-Cabrera, N. M., Bauman, B. M., Iro, M. A., Dabbah-Krancher, G., Molho-Pessach, V., Zlotogorski, A., Shamriz, O., Dinur-Schejter, Y., Sharon, T. D., Stepensky, P., Tal, Y., Eisenstein, E. M., Pietzsch, L., Schuetz, C., Abreu, D., Coughlin, C. C., Cooper, M. A., Milner, J. D., Williams, A. & Armoni-Weiss, G. & 2 others, Snow, A. L. & Leiding, J. W., Feb 2024, In: Journal of Clinical Immunology. 44, 2, 48.

Research output: Contribution to journal › Article › peer-review

Open Access

NADPH Oxidase 2-Derived Reactive Oxygen Species Promote CD8+ T Cell Effector Function

Chen, J., Liu, C., Chernatynskaya, A. V., Newby, B., Brusko, T. M., Xu, Y., Barra, J. M., Morgan, N., Santarlas, C., Reeves, W. H., Tse, H. M., Leiding, J. W. & Mathews, C. E., Jan 15 2024, In: Journal of Immunology. 212, 2, p. 258-270 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Posttransplantation late complications increase over time for patients with SCID: A Primary Immune Deficiency Treatment Consortium (PIDTC) landmark study

Eissa, H., Thakar, M. S., Shah, A. J., Logan, B. R., Griffith, L. M., Dong, H., Parrott, R. E., O'Reilly, R. J., Dara, J., Kapoor, N., Forbes Satter, L., Chandra, S., Kapadia, M., Chandrakasan, S., Knutsen, A., Jyonouchi, S. C., Molinari, L., Rayes, A., Ebens, C. L. & Teira, P. & 38 others, Dávila Saldaña, B. J., Burroughs, L. M., Chaudhury, S., Chellapandian, D., Gillio, A. P., Goldman, F., Malech, H. L., DeSantes, K., Cuvelier, G. D. E., Rozmus, J., Quinones, R., Yu, L. C., Broglie, L., Aquino, V., Shereck, E., Moore, T. B., Vander Lugt, M. T., Mousallem, T. I., Oved, J. H., Dorsey, M., Abdel-Azim, H., Martinez, C., Bleesing, J. H., Prockop, S., Kohn, D. B., Bednarski, J. J., Leiding, J., Marsh, R. A., Torgerson, T., Notarangelo, L. D., Pai, S. Y., Pulsipher, M. A., Puck, J. M., Dvorak, C. C., Haddad, E., Buckley, R. H., Cowan, M. J. & Heimall, J., Jan 2024, In: Journal of Allergy and Clinical Immunology. 153, 1, p. 287-296 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Real-world treatment patterns and outcomes in patients with primary hemophagocytic lymphohistiocytosis treated with emapalumab

the REAL-HLH Investigators, May 14 2024, In: Blood Advances. 8, 9, p. 2248-2258 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Relevance of lymphocyte proliferation to PHA in severe combined immunodeficiency (SCID) and T cell lymphopenia

Abraham, R. S., Basu, A., Heimall, J. R., Dunn, E., Yip, A., Kapadia, M., Kapoor, N., Satter, L. F., Buckley, R., O'Reilly, R., Cuvelier, G. D. E., Chandra, S., Bednarski, J., Chaudhury, S., Moore, T. B., Haines, H., Dávila Saldaña, B. J., Chellapandian, D., Rayes, A. & Chen, K. & 37 others, Caywood, E., Chandrakasan, S., Lugt, M. T. V., Ebens, C., Teira, P., Shereck, E., Miller, H., Aquino, V., Eissa, H., Yu, L. C., Gillio, A., Madden, L., Knutsen, A., Shah, A. J., DeSantes, K., Barnum, J., Broglie, L., Joshi, A. Y., Kleiner, G., Dara, J., Prockop, S., Martinez, C., Mousallem, T., Oved, J., Burroughs, L., Marsh, R., Torgerson, T. R., Leiding, J. W., Pai, S. Y., Kohn, D. B., Pulsipher, M. A., Griffith, L. M., Notarangelo, L. D., Cowan, M. J., Puck, J., Dvorak, C. C. & Haddad, E., Apr 2024, In: Clinical Immunology. 261, 109942.

Research output: Contribution to journal › Article › peer-review

Severe clinical phenotypes of heterozygous females with X-linked chronic granulomatous disease

Patel, N. C., Younger, M. E. M., Williams, K., Matias Lopes, J. P., Kuhns, D. B., Patel, M. N., Miranda, M. A., Marciano, B. E., Deal, C. L. & Leiding, J. W., Dec 2024, In: Journal of Allergy and Clinical Immunology: In Practice. 12, 12, p. 3452-3456.e1

Research output: Contribution to journal › Article › peer-review

Open Access

2023

Activated phosphoinositide 3-kinase δ syndrome: Update from the ESID Registry and comparison with other autoimmune-lymphoproliferative inborn errors of immunity

European Society for Immunodeficiencies Registry Working Party, Oct 2023, In: Journal of Allergy and Clinical Immunology. 152, 4, p. 984-996.e10

Research output: Contribution to journal › Article › peer-review

Open Access

Disseminated mycobacterial infections after tumor necrosis factor inhibitor use, revealing inborn errors of immunity

Squire, J. D., Libertin, C. R., Powers, H., Nelson, J., Brumble, L., Laham, F. R., Agharahimi, A., Freeman, A. F. & Leiding, J. W., Jun 2023, In: International Journal of Infectious Diseases. 131, p. 162-165 4 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Genotype, oxidase status, and preceding infection or autoinflammation do not affect allogeneic HCT outcomes for CGD

Leiding, J. W., Arnold, D. E., Parikh, S., Logan, B., Marsh, R. A., Griffith, L. M., Wu, R., Kidd, S., Mallhi, K., Chellapandian, D., Si Lim, S. J., Grunebaum, E., Falcone, E. L., Murguia-Favela, L., Grossman, D., Prasad, V. K., Heimall, J. R., Touzot, F., Burroughs, L. M. & Bleesing, J. & 49 others, Kapoor, N., Dara, J., Williams, O., Kapadia, M., Oshrine, B. R., Bednarski, J. J., Rayes, A., Chong, H., Cuvelier, G. D. E., Forbes Satter, L. R., Martinez, C., Vander Lugt, M. T., Yu, L. C., Chandrakasan, S., Joshi, A., Prockop, S. E., Dávila Saldaña, B. J., Aquino, V., Broglie, L. A., Ebens, C. L., Madden, L. M., DeSantes, K., Milner, J., Rangarajan, H. G., Shah, A. J., Gillio, A. P., Knutsen, A. P., Miller, H. K., Moore, T. B., Graham, P., Bauchat, A., Bunin, N. J., Teira, P., Petrovic, A., Chandra, S., Abdel-Azim, H., Dorsey, M. J., Birbrayer, O., Cowan, M. J., Dvorak, C. C., Haddad, E., Kohn, D. B., Notarangelo, L. D., Pai, S. Y., Puck, J. M., Pulsipher, M. A., Torgerson, T. R., Malech, H. L. & Kang, E. M., Dec 14 2023, In: Blood. 142, 24, p. 2105-2118 14 p.

Research output: Contribution to journal › Article › peer-review

Hypomorphic RAG deficiency: impact of disease burden on survival and thymic recovery argues for early diagnosis and HSCT

Inborn Errors Working Party (IEWP) of the European Society for Immunodeficiencies (ESID) and European Society for Blood and Marrow Transplantation (EBMT) and the Primary Immune Deficiency Treatment Consortium (PIDTC), Feb 16 2023, In: Blood. 141, 7, p. 713-724 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Intestinal microbiome and metabolome signatures in patients with chronic granulomatous disease

Chandrasekaran, P., Han, Y., Zerbe, C. S., Heller, T., DeRavin, S. S., Kreuzberg, S. A., Marciano, B. E., Siu, Y., Jones, D. R., Abraham, R. S., Stephens, M. C., Tsou, A. M., Snapper, S., Conlan, S., Subramanian, P., Quinones, M., Grou, C., Calderon, V., Deming, C. & Leiding, J. W. & 37 others, Arnold, D. E., Logan, B. R., Griffith, L. M., Petrovic, A., Mousallem, T. I., Kapoor, N., Heimall, J. R., Barnum, J. L., Kapadia, M., Wright, N., Rayes, A., Chandra, S., Broglie, L. A., Chellapandian, D., Deal, C. L., Grunebaum, E., Lim, S. S., Mallhi, K., Marsh, R. A., Murguia-Favela, L., Parikh, S., Touzot, F., Cowan, M. J., Dvorak, C. C., Haddad, E., Kohn, D. B., Notarangelo, L. D., Pai, S. Y., Puck, J. M., Pulsipher, M. A., Torgerson, T. R., Kang, E. M., Malech, H. L., Segre, J. A., Bryant, C. E., Holland, S. M. & Falcone, E. L., Dec 2023, In: Journal of Allergy and Clinical Immunology. 152, 6, p. 1619-1633.e11

Research output: Contribution to journal › Article › peer-review

Open Access

Measuring the effect of newborn screening on survival after haematopoietic cell transplantation for severe combined immunodeficiency: a 36-year longitudinal study from the Primary Immune Deficiency Treatment Consortium

Thakar, M. S., Logan, B. R., Puck, J. M., Dunn, E. A., Buckley, R. H., Cowan, M. J., O'Reilly, R. J., Kapoor, N., Satter, L. F., Pai, S. Y., Heimall, J., Chandra, S., Ebens, C. L., Chellapandian, D., Williams, O., Burroughs, L. M., Saldana, B. D., Rayes, A., Madden, L. M. & Chandrakasan, S. & 45 others, Bednarski, J. J., DeSantes, K. B., Cuvelier, G. D. E., Teira, P., Gillio, A. P., Eissa, H., Knutsen, A. P., Goldman, F. D., Aquino, V. M., Shereck, E. B., Moore, T. B., Caywood, E. H., Lugt, M. T. V., Rozmus, J., Broglie, L., Yu, L. C., Shah, A. J., Andolina, J. R., Liu, X., Parrott, R. E., Dara, J., Prockop, S., Martinez, C. A., Kapadia, M., Jyonouchi, S. C., Sullivan, K. E., Bleesing, J. J., Chaudhury, S., Petrovic, A., Keller, M. D., Quigg, T. C., Parikh, S., Shenoy, S., Seroogy, C., Rubin, T., Decaluwe, H., Routes, J. M., Torgerson, T. R., Leiding, J. W., Pulsipher, M. A., Kohn, D. B., Griffith, L. M., Haddad, E., Dvorak, C. C. & Notarangelo, L. D., Jul 8 2023, In: The Lancet. 402, 10396, p. 129-140 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Monogenic early-onset lymphoproliferation and autoimmunity: Natural history of STAT3 gain-of-function syndrome

STAT3 GOF Working Group members, Apr 2023, In: Journal of Allergy and Clinical Immunology. 151, 4, p. 1081-1095 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

NOX2 deficiency enhances priming and activation of the NLRP3 inflammasome

Monjarret, B., Shour, S., Benyoucef, A., Heckel, E., Marchitto, L., Leiding, J. W., Cros, G., Fernandez, I., Joyal, J. S. & Touzot, F., 2023, (Accepted/In press) In: Journal of Allergy and Clinical Immunology.

Research output: Contribution to journal › Article › peer-review

Reappraisal of Idiopathic CD4 Lymphocytopenia at 30 Years

Lisco, A., Ortega-Villa, A. M., Mystakelis, H., Anderson, M. V., Mateja, A., Laidlaw, E., Manion, M., Roby, G., Higgins, J., Kuriakose, S., Walkiewicz, M. A., Similuk, M., Leiding, J. W., Freeman, A. F., Sheikh, V. & Sereti, I., 2023, In: New England Journal of Medicine. 388, 18, p. 1680-1691 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

The diagnosis of severe combined immunodeficiency: Implementation of the PIDTC 2022 Definitions

Dvorak, C. C., Haddad, E., Heimall, J., Dunn, E., Cowan, M. J., Pai, S. Y., Kapoor, N., Satter, L. F., Buckley, R. H., O'Reilly, R. J., Chandra, S., Bednarski, J. J., Williams, O., Rayes, A., Moore, T. B., Ebens, C. L., Davila Saldana, B. J., Petrovic, A., Chellapandian, D. & Cuvelier, G. D. E. & 31 others, Vander Lugt, M. T., Caywood, E. H., Chandrakasan, S., Eissa, H., Goldman, F. D., Shereck, E., Aquino, V. M., Desantes, K. B., Madden, L. M., Miller, H. K., Yu, L., Broglie, L., Gillio, A., Shah, A. J., Knutsen, A. P., Andolina, J. P., Joshi, A. Y., Szabolcs, P., Kapadia, M., Martinez, C. A., Parrot, R. E., Sullivan, K. E., Prockop, S. E., Abraham, R. S., Thakar, M. S., Leiding, J. W., Kohn, D. B., Pulsipher, M. A., Griffith, L. M., Notarangelo, L. D. & Puck, J. M., Feb 2023, In: Journal of Allergy and Clinical Immunology. 151, 2, p. 547-555.e5

Research output: Contribution to journal › Article › peer-review

Open Access

2022

A human STAT3 gain-of-function variant confers T cell dysregulation without predominant Treg dysfunction in mice

Schmitt, E. G., Toth, K. A., Risma, S. I., Kolicheski, A., Saucier, N., Feliciano Berríos, R. J., Greenberg, Z. J., Leiding, J. W., Bleesing, J. J., Thatayatikom, A., Schuettpelz, L. G., Edwards, J. R., Vogel, T. P. & Cooper, M. A., Nov 8 2022, In: JCI Insight. 7, 21, e162695.

Research output: Contribution to journal › Article › peer-review

Open Access

Case Report: Unmanipulated Matched Sibling Donor Hematopoietic Cell Transplantation In TBX1 Congenital Athymia: A Lifesaving Therapeutic Approach When Facing a Systemic Viral Infection

Chitty-Lopez, M., Duff, C., Vaughn, G., Trotter, J., Monforte, H., Lindsay, D., Haddad, E., Keller, M. D., Oshrine, B. & Leiding, J. W., Jan 14 2022, In: Frontiers in immunology. 12, 721917.

Research output: Contribution to journal › Article › peer-review

Open Access

Granulocyte Transfusions in Patients with Chronic Granulomatous Disease Undergoing Hematopoietic Cell Transplantation or Gene Therapy

Arnold, D. E., Chellapandian, D., Parikh, S., Mallhi, K., Marsh, R. A., Heimall, J. R., Grossman, D., Chitty-Lopez, M., Murguia-Favela, L., Gennery, A. R., Boulad, F., Arbuckle, E., Cowan, M. J., Dvorak, C. C., Griffith, L. M., Haddad, E., Kohn, D. B., Notarangelo, L. D., Pai, S. Y. & Puck, J. M. & 5 others, Pulsipher, M. A., Torgerson, T., Kang, E. M., Malech, H. L. & Leiding, J. W., Jul 2022, In: Journal of Clinical Immunology. 42, 5, p. 1026-1035 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Outcomes following treatment for ADA-deficient severe combined immunodeficiency: a report from the PIDTC

Cuvelier, G. D. E., Logan, B. R., Prockop, S. E., Buckley, R. H., Kuo, C. Y., Griffith, L. M., Liu, X., Yip, A., Hershfield, M. S., Ayoub, P. G., Moore, T. B., Dorsey, M. J., O'Reilly, R. J., Kapoor, N., Pai, S. Y., Kapadia, M., Ebens, C. L., Forbes Satter, L. R., Burroughs, L. M. & Petrovic, A. & 30 others, Chellapandian, D., Heimall, J., Shyr, D. C., Rayes, A., Bednarski, J. J., Chandra, S., Chandrakasan, S., Gillio, A. P., Madden, L., Quigg, T. C., Caywood, E. H., Dávila Saldaña, B. J., DeSantes, K., Eissa, H., Goldman, F. D., Rozmus, J., Shah, A. J., Vander Lugt, M. T., Thakar, M. S., Parrott, R. E., Martinez, C., Leiding, J. W., Torgerson, T. R., Pulsipher, M. A., Notarangelo, L. D., Cowan, M. J., Dvorak, C. C., Haddad, E., Puck, J. M. & Kohn, D. B., Aug 18 2022, In: Blood. 140, 7, p. 685-705 21 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Partial RAG deficiency in humans induces dysregulated peripheral lymphocyte development and humoral tolerance defect with accumulation of T-bet⁺ B cells

Csomos, K., Ujhazi, B., Blazso, P., Herrera, J. L., Tipton, C. M., Kawai, T., Gordon, S., Ellison, M., Wu, K., Stowell, M., Haynes, L., Cruz, R., Zakota, B., Nguyen, J., Altrich, M., Geier, C. B., Sharapova, S., Dasso, J. F., Leiding, J. W. & Smith, G. & 30 others, Al-Herz, W., de Barros Dorna, M., Fadugba, O., Fronkova, E., Kanderova, V., Svaton, M., Henrickson, S. E., Hernandez, J. D., Kuijpers, T., Kandilarova, S. M., Naumova, E., Milota, T., Sediva, A., Moshous, D., Neven, B., Saco, T., Sargur, R., Savic, S., Sleasman, J., Sunkersett, G., Ward, B. R., Komatsu, M., Pittaluga, S., Kumanovics, A., Butte, M. J., Cancro, M. P., Pillai, S., Meffre, E., Notarangelo, L. D. & Walter, J. E., Aug 2022, In: Nature Immunology. 23, 8, p. 1256-1272 17 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Precision Medicine in the Treatment of Primary Immune Deficiency Patients With Disorders of Immune Dysregulation

Ballow, M. & Leiding, J. W., Aug 2022, In: Clinical Reviews in Allergy and Immunology. 63, 1, p. 1-8 8 p.

Research output: Contribution to journal › Article › peer-review

STAT3 gain-of-function mutations connect leukemia with autoimmune disease by pathological NKG2D^hi CD8⁺ T cell dysregulation and accumulation

Masle-Farquhar, E., Jackson, K. J. L., Peters, T. J., Al-Eryani, G., Singh, M., Payne, K. J., Rao, G., Avery, D. T., Apps, G., Kingham, J., Jara, C. J., Skvortsova, K., Swarbrick, A., Ma, C. S., Suan, D., Uzel, G., Chua, I., Leiding, J. W., Heiskanen, K. & Preece, K. & 11 others, Kainulainen, L., O'Sullivan, M., Cooper, M. A., Seppänen, M. R. J., Mustjoki, S., Brothers, S., Vogel, T. P., Brink, R., Tangye, S. G., Reed, J. H. & Goodnow, C. C., Dec 13 2022, In: Immunity. 55, 12, p. 2386-2404.e8

Research output: Contribution to journal › Article › peer-review

Open Access

2021

Infections in Infants with SCID: Isolation, Infection Screening, and Prophylaxis in PIDTC Centers

Dorsey, M. J., Wright, N. A. M., Chaimowitz, N. S., Dávila Saldaña, B. J., Miller, H., Keller, M. D., Thakar, M. S., Shah, A. J., Abu-Arja, R., Andolina, J., Aquino, V., Barnum, J. L., Bednarski, J. J., Bhatia, M., Bonilla, F. A., Butte, M. J., Bunin, N. J., Chandra, S., Chaudhury, S. & Chen, K. & 39 others, Chong, H., Cuvelier, G. D. E., Dalal, J., DeFelice, M. L., DeSantes, K. B., Forbes, L. R., Gillio, A., Goldman, F., Joshi, A. Y., Kapoor, N., Knutsen, A. P., Kobrynski, L., Lieberman, J. A., Leiding, J. W., Oshrine, B., Patel, K. P., Prockop, S., Quigg, T. C., Quinones, R., Schultz, K. R., Seroogy, C., Shyr, D., Siegel, S., Smith, A. R., Torgerson, T. R., Vander Lugt, M. T., Yu, L. C., Cowan, M. J., Buckley, R. H., Dvorak, C. C., Griffith, L. M., Haddad, E., Kohn, D. B., Logan, B., Notarangelo, L. D., Pai, S. Y., Puck, J., Pulsipher, M. A. & Heimall, J., Jan 2021, In: Journal of Clinical Immunology. 41, 1, p. 38-50 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Primary Immunodeficiency in Children With Autoimmune Cytopenias: Retrospective 154-Patient Cohort

Westermann-Clark, E., Meehan, C. A., Meyer, A. K., Dasso, J. F., Amre, D., Ellison, M., Patel, B., Betensky, M., Hauk, C. I., Mayer, J., Metts, J., Leiding, J. W., Sriaroon, P., Kumar, A., Ayala, I. & Walter, J. E., Apr 22 2021, In: Frontiers in immunology. 12, 649182.

Research output: Contribution to journal › Article › peer-review

Open Access

STAT3 Gain-of-Function Mutations Underlie Deficiency in Human Nonclassical CD16⁺ Monocytes and CD141⁺ Dendritic Cells

Korenfeld, D., Roussak, K., Dinkel, S., Vogel, T. P., Pollack, H., Levy, J., Leiding, J. W., Milner, J., Cooper, M. & Klechevsky, E., Nov 15 2021, In: Journal of Immunology. 207, 10, p. 2423-2432 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2020

Asymptomatic Infant With Atypical SCID and Novel Hypomorphic RAG Variant Identified by Newborn Screening: A Diagnostic and Treatment Dilemma

Chitty-Lopez, M., Westermann-Clark, E., Dawson, I., Ujhazi, B., Csomos, K., Dobbs, K., Le, K., Yamazaki, Y., Sadighi Akha, A. A., Chellapandian, D., Oshrine, B., Notarangelo, L. D., Sunkersett, G., Leiding, J. W. & Walter, J. E., Sep 29 2020, In: Frontiers in immunology. 11, 1954.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Brain Abscess as Severe Presentation of Specific Granule Deficiency

Leszcynska, M., Patel, B., Morrow, M., Chamizo, W., Tuite, G., Berman, D., Potthast, K., Hsu, A. P., Holland, S. M. & Leiding, J. W., Apr 22 2020, In: Frontiers in Pediatrics. 8, 117.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Case Report: Secondary Hemophagocytic Lymphohistiocytosis With Disseminated Infection in Chronic Granulomatous Disease—A Serious Cause of Mortality

Squire, J. D., Vazquez, S. N., Chan, A., Smith, M. E., Chellapandian, D., Vose, L., Teppa, B., Hanson, I. C., Chinn, I. K., Forbes-Satter, L., Seeborg, F. O., Nicholas, S. K., Martinez, C. A., Allen, C. E., Connors, T. J., Satwani, P., Shtessel, M., Ale, H., Noroski, L. M. & Rider, N. L. & 2 others, Milner, J. D. & Leiding, J. W., Dec 9 2020, In: Frontiers in immunology. 11, 581475.

Research output: Contribution to journal › Article › peer-review

Open Access

Diagnostic assay to assist clinical decisions for unclassified severe combined immune deficiency

Bifsha, P., Leiding, J. W., Pai, S. Y., Colamartino, A. B. L., Hartog, N., Church, J. A., Oshrine, B., Puck, J. M., Markert, M. L. & Haddad, E., Jun 23 2020, In: Blood Advances. 4, 12, p. 2606-2610 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

Diagnostic interpretation of genetic studies in patients with primary immunodeficiency diseases: A working group report of the Primary Immunodeficiency Diseases Committee of the American Academy of Allergy, Asthma & Immunology

Chinn, I. K., Chan, A. Y., Chen, K., Chou, J., Dorsey, M. J., Hajjar, J., Jongco, A. M., Keller, M. D., Kobrynski, L. J., Kumanovics, A., Lawrence, M. G., Leiding, J. W., Lugar, P. L., Orange, J. S., Patel, K., Platt, C. D., Puck, J. M., Raje, N., Romberg, N. & Slack, M. A. & 4 others, Sullivan, K. E., Tarrant, T. K., Torgerson, T. R. & Walter, J. E., Jan 2020, In: Journal of Allergy and Clinical Immunology. 145, 1, p. 46-69 24 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Hematopoietic Cell Transplantation in Patients With Primary Immune Regulatory Disorders (PIRD): A Primary Immune Deficiency Treatment Consortium (PIDTC) Survey

Chan, A. Y., Leiding, J., Liu, X., Logan, B. R., Burroughs, L. M., Allenspach, E. J., Skoda-Smith, S., Uzel, G., Notarangelo, L. D., Slatter, M., Gennery, A. R., Smith, A. R., Pai, S. Y., Jordan, M. B., Marsh, R. A., Cowan, M. J., Dvorak, C. C., Craddock, J. A., Prockop, S. E. & Chandrakasan, S. & 40 others, Kapoor, N., Buckley, R. H., Parikh, S., Chellapandian, D., Oshrine, B. R., Bednarski, J. J., Cooper, M. A., Shenoy, S., Davila Saldana, B. J., Forbes, L. R., Martinez, C., Haddad, E., Shyr, D. C., Chen, K., Sullivan, K. E., Heimall, J., Wright, N., Bhatia, M., Cuvelier, G. D. E., Goldman, F. D., Meyts, I., Miller, H. K., Seidel, M. G., Vander Lugt, M. T., Bacchetta, R., Weinacht, K. G., Andolina, J. R., Caywood, E., Chong, H., de la Morena, M. T., Aquino, V. M., Shereck, E., Walter, J. E., Dorsey, M. J., Seroogy, C. M., Griffith, L. M., Kohn, D. B., Puck, J. M., Pulsipher, M. A. & Torgerson, T. R., Feb 21 2020, In: Frontiers in immunology. 11, 239.

Research output: Contribution to journal › Article › peer-review

Open Access

6 Scopus citations

High-flow 20% subcutaneous immunoglobulin G in patients with primary immunodeficiency disease

McCrary, K., Leiding, J. W. & Duff, C., Sep 2020, In: Annals of Allergy, Asthma and Immunology. 125, 3, p. 344-346 3 p.

Research output: Contribution to journal › Article › peer-review

2019

Chronic Granulomatous Disease-Associated IBD Resolves and Does Not Adversely Impact Survival Following Allogeneic HCT

submitted on behalf of the Primary Immune Deficiency Treatment Consortium, Oct 1 2019, In: Journal of Clinical Immunology. 39, 7, p. 653-667 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

Mechanism-Based Precision Therapy for the Treatment of Primary Immunodeficiency and Primary Immunodysregulatory Diseases

Leiding, J. W. & Forbes, L. R., Mar 2019, In: Journal of Allergy and Clinical Immunology: In Practice. 7, 3, p. 761-773 13 p.

Research output: Contribution to journal › Article › peer-review

Mycobacteria-specific T cells may be expanded from healthy donors and are near absent in primary immunodeficiency disorders

Patel, S., Lang, H., Sani, G., Freeman, A. F., Leiding, J., Hanley, P. J., Cruz, C. R., Grant, M., Wang, Y., Oshrine, B., Palmer, C., Holland, S. M., Bollard, C. M. & Keller, M. D., 2019, In: Frontiers in immunology. 10, MAR, 621.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

Neutrophil cytosolic factor 1 in dendritic cells promotes autoreactive CD8⁺ T cell activation via cross-presentation in type 1 diabetes

Liu, C., Whitener, R. L., Lin, A., Xu, Y., Chen, J., Savinov, A., Leiding, J. W., Wallet, M. A. & Mathews, C. E., 2019, In: Frontiers in immunology. 10, MAY, 952.

Research output: Contribution to journal › Article › peer-review

Open Access

Two Unique Cases of X-linked SCID: A Diagnostic Challenge in the Era of Newborn Screening

Purswani, P., Meehan, C. A., Kuehn, H. S., Chang, Y., Dasso, J. F., Meyer, A. K., Ujhazi, B., Csomos, K., Lindsay, D., Alberdi, T., Joychan, S., Trotter, J., Duff, C., Ellison, M., Bleesing, J., Kumanovics, A., Comeau, A. M., Hale, J. E., Notarangelo, L. D. & Torgersen, T. R. & 7 others, Ochs, H. D., Sriaroon, P., Oshrine, B., Petrovic, A., Rosenzweig, S. D., Leiding, J. W. & Walter, J. E., Apr 5 2019, In: Frontiers in Pediatrics. 7, 55.

Research output: Contribution to journal › Article › peer-review

Open Access

2018

Hematopoietic stem cell transplantation in patients with gain-of-function signal transducer and activator of transcription 1 mutations

Inborn Errors Working Party of the European Society for Blood and Marrow Transplantation and the Primary Immune Deficiency Treatment Consortium, Feb 2018, In: Journal of Allergy and Clinical Immunology. 141, 2, p. 704-717.e5

Research output: Contribution to journal › Article › peer-review

Open Access

Jennifer Leiding

Research output

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