Heeseong Jang

2023

Epoxyeicosatrienoic acid administration or soluble epoxide hydrolase inhibition attenuates renal fibrogenesis in obstructive nephropathy

Noh, M. R., Jang, H. S., Salem, F. E., Ferrer, F. A., Kim, J. & Padanilam, B. J., Feb 2023, In: American Journal of Physiology - Renal Physiology. 324, 2, p. F138-F151

Research output: Contribution to journal › Article › peer-review

Human milk oligosaccharides reduce necrotizing enterocolitis-induced neuroinflammation and cognitive impairment in mice

Sodhi, C. P., Ahmad, R., Fulton, W. B., Lopez, C. M., Eke, B. O., Scheese, D., Duess, J. W., Steinway, S. N., Raouf, Z., Moore, H., Tsuboi, K., Sampah, M. E., Jang, H. S., Buck, R. H., Hill, D. R., Niemiro, G. M., Prindle, T., Wang, S., Wang, M., Jia, H., & 3 othersCatazaro, J., Lu, P. & Hackam, D. J., Jul 2023, In: American Journal of Physiology - Gastrointestinal and Liver Physiology. 325, 1, p. G23-G41

Research output: Contribution to journal › Article › peer-review

2022

2-Mercaptoethanol protects against DNA double-strand breaks after kidney ischemia and reperfusion injury through GPX4 upregulation

Moon, D., Padanilam, B. J., Jang, H. S. & Kim, J., Oct 2022, In: Pharmacological Reports. 74, 5, p. 1041-1053 13 p.

Research output: Contribution to journal › Article › peer-review

Hepatic and proximal tubule angiotensinogen play distinct roles in kidney dysfunction, glomerular and tubular injury, and fibrosis progression

Jang, H. S., Noh, M. R., Plumb, T., Lee, K., He, J. C., Ferrer, F. A. & Padanilam, B. J., Oct 1 2022, In: American Journal of Physiology - Renal Physiology. 323, 4, p. F435-F446

Research output: Contribution to journal › Article › peer-review

Modified chitosan for effective renal delivery of siRNA to treat acute kidney injury

Tang, W., Panja, S., Jogdeo, C. M., Tang, S., Ding, L., Yu, A., Foster, K. W., Dsouza, D. L., Chhonker, Y. S., Jensen-Smith, H., Jang, H. S., Boesen, E. I., Murry, D. J., Padanilam, B. & Oupický, D., Jun 2022, In: Biomaterials. 285, 121562.

Research output: Contribution to journal › Article › peer-review

Open Access

Preferential siRNA delivery to injured kidneys for combination treatment of acute kidney injury

Tang, W., Chen, Y., Jang, H. S., Hang, Y., Jogdeo, C. M., Li, J., Ding, L., Zhang, C., Yu, A., Yu, F., Foster, K. W., Padanilam, B. J. & Oupický, D., Jan 2022, In: Journal of Controlled Release. 341, p. 300-313 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2021

IDH2 gene deficiency accelerates unilateral ureteral obstruction-induced kidney inflammation through oxidative stress and activation of macrophages

Kim, J. I., Noh, M. R., Yoon, G. E., Jang, H. S., Kong, M. J. & Park, K. M., Mar 2021, In: Korean Journal of Physiology and Pharmacology. 25, 2, p. 139-146 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Proximal tubule cyclophilin D mediates kidney fibrogenesis in obstructive nephropathy

Jang, H. S., Noh, M. R., Ha, L., Kim, J. & Padanilam, B. J., Oct 2021, In: American Journal of Physiology - Renal Physiology. 321, 4, p. F431-F442

Research output: Contribution to journal › Article › peer-review

Open Access

Role of α- and β-adrenergic signaling in phenotypic targeting: significance in benign and malignant urologic disease

Archer, M., Dogra, N., Dovey, Z., Ganta, T., Jang, H. S., Khusid, J. A., Lantz, A., Mihalopoulos, M., Stockert, J. A., Zahalka, A., Björnebo, L., Gaglani, S., Noh, M. R., Kaplan, S. A., Mehrazin, R., Badani, K. K., Wiklund, P., Tsao, K., Lundon, D. J., Mohamed, N., & 5 othersLucien, F., Padanilam, B., Gupta, M., Tewari, A. K. & Kyprianou, N., Dec 2021, In: Cell Communication and Signaling. 19, 1, 78.

Research output: Contribution to journal › Review article › peer-review

Open Access

2020

Defective Mitochondrial Fatty Acid Oxidation and Lipotoxicity in Kidney Diseases

Jang, H. S., Noh, M. R., Kim, J. & Padanilam, B. J., Mar 12 2020, In: Frontiers in Medicine. 7, 65.

Research output: Contribution to journal › Review article › peer-review

Open Access

Nephron progenitor maintenance is controlled through fibroblast growth factors and sprouty1 interaction

Huh, S. H., Ha, L. & Jang, H. S., Nov 2020, In: Journal of the American Society of Nephrology. 31, 11, p. 2559-2572 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Proximal tubule cyclophilin D regulates fatty acid oxidation in cisplatin-induced acute kidney injury

Jang, H. S., Noh, M. R., Jung, E. M., Kim, W. Y., Southekal, S., Guda, C., Foster, K. W., Oupicky, D., Ferrer, F. A. & Padanilam, B. J., Feb 2020, In: Kidney international. 97, 2, p. 327-339 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Renal sympathetic nerve-derived signaling in acute and chronic kidney diseases

Noh, M. R., Jang, H. S., Kim, J. & Padanilam, B. J., Mar 2020, In: International journal of molecular sciences. 21, 5, 1647.

Research output: Contribution to journal › Review article › peer-review

Open Access

2019

Determinants of preferential renal accumulation of synthetic polymers in acute kidney injury

Chen, Y., Tang, W., Yu, F., Xie, Y., Jaramillo, L., Jang, H. S., Li, J., Padanilam, B. J. & Oupický, D., Sep 10 2019, In: International Journal of Pharmaceutics. 568, 118555.

Research output: Contribution to journal › Article › peer-review

Renal sympathetic nerve activation via α₂-adrenergic receptors in chronic kidney disease progression

Jang, H. S., Kim, J. & Padanilam, B. J., Mar 2019, In: Kidney Research and Clinical Practice. 38, 1, p. 6-14 9 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

2018

Downregulation of exocyst Sec10 accelerates kidney tubule cell recovery through enhanced cell migration

Noh, M. R., Jang, H. S., Song, D. K., Lee, S. R., Lipschutz, J. H., Park, K. M. & Kim, J. I., Feb 5 2018, In: Biochemical and Biophysical Research Communications. 496, 2, p. 309-315 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2017

Hepatic ischemia/reperfusion injury disrupts the homeostasis of kidney primary cilia via oxidative stress

Han, S. J., Jang, H. S., Seu, S. Y., Cho, H. J., Hwang, Y. J., Kim, J. I. & Park, K. M., Jul 2017, In: Biochimica et Biophysica Acta - Molecular Basis of Disease. 1863, 7, p. 1817-1828 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Mitochondrial NADP+-dependent isocitrate dehydrogenase deficiency exacerbates mitochondrial and cell damage after kidney ischemia-reperfusion injury

Han, S. J., Jang, H. S., Noh, M. R., Kim, J., Kong, M. J., Kim, J. I., Park, J. W. & Park, K. M., Apr 2017, In: Journal of the American Society of Nephrology. 28, 4, p. 1200-1215 16 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2016

Smooth muscle-generated methylglyoxal impairs endothelial cell-mediated vasodilatation of cerebral microvessels in type 1 diabetic rats

Alomar, F., Singh, J., Jang, H. S., Rozanzki, G. J., Shao, C. H., Padanilam, B. J., Mayhan, W. G. & Bidasee, K. R., 2016, In: British Journal of Pharmacology. 173, 23, p. 3307-3326 20 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Unilateral nephrectomy elongates primary cilia in the remaining kidney via reactive oxygen species

Han, S. J., Jang, H. S., Kim, J. I., Lipschutz, J. H. & Park, K. M., Feb 29 2016, In: Scientific reports. 6, 22281.

Research output: Contribution to journal › Article › peer-review

Open Access

2015

CD169⁺ macrophages: Regulators of neutrophil trafficking to injured kidneys

Jang, H. S., Rabb, H. & Padanilam, B. J., Apr 1 2015, In: Journal of the American Society of Nephrology. 26, 4, p. 769-771 3 p.

Research output: Contribution to journal › Editorial › peer-review

Open Access

Methionine sulfoxide reductase A deficiency exacerbates progression of kidney fibrosis induced by unilateral ureteral obstruction

Kim, J. I., Noh, M. R., Kim, K. Y., Jang, H. S., Kim, H. Y. & Park, K. M., Dec 1 2015, In: Free Radical Biology and Medicine. 89, p. 201-208 8 p.

Research output: Contribution to journal › Article › peer-review

Simultaneous deletion of bax and bak is required to prevent apoptosis and interstitial fibrosis in obstructive nephropathy

Jang, H. S. & Padanilam, B. J., Sep 15 2015, In: American Journal of Physiology - Renal Physiology. 309, 6, p. F540-F550

Research output: Contribution to journal › Article › peer-review

2014

Angiotensin II Removes Kidney Resistance Conferred by Ischemic Preconditioning

Jang, H. S., Kim, J. I., Kim, J., Park, J. W. & Park, K. M., 2014, In: BioMed research international. 2014, 602149.

Research output: Contribution to journal › Article › peer-review

Open Access

Recruitment and subsequent proliferation of bone marrow-derived cells in the postischemic kidney are important to the progression of fibrosis

Jang, H. S., Kim, J. I., Han, S. J. & Park, K. M., Jun 15 2014, In: American Journal of Physiology - Renal Physiology. 306, 12, p. F1451-F1461

Research output: Contribution to journal › Article › peer-review

Regulator of G protein signaling 2 (RGS2) deficiency accelerates the progression of kidney fibrosis

Jang, H. S., Kim, J. I., Noh, M., Rhee, M. H. & Park, K. M., Sep 2014, In: Biochimica et Biophysica Acta - Molecular Basis of Disease. 1842, 9, p. 1733-1741 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2013

Activation of ERK accelerates repair of renal tubular epithelial cells, whereas it inhibits progression of fibrosis following ischemia/reperfusion injury

Jang, H. S., Han, S. J., Kim, J. I., Lee, S., Lipschutz, J. H. & Park, K. M., 2013, In: Biochimica et Biophysica Acta - Molecular Basis of Disease. 1832, 12, p. 1998-2008 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Bone marrow-derived cells play a major role in kidney fibrosis via proliferation and differentiation in the infiltrated site

Jang, H. S., Kim, J. I., Jung, K. J., Kim, J., Han, K. H. & Park, K. M., Jun 2013, In: Biochimica et Biophysica Acta - Molecular Basis of Disease. 1832, 6, p. 817-825 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Defect in Runx2 gene accelerates ureteral obstruction-induced kidney fibrosis via increased TGF-β signaling pathway

Kim, J. I., Jang, H. S., Jeong, J. H., Noh, M. R., Choi, J. Y. & Park, K. M., Oct 2013, In: Biochimica et Biophysica Acta - Molecular Basis of Disease. 1832, 10, p. 1520-1527 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Gender-specific role of HDAC11 in kidney ischemia- and reperfusion-induced PAI-1 expression and injury

Kim, J. I., Jung, K. J., Jang, H. S. & Park, K. M., Jul 1 2013, In: American Journal of Physiology - Renal Physiology. 305, 1, p. F61-F70

Research output: Contribution to journal › Article › peer-review

Involvement of hydrogen sulfide and homocysteine transsulfuration pathway in the progression of kidney fibrosis after ureteral obstruction

Jung, K. J., Jang, H. S., Kim, J. I., Han, S. J., Park, J. W. & Park, K. M., 2013, In: Biochimica et Biophysica Acta - Molecular Basis of Disease. 1832, 12, p. 1989-1997 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Reduction of oxidative stress during recovery accelerates normalization of primary cilia length that is altered after ischemic injury in murine kidneys

Kim, J. I., Kim, J., Jang, H. S., Noh, M. R., Lipschutz, J. H. & Park, K. M., 2013, In: American Journal of Physiology - Renal Physiology. 304, 10, p. 1283-1294 12 p.

Research output: Contribution to journal › Article › peer-review

2012

Bone marrow derived cells and reactive oxygen species in hypertrophy of contralateral kidney of transient unilateral renal ischemia-induced mouse

Jang, H. S., Kim, J. I., Kim, J., Na, Y. K., Park, J. W. & Park, K. M., Jul 2012, In: Free Radical Research. 46, 7, p. 903-911 9 p.

Research output: Contribution to journal › Article › peer-review

Orchiectomy attenuates kidney fibrosis after ureteral obstruction by reduction of oxidative stress in mice

Cho, M. H., Jung, K. J., Jang, H. S., Kim, J. I. & Park, K. M., Jan 2012, In: American Journal of Nephrology. 35, 1, p. 7-16 10 p.

Research output: Contribution to journal › Article › peer-review

Previous ischemia and reperfusion injury results in resistance of the kidney against subsequent ischemia and reperfusion insult in mice; A role for the Akt signal pathway

Jang, H. S., Kim, J., Kim, K. Y., Kim, J. I., Cho, M. H. & Park, K. M., Oct 2012, In: Nephrology Dialysis Transplantation. 27, 10, p. 3762-3770 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2011

Evaluation of kidney repair capacity using 99mTc-DMSA in ischemia/reperfusion injury models

Kwak, W., Jang, H. S., Belay, T., Kim, J., Ha, Y. S., Lee, S. W., Ahn, B. C., Lee, J., Park, K. M. & Yoo, J., Mar 4 2011, In: Biochemical and Biophysical Research Communications. 406, 1, p. 7-12 6 p.

Research output: Contribution to journal › Article › peer-review

Protective role of cytosolic NADP ⁺-dependent isocitrate dehydrogenase, IDH1, in ischemic pre-conditioned kidney in mice

Kim, J., Kim, J. I., Jang, H. S., Park, J. W. & Park, K. M., Jul 2011, In: Free Radical Research. 45, 7, p. 759-766 8 p.

Research output: Contribution to journal › Article › peer-review

2010

Endotoxin-induced renal tolerance against ischemia and reperfusion injury is removed by iNOS, but not eNOS, gene-deletion

Kim, J. I., Jang, H. S. & Park, K. M., Sep 2010, In: BMB Reports. 43, 9, p. 629-634 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Reactive oxygen species generated by renal ischemia and reperfusion trigger protection against subsequent renal ischemia and reperfusion injury in mice

Kim, J., Jang, H. S. & Park, K. M., Jan 2010, In: American Journal of Physiology - Renal Physiology. 298, 1, p. F158-F166

Research output: Contribution to journal › Article › peer-review

2009

Role of cytosolic NADP⁺-dependent isocitrate dehydrogenase in ischemia-reperfusion injury in mouse kidney

Kim, J., Ki, Y. K., Jang, H. S., Yoshida, T., Tsuchiya, K., Nitta, K., Park, J. W., Bonventre, J. V. & Park, K. M., Mar 2009, In: American Journal of Physiology - Renal Physiology. 296, 3, p. F622-F633

Research output: Contribution to journal › Article › peer-review

Open Access

2008

Infiltrated macrophages contribute to recovery after ischemic injury but not to ischemic preconditioning in kidneys

Jang, H. S., Kim, J., Park, Y. K. & Park, K. M., Feb 2008, In: Transplantation. 85, 3, p. 447-455 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Heeseong Jang

Research output

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