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Dive into the research topics where Gregg Semenza is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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HIF-1-mediated ISG20 expression promotes breast cancer stemness and immune evasion
Yang, Y., Zuo, Q., Ramu, V., Talwar, V., Lyu, Y., Chen, C., Drehmer, D., Yi-Ting Huang, T., Salman, S., Dordai, D., Wang, Y., Datan, E., Wicks, E. E. & Semenza, G. L., Mar 2 2026, In: The Journal of experimental medicine. 223, 3Research output: Contribution to journal › Article › peer-review
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Corrigendum: FIH-1: a novel protein that interacts with HIF-1α and VHL to mediate repression of HIF-1 transcriptional activity
Mahon, P. C., Hirota, K. & Semenza, G. L., 2025, In: Genes and Development. 39, 13-14Research output: Contribution to journal › Comment/debate › peer-review
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Development of small molecule inhibitors of hypoxia-inducible factors for cancer therapy
Semenza, G. L., Sep 2025, In: Pharmacological reviews. 77, 5, 100075.Research output: Contribution to journal › Review article › peer-review
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HIF-1 promotes murine breast cancer brain metastasis by increasing production of integrin β3–containing extracellular vesicles
Yang, Y., Chen, C., Lyu, Y., Gololobova, O., Guo, X., Huang, T. Y. T., Ramu, V., Talwar, V., Wicks, E. E., Salman, S., Drehmer, D., Dordai, D., Zuo, Q., Witwer, K. W., Gabrielson, K. L. & Semenza, G. L., Jul 15 2025, In: Journal of Clinical Investigation. 135, 14, e190470.Research output: Contribution to journal › Article › peer-review
Open Access -
Retraction: Nitric Oxide Induces Hypoxia-inducible Factor 1 Activation That Is Dependent on MAPK and Phosphatidylinositol 3-Kinase Signaling (Journal of Biological Chemistry (2004) 279(4) (2550–2558), (S0021925818526193), (10.1074/jbc.M308197200))
Kasuno, K., Takabuchi, S., Fukuda, K., Kizaka-Kondoh, S., Yodoi, J., Adachi, T., Semenza, G. L. & Hirota, K., Jul 2025, In: Journal of Biological Chemistry. 301, 7, 110219.Research output: Contribution to journal › Comment/debate › peer-review
Open Access