Ilan Wittstein

Research output

Research output per year 1993 2007 2012 2016 2022 2023

• 46 Article
• 6 Review article
• 4 Chapter
• 4 Editorial
• 5 More
  • 3 Letter
  • 2 Comment/debate

Research output per year

Research output per year

Search results

• 2023

  High Coronary Artery Calcium Score Is Associated With Increased Major Adverse Cardiac Events After Liver Transplantation

  Su, A., Almazan, E., Sakulsaengprapha, V., Shay, J., Wittstein, I., Hammami, M., Pustavoitau, A., Rizkalla, N., Alqahtani, S., Woreta, T., Hamilton, J. P., Kohli, R., Ottmann, S. E., Gurakar, A. & Chen, P. H., Jan 6 2023, In: Transplantation Direct. 9, 2, p. E1426

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Liver Transplantation 100%
  • Coronary Vessels 89%
  • Calcium 75%
  • Mortality 13%
  • Vulnerable Populations 9%

• Serum Proteomic Analysis of Peripartum Cardiomyopathy Reveals Distinctive Dysregulation of Inflammatory and Cholesterol Metabolism Pathways

  IPAC & IMAC2 Investigators, Sep 2023, In: JACC: Heart Failure. 11, 9, p. 1231-1242 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Peripartum Period 100%
  • Cardiomyopathies 73%
  • Proteomics 69%
  • Cholesterol 55%
  • Serum 34%
• 2022

  Heart transplantation outcomes in arrhythmogenic right ventricular cardiomyopathy: a contemporary national analysis

  Giuliano, K., Scheel, P., Etchill, E., Fraser, C. D., Suarez-Pierre, A., Hsu, S., Wittstein, I. S., Kasper, E. K., Florido, R., Tandri, H., Calkins, H., Choi, C. W., Sharma, K., Kilic, A. & Gilotra, N. A., Apr 2022, In: ESC Heart Failure. 9, 2, p. 988-997 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Arrhythmogenic Right Ventricular Dysplasia 100%
  • Heart Transplantation 75%
  • Cardiomyopathies 27%
  • Arrhythmogenic Right Ventricular Dysplasia, Familial, 8 10%
  • Survival 7%

• Neurocardiac Changes Preceding and During the Onset of Takotsubo Cardiomyopathy in the Cardiac Electrophysiology Laboratory

  Thirumal, R., Wittstein, I. S., Calkins, H. & DeMazumder, D., Feb 2022, In: JACC: Clinical Electrophysiology. 8, 2, p. 275-276 2 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Stress-Induced (Takotsubo) Cardiomyopathy After Liver Transplant Rescued with Venoarterial Extracorporeal Membrane Oxygenation

  Caturegli, G., Crane, M. A., Etchill, E., Giuliano, K., Nguyen, M., Philosophe, B., Cho, S. M., Wittstein, I. S. & Whitman, G. J. R., Apr 1 2022, In: ASAIO Journal. 68, 4, p. E66-E68

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Oxygenation 100%
  • Transplants 99%
  • Takotsubo Cardiomyopathy 95%
  • Liver 83%
  • Extracorporeal Membrane Oxygenation 82%
• 2021

  Endothelial Stromal PD-L1 (Programmed Death Ligand 1) Modulates CD8⁺T-Cell Infiltration after Heart Transplantation

  Bracamonte-Baran, W., Gilotra, N. A., Won, T., Rodriguez, K. M., Talor, M. V., Oh, B. C., Griffin, J., Wittstein, I., Sharma, K., Skinner, J., Johns, R. A., Russell, S. D., Anders, R. A., Zhu, Q., Halushka, M. K., Brandacher, G. & Čiháková, D., Oct 1 2021, In: Circulation: Heart Failure. 14, 10, p. e007982

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Heart Transplantation 100%
  • Ligands 66%
  • T-Lymphocytes 58%
  • Transplants 35%
  • Leukocytes 22%
• 2019

  Breastfeeding, Cellular Immune Activation, and Myocardial Recovery in Peripartum Cardiomyopathy

  IPAC Investigators, Jun 2019, In: JACC: Basic to Translational Science. 4, 3, p. 291-300 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Peripartum Period 100%
  • Breast Feeding 75%
  • Prolactin 74%
  • Cardiomyopathies 73%
  • Bromocriptine 15%
  9 Scopus citations
• 2018

  Circulating T-Cell Subsets, Monocytes, and Natural Killer Cells in Peripartum Cardiomyopathy: Results From the Multicenter IPAC Study

  for the IPAC Investigators, Jan 1 2018, In: Journal of cardiac failure. 24, 1, p. 33-42 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Peripartum Period 100%
  • T-Lymphocyte Subsets 80%
  • Cardiomyopathies 73%
  • Natural Killer Cells 70%
  • Monocytes 62%
  4 Scopus citations

• International Expert Consensus Document on Takotsubo Syndrome (Part I): Clinical Characteristics, Diagnostic Criteria, and Pathophysiology

  Ghadri, J. R., Wittstein, I. S., Prasad, A., Sharkey, S., Dote, K., Akashi, Y. J., Cammann, V. L., Crea, F., Galiuto, L., Desmet, W., Yoshida, T., Manfredini, R., Eitel, I., Kosuge, M., Nef, H. M., Deshmukh, A., Lerman, A., Bossone, E., Citro, R., Ueyama, T., & 16 othersCorrado, D., Kurisu, S., Ruschitzka, F., Winchester, D., Lyon, A. R., Omerovic, E., Bax, J. J., Meimoun, P., Tarantini, G., Rihal, C., Hassan, S. Y., Migliore, F., Horowitz, J. D., Shimokawa, H., Lüscher, T. F. & Templin, C., Jun 7 2018, In: European heart journal. 39, 22, p. 2032-2046 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Takotsubo Cardiomyopathy 100%
  • Terminology 10%
  • Coronary Artery Disease 8%
  • Heart Diseases 8%
  • Guidelines 6%
  356 Scopus citations

• International Expert Consensus Document on Takotsubo Syndrome (Part II): Diagnostic Workup, Outcome, and Management

  Ghadri, J. R., Wittstein, I. S., Prasad, A., Sharkey, S., Dote, K., Akashi, Y. J., Cammann, V. L., Crea, F., Galiuto, L., Desmet, W., Yoshida, T., Manfredini, R., Eitel, I., Kosuge, M., Nef, H. M., Deshmukh, A., Lerman, A., Bossone, E., Citro, R., Ueyama, T., & 16 othersCorrado, D., Kurisu, S., Ruschitzka, F., Winchester, D., Lyon, A. R., Omerovic, E., Bax, J. J., Meimoun, P., Tarantini, G., Rihal, C., Hassan, S. Y., Migliore, F., Horowitz, J. D., Shimokawa, H., Lüscher, T. F. & Templin, C., Jun 7 2018, In: European heart journal. 39, 22, p. 2047-2062 16 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Takotsubo Cardiomyopathy 100%
  • Risk Management 26%
  • Patient Care 18%
  • Clinical Trials 15%
  • Physicians 15%
  199 Scopus citations

• The Role of Emotional Competence in Takotsubo Cardiomyopathy

  Compare, A., Brugnera, A., Spada, M. M., Zarbo, C., Tasca, G. A., Sassaroli, S., Caselli, G., Ruggiero, G. M. & Wittstein, I., May 1 2018, In: Psychosomatic medicine. 80, 4, p. 377-384 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Takotsubo Cardiomyopathy 100%
  • mood 70%
  • Mental Competency 69%
  • emotional intelligence 53%
  • emotion 52%
  7 Scopus citations
• 2017

  Myocardial Recovery in Patients With Systolic Heart Failure and Autoantibodies Against β₁-Adrenergic Receptors

  Nagatomo, Y., McNamara, D. M., Alexis, J. D., Cooper, L. T., Dec, G. W., Pauly, D. F., Sheppard, R., Starling, R. C., Tang, W. H. W., Janosko, K., McTiernan, C., London, B., Hanley-Yanez, K., Gorcsan, J., Tanaka, H., Suffoletto, M., Oblak, C., McNallan, A., Koenig, L. A., Mather, P., & 28 othersPierson, N., Rubin, S., Bell, Y., Ervin, A., Boehmer, J., Frey, P., Alexis, J., Schrack, J., LaDuke, P., Torre-Amione, G., Arredondo, J., Smith, P. C., Fuoco, S., Wittstein, I. S., Breton, E., Thohan, V., Wesley, D., Cocca-Spofford, D., Markham, D. W., Fernandez, L., Debes, C., Zucker, M. J., Adams, L., Liu, P., Renton, J., Narula, J., Allen, B. & Westberg, E., Feb 28 2017, In: Journal of the American College of Cardiology. 69, 8, p. 968-977 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Systolic Heart Failure 100%
  • Adrenergic Receptors 70%
  • Autoantibodies 68%
  • Immunoglobulins 65%
  • Stroke Volume 47%
  13 Scopus citations

• Usefulness of Pulse Amplitude Changes During the Valsalva Maneuver Measured Using Finger Photoplethysmography to Identify Elevated Pulmonary Capillary Wedge Pressure in Patients With Heart Failure

  Gilotra, N. A., Tedford, R., Wittstein, I. S., Yenokyan, G., Sharma, K., Russell, S. & Silber, H. A., Sep 15 2017, In: American Journal of Cardiology. 120, 6, p. 966-972 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Photoplethysmography 100%
  • Valsalva Maneuver 89%
  • Pulmonary Wedge Pressure 83%
  • Pulse 77%
  • Fingers 62%
  5 Scopus citations
• 2016

  Baseline Characteristics Predict the Presence of Amyloid on Endomyocardial Biopsy

  Ton, V. K., Bhonsale, A., Gilotra, N. A., Halushka, M. K., Steenbergen, C., Almansa, J., Brown, E., Tedford, R., Wittstein, I., Sharma, K., Russell, S. & Judge, D. P., Mar 7 2016, (Accepted/In press) In: Journal of Cardiac Failure.

  Research output: Contribution to journal › Article › peer-review

  • Amyloidosis 100%
  • Amyloid 85%
  • Biopsy 54%
  • Heart Failure 26%
  • Peripheral Nervous System Diseases 18%
  5 Scopus citations

• Psychiatric history, post-discharge distress, and personality characteristics among incident female cases of takotsubo cardiomyopathy: A case–control study

  Salmoirago-Blotcher, E., Rosman, L., Wittstein, I. S., Dunsiger, S., Swales, H. H., Aurigemma, G. P. & Ockene, I. S., Nov 1 2016, In: Heart and Lung. 45, 6, p. 503-509 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Takotsubo Cardiomyopathy 100%
  • Personality 65%
  • Psychiatry 54%
  • Myocardial Infarction 28%
  • Post-Traumatic Stress Disorders 26%
  16 Scopus citations

• Reproductive History of Women With Takotsubo Cardiomyopathy

  Salmoirago-Blotcher, E., Dunsiger, S., Swales, H. H., Aurigemma, G. P., Ockene, I., Rosman, L. & Wittstein, I. S., Dec 15 2016, In: American Journal of Cardiology. 118, 12, p. 1922-1928 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Takotsubo Cardiomyopathy 100%
  • Reproductive History 90%
  • Myocardial Infarction 22%
  • Menstruation Disturbances 14%
  • Logistic Models 13%
  4 Scopus citations

• Shared genetic predisposition in Peripartum and dilated cardiomyopathies

  Ware, J. S., Li, J., Mazaika, E., Yasso, C. M., De Souza, T., Cappola, T. P., Tsai, E. J., Hilfiker-Kleiner, D., Kamiya, C. A., Mazzarotto, F., Cook, S. A., Halder, I., Prasad, S. K., Pisarcik, J., Hanley-Yanez, K., Alharethi, R., Damp, J., Hsich, E., Elkayam, U., Sheppard, R., & 15 othersKealey, A., Alexis, J., Ramani, G., Safirstein, J., Boehmer, J., Pauly, D. F., Wittstein, I. S., Thohan, V., Zucker, M. J., Liu, P., Gorcsan, J., McNamara, D. M., Seidman, C. E., Seidman, J. G. & Arany, Z., Jan 21 2016, In: New England Journal of Medicine. 374, 3, p. 233-241 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Peripartum Period 100%
  • Dilated Cardiomyopathy 82%
  • Genetic Predisposition to Disease 76%
  • Cardiomyopathies 61%
  • Connectin 36%
  186 Scopus citations
• 2014

  Incidence and clinical characteristics of takotsubo cardiomyopathy post-aneurysmal subarachnoid hemorrhage

  Abd, T. T., Hayek, S., Cheng, J. W., Samuels, O. B., Wittstein, I. S. & Lerakis, S., Oct 20 2014, In: International Journal of Cardiology. 176, 3, p. 1362-1364 3 p.

  Research output: Contribution to journal › Article › peer-review
  33 Scopus citations

• Mechanical alternans is associated with mortality in acute hospitalized heart failure prospective mechanical alternans study (mas)

  Kim, R., Cingolani, O., Wittstein, I., McLean, R., Han, L., Cheng, K., Robinson, E., Brinker, J., Schulman, S. S., Berger, R. D., Henrikson, C. A. & Tereshchenko, L. G., Apr 2014, In: Circulation: Arrhythmia and Electrophysiology. 7, 2, p. 259-266 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • alternan 100%
  • Heart Failure 50%
  • Mortality 35%
  • Heart 8%
  • Confidence Intervals 7%
  12 Scopus citations

• Post-discharge prognosis of stress cardiomyopathy in women: A retrospective cohort study

  Salmoirago-Blotcher, E., Reddy, S., Swales, H., Wittstein, I., Ockene, I., Aurigemma, G., Bouchard, J. & Goldberg, R. J., Sep 1 2014, In: IJC Metabolic and Endocrine. 4, p. 23-27 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Takotsubo Cardiomyopathy 100%
  • Cohort Studies 49%
  • Retrospective Studies 48%
  • ST Elevation Myocardial Infarction 40%
  • Incidence 8%
• 2013

  Is abnormal myocardial repolarization associated with the occurrence of malignant tachyarrhythmias in Takotsubo cardiomyopathy?

  Streitner, F., Hamm, K., Wittstein, I. S., Baranchuk, A., Akashi, Y. J., Nef, H. M., Bonello, L., Wolpert, C., Borggrefe, M. & Haghi, D., 2013, In: Cardiology Journal. 20, 6, p. 633-638 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Takotsubo Cardiomyopathy 100%
  • Tachycardia 70%
  • Lead 66%
  • Syncope 47%
  • Torsades de Pointes 38%
  3 Scopus citations
• 2012

  Left ventricular assist device support and myocardial recovery in recent onset cardiomyopathy

  Boehmer, J. P., Starling, R. C., Cooper, L. T., Torre-Amione, G., Wittstein, I., Dec, G. W., Markham, D. W., Zucker, M. J., Gorcsan, J., McTiernan, C., Kip, K. & McNamara, D. M., Oct 1 2012, In: Journal of cardiac failure. 18, 10, p. 755-761 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Heart-Assist Devices 100%
  • Cardiomyopathies 82%
  • Myocarditis 19%
  • Registries 13%
  • Histology 13%
  43 Scopus citations

• Myocardial recovery in peripartum cardiomyopathy: Prospective comparison with recent onset cardiomyopathy in men and nonperipartum women

  Cooper, L. T., Mather, P. J., Alexis, J. D., Pauly, D. F., Torre-Amione, G., Wittstein, I. S., Dec, G. W., Zucker, M., Narula, J., Kip, K. & McNamara, D. M., Jan 2012, In: Journal of cardiac failure. 18, 1, p. 28-33 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Peripartum Period 100%
  • Cardiomyopathies 73%
  • Stroke Volume 29%
  • Myocarditis 24%
  • Dilated Cardiomyopathy 11%
  63 Scopus citations

• Stress cardiomyopathy: A syndrome of catecholamine-mediated myocardial stunning?

  Wittstein, I. S., Jul 2012, In: Cellular and molecular neurobiology. 32, 5, p. 847-857 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Myocardial Stunning 100%
  • Takotsubo Cardiomyopathy 96%
  • Catecholamines 65%
  • Left Ventricular Dysfunction 21%
  • Coronary Thrombosis 14%
  109 Scopus citations

• The variable natural history of idiopathic dilated cardiomyopathy

  Parakh, K., Kittleson, M. M., Heidecker, B., Wittstein, I. S., Judge, D. P., Champion, H. C., Barouch, L. A., Baughman, K. L., Russell, S. D., Kasper, E. K., Sitammagari, K. K. & Hare, J. M., 2012, In: Israel Medical Association Journal. 14, 11, p. 666-671 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Dilated Cardiomyopathy 100%
  • Survivors 14%
  • Heart Failure 12%
  • Heart-Assist Devices 9%
  • Angiotensin Receptor Antagonists 9%
  5 Scopus citations
• 2011

  Capnocytophagia canimorsus sepsis in an asplenic heart transplant candidate with a left ventricular assist system

  Ensor, C. R., Russell, S. D., Wittstein, I. S. & Conte, J. V., Jun 1 2011, In: Progress in Transplantation. 21, 2, p. 121-123 3 p.

  Research output: Contribution to journal › Article › peer-review

  • sultamicillin 100%
  • Bites and Stings 76%
  • Heart Transplantation 74%
  • Septic Shock 72%
  • Bacteremia 71%
  2 Scopus citations

• Transcriptomic biomarkers for the accurate diagnosis of myocarditis

  Heidecker, B., Kittleson, M. M., Kasper, E. K., Wittstein, I. S., Champion, H. C., Russell, S. D., Hruban, R. H., Rodriguez, E. R., Baughman, K. L. & Hare, J. M., Mar 22 2011, In: Circulation. 123, 11, p. 1174-1184 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Myocarditis 100%
  • Transcriptome 61%
  • Biomarkers 57%
  • Dilated Cardiomyopathy 48%
  • Cardiomyopathies 43%
  54 Scopus citations
• 2010

  The gene expression profile of patients with new-onset heart failure reveals important gender-specific differences

  Heidecker, B., Lamirault, G., Kasper, E. K., Wittstein, I. S., Champion, H. C., Breton, E., Russell, S. D., Hall, J., Kittleson, M. M., Baughman, K. L. & Hare, J. M., May 2010, In: European heart journal. 31, 10, p. 1188-1196 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Transcriptome 100%
  • Heart Failure 79%
  • Dilated Cardiomyopathy 59%
  • X-linked zinc finger protein 55%
  • Y Chromosome 32%
  59 Scopus citations
• 2009

  Stress Cardiomyopathy After Intravenous Administration of Catecholamines and Beta-Receptor Agonists

  Abraham, J., Mudd, J. O., Kapur, N., Klein, K., Champion, H. C. & Wittstein, I. S., Apr 14 2009, In: Journal of the American College of Cardiology. 53, 15, p. 1320-1325 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Catecholamine Receptors 100%
  • Takotsubo Cardiomyopathy 84%
  • Intravenous Administration 57%
  • Dobutamine 15%
  • Troponin I 14%
  282 Scopus citations

• The Change in B-Type Natriuretic Peptide Levels Over Time Predicts Significant Rejection in Cardiac Transplant Recipients

  Kittleson, M. M., Skojec, D. V., Wittstein, I. S., Champion, H. C., Judge, D. P., Barouch, L. A., Halushka, M., Hare, J. M., Kasper, E. K. & Russell, S. D., Jul 2009, In: Journal of Heart and Lung Transplantation. 28, 7, p. 704-709 6 p.

  Research output: Contribution to journal › Article › peer-review

  • pro-brain natriuretic peptide (1-76) 100%
  • Brain Natriuretic Peptide 83%
  • Transplant Recipients 70%
  • Odds Ratio 27%
  • Confidence Intervals 19%
  26 Scopus citations
• 2008

  PDE5A inhibitor treatment of persistent pulmonary hypertension after mechanical circulatory support.

  Tedford, R., Hemnes, A. R., Russell, S., Wittstein, I. S., Mahmud, M., Zaiman, A. L., Mathai, S. C., Thiemann, D. R., Hassoun, P. M., Girgis, R., Orens, J. B., Shah, A. S., Yuh, D. D., Conte, J. V. & Champion, H. C., Nov 2008, In: Circulation. Heart failure. 1, 4, p. 213-219 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Pulmonary Hypertension 100%
  • Heart-Assist Devices 92%
  • Sildenafil Citrate 70%
  • Vascular Resistance 52%
  • Type 5 Cyclic Nucleotide Phosphodiesterases 48%
  121 Scopus citations

• Transcriptomic biomarkers for individual risk assessment in new-onset heart failure

  Heidecker, B., Kasper, E. K., Wittstein, I. S., Champion, H. C., Breton, E., Russell, S. D., Kittleson, M. M., Baughman, K. L. & Hare, J. M., Jul 15 2008, In: Circulation. 118, 3, p. 238-246 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Risk Assessment 100%
  • Heart Failure 87%
  • Biomarkers 78%
  • Microarray Analysis 61%
  • Biopsy 48%
  73 Scopus citations
• 2007

  Elevated Uric Acid Levels Predict Allograft Vasculopathy in Cardiac Transplant Recipients

  Kittleson, M. M., Bead, V., Fradley, M., St. John, M. E., Champion, H. C., Kasper, E. K., Russell, S. D., Wittstein, I. S. & Hare, J. M., May 2007, In: Journal of Heart and Lung Transplantation. 26, 5, p. 498-503 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Uric Acid 100%
  • Transplant Recipients 91%
  • Allografts 86%
  • Odds Ratio 36%
  • Hyperuricemia 34%
  12 Scopus citations

• Increased levels of uric acid predict haemodynamic compromise in patients with heart failure independently of B-type natriuretic peptide levels

  Kittleson, M. M., St. John, M. E., Bead, V., Champion, H. C., Kasper, E. K., Russell, S. D., Wittstein, I. S. & Hare, J. M., Mar 2007, In: Heart. 93, 3, p. 365-367 3 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  46 Scopus citations

• Spiritual well-being and depression in patients with heart failure

  Bekelman, D. B., Dy, S. M., Becker, D. M., Wittstein, I. S., Hendricks, D. E., Yamashita, T. E. & Gottlieb, S. H., Apr 2007, In: Journal of general internal medicine. 22, 4, p. 470-477 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Heart Failure 100%
  • Geriatrics 43%
  • Spiritual Therapies 36%
  • Quality of Life 29%
  • Social Support 21%
  128 Scopus citations

• Successful management of an unruptured mycotic coronary aneurysm

  Kapur, N. K., Conte, J. V. & Wittstein, I. S., Dec 1 2007, In: Journal of Invasive Cardiology. 19, 12, p. E366-E368

  Research output: Contribution to journal › Article › peer-review

  • Infected Aneurysm 100%
  • Coronary Aneurysm 98%
  • Transesophageal Echocardiography 79%
  • Endocarditis 49%
  • Embolism 24%
  5 Scopus citations

• Symptoms, Depression, and Quality of Life in Patients With Heart Failure

  Bekelman, D. B., Havranek, E. P., Becker, D. M., Kutner, J. S., Peterson, P. N., Wittstein, I. S., Gottlieb, S. H., Yamashita, T. E., Fairclough, D. L. & Dy, S. M., Oct 2007, In: Journal of cardiac failure. 13, 8, p. 643-648 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Heart Failure 100%
  • Quality of Life 88%
  • peptide P 24%
  • Symptom Assessment 19%
  • Brain Natriuretic Peptide 18%
  211 Scopus citations

• The broken heart syndrome

  Wittstein, I. S., 2007, In: Cleveland Clinic journal of medicine. 74, SUPPL.1, p. 17-22 6 p.

  Research output: Contribution to journal › Article › peer-review
  20 Scopus citations
• 2006

  Left insular stroke is associated with adverse cardiac outcome

  Laowattana, S., Zeger, S. L., Lima, J. A. C., Goodman, S. N., Wittstein, I. S. & Oppenheimer, S. M., Feb 2006, In: Neurology. 66, 4, p. 477-483 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Stroke 100%
  • Coronary Artery Disease 60%
  • Ischemic Preconditioning 23%
  • Transesophageal Echocardiography 20%
  • Cardiac Arrhythmias 15%
  130 Scopus citations
• 2005

  Neurohumoral features of myocardial stunning due to sudden emotional stress

  Wittstein, I. S., Thiemann, D. R., Lima, J. A. C., Baughman, K. L., Schulman, S. P., Gerstenblith, G., Wu, K. C., Rade, J. J., Bivalacqua, T. J. & Champion, H. C., Feb 10 2005, In: New England Journal of Medicine. 352, 6, p. 539-548 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Myocardial Stunning 100%
  • Psychological Distress 70%
  • Left Ventricular Dysfunction 30%
  • Takotsubo Cardiomyopathy 19%
  • Catecholamines 13%
  2172 Scopus citations

• Transient left ventricular apical ballooning: Magnetic resonance imaging evaluation

  Fritz, J., Wittstein, I. S., Lima, J. A. C. & Bluemke, D. A., 2005, In: Journal of computer assisted tomography. 29, 1, p. 34-36 3 p.

  Research output: Contribution to journal › Article › peer-review

  • Myocardial Infarction 100%
  • Magnetic Resonance Imaging 91%
  22 Scopus citations
• 2003

  Images in cardiovascular medicine. ST-segment elevation in an unresponsive patient.

  Hirsch, G. A., Heldman, A. W., Wittstein, I. S., Schulman, S. P. & Gerstenblith, G., Dec 16 2003, In: Circulation. 108, 24, p. e165-166

  Research output: Contribution to journal › Article › peer-review
  6 Scopus citations
• 2001

  Cardiac nitric oxide production due to angiotensin-converting enzyme inhibition decreases beta-adrenergic myocardial contractility in patients with dilated cardiomyopathy

  Wittstein, I. S., Kass, D. A., Pak, P. H., Maughan, W. L., Fetics, B. & Hare, J. M., 2001, In: Journal of the American College of Cardiology. 38, 2, p. 429-435 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Enalaprilat 100%
  • Peptidyl-Dipeptidase A 71%
  • Dilated Cardiomyopathy 71%
  • Adrenergic Agents 63%
  • Nitric Oxide 53%
  42 Scopus citations
• 2000

  In vitro system to study realistic pulsatile flow and stretch signaling in cultured vascular cells

  Peng, X., Recchia, F. A., Byrne, B. J., Wittstein, I. S., Ziegelstein, R. C. & Kass, D. A., 2000, In: American Journal of Physiology - Cell Physiology. 279, 3 48-3, p. C797-C805

  Research output: Contribution to journal › Article › peer-review

  • Pulsatile Flow 100%
  • Cultured Cells 62%
  • Pressure 48%
  • Blood Vessels 43%
  • Arterial Pressure 40%
  64 Scopus citations

• Opposite effects of pressurized steady versus pulsatile perfusion on vascular endothelial cell cytosolic pH: Role of tyrosine kinase and mitogen- activated protein kinase signaling

  Wittstein, I. S., Qiu, W., Ziegelstein, R. C., Hu, Q. & Kass, D. A., Jun 23 2000, In: Circulation research. 86, 12, p. 1230-1236 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Pulsatile Flow 100%
  • Mitogen-Activated Protein Kinases 73%
  • Protein-Tyrosine Kinases 67%
  • Endothelial Cells 55%
  • CSK Tyrosine-Protein Kinase 24%
  16 Scopus citations
• 1993

  A Novel Therapy for Myasthenia Gravis by Reducing the Endocytosis of Acetylcholine Receptors

  KUNCL, RALPH. W., WITTSTEIN, ILAN., ADAMS, ROBERT. N., WIGGINS, WINSTON. W., AVILA, ORLANDO., PESTRONK, ALAN., McINTOSH, KEVIN., LUCAS, DONNA., DESILVA, SHARI., LEHAR, MOHAMED. & DRACHMAN, DANIEL. B., Jun 1993, In: Annals of the New York Academy of Sciences. 681, 1, p. 298-302 5 p.

  Research output: Contribution to journal › Article › peer-review
  4 Scopus citations