Elizabeth Thompson

2024

COVID-19 vaccination induces distinct T-cell responses in pediatric solid organ transplant recipients and immunocompetent children

Roznik, K., Xue, J., Stavrakis, G., Johnston, T. S., Kalluri, D., Ohsie, R., Qin, C. X., McAteer, J., Segev, D. L., Mogul, D. B., Werbel, W. A., Karaba, A. H., Thompson, E. & Cox, A., Dec 2024, In: npj Vaccines. 9, 1, 73.

Research output: Contribution to journal › Article › peer-review

Open Access

2023

Heterologous versus homologous boosting elicits qualitatively distinct, BA.5–crossreactive T cells in transplant recipients

Thompson, E. A., Ngecu, W., Stoddart, L., Johnston, T. S., Chang, A., Cascino, K., Alejo, J. L., Abedon, A. T., Samaha, H., Rouphael, N., Tobian, A. A. R., Segev, D. L., Werbel, W. A., Karaba, A. H., Blankson, J. N. & Cox, A. L., May 8 2023, In: JCI Insight. 8, 10, e168470.

Research output: Contribution to journal › Article › peer-review

Open Access

Impact of Seasonal Coronavirus Antibodies on Severe Acute Respiratory Syndrome Coronavirus 2 Vaccine Responses in Solid Organ Transplant Recipients

Karaba, A. H., Zhou, W., Li, S., Aytenfisu, T. Y., Johnston, T. S., Akinde, O., Eby, Y., Abedon, A. T., Alejo, J. L., Qin, C. X., Thompson, E. A., Garonzik-Wang, J. M., Blankson, J. N., Cox, A. L., Bailey, J. R., Klein, S. L., Pekosz, A., Segev, D. L., Tobian, A. A. R. & Werbel, W. A., Feb 1 2023, In: Clinical Infectious Diseases. 76, 3, p. E495-E498

Research output: Contribution to journal › Article › peer-review

Open Access

Multivalent antigen display on nanoparticle immunogens increases B cell clonotype diversity and neutralization breadth to pneumoviruses

Ols, S., Lenart, K., Arcoverde Cerveira, R., Miranda, M. C., Brunette, N., Kochmann, J., Corcoran, M., Skotheim, R., Philomin, A., Cagigi, A., Fiala, B., Wrenn, S., Marcandalli, J., Hellgren, F., Thompson, E. A., Lin, A., Gegenfurtner, F., Kumar, A., Chen, M., Phad, G. E., & 7 othersGraham, B. S., Perez, L., Borst, A. J., Karlsson Hedestam, G. B., Ruckwardt, T. J., King, N. P. & Loré, K., Oct 10 2023, In: Immunity. 56, 10, p. 2425-2441.e14

Research output: Contribution to journal › Article › peer-review

Open Access

Persistent SARS-CoV-2–specific immune defects in kidney transplant recipients following third mRNA vaccine dose

CPAT investigators, Jun 2023, In: American Journal of Transplantation. 23, 6, p. 744-758 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Progress in vaccine development for infectious diseases-a Keystone Symposia report

Cable, J., Graham, B. S., Koup, R. A., Seder, R. A., Karikó, K., Pardi, N., Barouch, D. H., Sharma, B., Rauch, S., Nachbagauer, R., Forsell, M. N. E., Schotsaert, M., Ellebedy, A. H., Loré, K., Irvine, D. J., Pilkington, E., Tahtinen, S., Thompson, E. A., Feraoun, Y., King, N. P., & 19 othersSaunders, K., Alter, G., Moin, S. M., Sliepen, K., Karlsson Hedestam, G. B., Wardemann, H., Pulendran, B., Doria-Rose, N. A., He, W. T., Juno, J. A., Ataca, S., Wheatley, A. K., McLellan, J. S., Walker, L. M., Lederhofer, J., Lindesmith, L. C., Wille, H., Hotez, P. J. & Bekker, L. G., Jun 1 2023, In: Annals of the New York Academy of Sciences. 1524, 1, p. 65-86 22 p.

Research output: Contribution to journal › Article › peer-review

T cell metabolic reprogramming in acute kidney injury and protection by glutamine blockade

Lee, K., Thompson, E. A., Gharaie, S., Patel, C. H., Kurzhagen, J. T., Pierorazio, P. M., Arend, L. J., Thomas, A. G., Noel, S., Slusher, B. S. & Rabb, H., 2023, In: JCI Insight. 8, 12, e160345.

Research output: Contribution to journal › Article › peer-review

Open Access

Three doses of COVID-19 mRNA vaccine induce class-switched antibody responses in inflammatory arthritis patients on immunomodulatory therapies

Lee, J. M., Figueroa, A., Sachithanandham, J., Li, M., Connolly, C. M., Shapiro, J. R., Chen, Y., Jones, M., Dhara, V. G., Towns, M., Lee, J. S., Peralta, S. R., Milstone, A. M., Betenbaugh, M., Debes, A. K., Blankson, J., Sitaras, I., Yoon, S., Thompson, E. A., Bingham, C. O., & 3 othersKlein, S. L., Pekosz, A. & Bailey, J. R., 2023, In: Frontiers in immunology. 14, 1266370.

Research output: Contribution to journal › Article › peer-review

Open Access

2022

A common framework of monocyte-derived macrophage activation

Sanin, D. E., Ge, Y., Marinkovic, E., Kabat, A. M., Castoldi, A., Caputa, G., Grzes, K. M., Curtis, J. D., Thompson, E. A., Willenborg, S., Dichtl, S., Reinhardt, S., Dahl, A., Pearce, E. L., Eming, S. A., Gerbaulet, A., Roers, A., Murray, P. J. & Pearce, E. J., Apr 2022, In: Science Immunology. 7, 70, abl7482.

Research output: Contribution to journal › Article › peer-review

Androgen receptor activity in prostate cancer dictates efficacy of bipolar androgen therapy through MYC

Sena, L. A., Kumar, R., Sanin, D. E., Thompson, E. A., Rosen, D. M., Dalrymple, S. L., Antony, L., Yang, Y., Gomes-Alexandre, C., Hicks, J. L., Jones, T., Bowers, K. A., Eskra, J. N., Meyers, J., Gupta, A., Skaist, A., Yegnasubramanian, S., Luo, J., Brennen, W. N., Kachhap, S. K., & 5 othersAntonarakis, E. S., De Marzo, A. M., Isaacs, J. T., Markowski, M. C. & Denmeade, S. R., Dec 1 2022, In: Journal of Clinical Investigation. 132, 23, e162396.

Research output: Contribution to journal › Article › peer-review

Open Access

A third dose of SARS-CoV-2 vaccine increases neutralizing antibodies against variants of concern in solid organ transplant recipients

Karaba, A. H., Zhu, X., Liang, T., Wang, K. H., Rittenhouse, AG., Akinde, O., Eby, Y., Ruff, J. E., Blankson, JN., Abedon, A. T., Alejo, J. L., Cox, A. L., Bailey, JR., Thompson, E. A., Klein, S. L., Warren, D. S., Garonzik-Wang, J. M., Boyarsky, B. J., Sitaras, I., Pekosz, A., & 3 othersSegev, D. L., Tobian, A. A. R. & Werbel, W. A., Apr 2022, In: American Journal of Transplantation. 22, 4, p. 1253-1260 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Persistent CAD activity in memory CD8⁺ T cells supports rRNA synthesis and ribosomal biogenesis required at rechallenge

Claiborne, M. D., Sengupta, S., Zhao, L., Arwood, M. L., Sun, I. M., Wen, J., Thompson, E. A., Mitchell-Flack, M., Laiho, M. & Powell, J. D., May 2022, In: Science Immunology. 7, 71, eabh4271.

Research output: Contribution to journal › Article › peer-review

Open Access

Sulforaphane exhibits antiviral activity against pandemic SARS-CoV-2 and seasonal HCoV-OC43 coronaviruses in vitro and in mice

Ordonez, A. A., Bullen, C. K., Villabona-Rueda, A. F., Thompson, E. A., Turner, M. L., Merino, V. F., Yan, Y., Kim, J., Davis, S. L., Komm, O., Powell, J. D., D’Alessio, F. R., Yolken, R. H., Jain, S. K. & Jones-Brando, L., Dec 2022, In: Communications biology. 5, 1, 242.

Research output: Contribution to journal › Article › peer-review

Open Access

2021

Functional characterization of CD4⁺ T cell receptors crossreactive for SARS-CoV-2 and endemic coronaviruses

Dykema, A. G., Zhang, B., Woldemeskel, B. A., Garliss, C. C., Cheung, L. S., Choudhury, D., Zhang, J., Aparicio, L., Bom, S., Rashid, R., Caushi, J. X., Hsiue, E. H. C., Cascino, K., Thompson, E. A., Kwaa, A. K., Singh, D., Thapa, S., Ordonez, A. A., Pekosz, A., D’Alessio, F. R., & 8 othersPowell, J. D., Yegnasubramanian, S., Zhou, S., Pardoll, D. M., Ji, H., Cox, A. L., Blankson, J. N. & Smith, K. N., May 2021, In: Journal of Clinical Investigation. 131, 10, e146922.

Research output: Contribution to journal › Article › peer-review

Open Access

Inhibition of the Adenosine Pathway to Potentiate Cancer Immunotherapy: Potential for Combinatorial Approaches

Thompson, E. A. & Powell, J. D., Jan 27 2021, In: Annual review of medicine. 72, p. 331-348 18 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

3 Scopus citations

Metabolic programs define dysfunctional immune responses in severe COVID-19 patients

Thompson, E. A., Cascino, K., Ordonez Suarez, A., Zhou, W., Vaghasia, A., Hamacher-Brady, A., Brady, N. R., Sun, I. H., Wang, R., Rosenberg, A. Z., Delannoy, M., Rothman, R., Fenstermacher, K., Sauer, L., Shaw Saliba, K., Bloch, E. M., Redd, A., Tobian, A. A. R., Horton, M., Smith, K., & 6 othersPekosz, A., D'Alessio, F. R., Yegnasubramanian, S., Ji, H., Cox, A. L. & Powell, J., Mar 16 2021, In: Cell Reports. 34, 11, 108863.

Research output: Contribution to journal › Article › peer-review

Open Access

2020

A motogenic gabaergic system of mononuclear phagocytes facilitates dissemination of coccidian parasites

Bhandage, A. K., Olivera, G. C., Kanatani, S., Thompson, E., Loré, K., Varas-Godoy, M. & Barragan, A., Oct 2020, In: eLife. 9, p. 1-26 26 p., e60528.

Research output: Contribution to journal › Article › peer-review

Open Access

An exploratory study of metformin with or without rapamycin as maintenance therapy after induction chemotherapy in patients with metastatic pancreatic adenocarcinoma

Bever, K. M., Borazanci, E. H., Thompson, E. A., Durham, J. N., Pinero, K., Jameson, G. S., Vrana, A., Liu, M., Wilt, C., Wu, A. A., Fu, W., Wang, H., Yin, Y., Leal, J. P., de Jesus-Acosta, A., Zheng, L., Laheru, D. A., von Hoff, D. D., Jaffee, E. M., Powell, J. D., & 1 othersLe, D. T., May 26 2020, In: Oncotarget. 11, 21, p. 1929-1941 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Route of Vaccine Administration Alters Antigen Trafficking but Not Innate or Adaptive Immunity

Ols, S., Yang, L., Thompson, E. A., Pushparaj, P., Tran, K., Liang, F., Lin, A., Eriksson, B., Karlsson Hedestam, G. B., Wyatt, R. T. & Loré, K., Mar 24 2020, In: Cell Reports. 30, 12, p. 3964-3971.e7

Research output: Contribution to journal › Article › peer-review

Open Access

2019

Comparative analysis of the germinal center response by flow cytometry and immunohistology

Lindgren, G., Ols, S., Thompson, E. A. & Loré, K., Sep 2019, In: Journal of Immunological Methods. 472, p. 16-24 9 p.

Research output: Contribution to journal › Article › peer-review

Corrigendum: Induction of robust B cell responses after influenza mRNA vaccination is accompanied by circulating hemagglutinin-specific ICOS+ PD-1+ CXCR3+ T follicular helper cells (Frontiers in Immunology (2017) 8 (1539) DOI:10.3389/fimmu.2017.01539)

Lindgren, G., Ols, S., Liang, F., Thompson, E. A., Lin, A., Hellgren, F., Bahl, K., John, S., Yuzhakov, O., Hassett, K. J., Brito, L. A., Salter, H., Ciaramella, G. & Loré, K., 2019, In: Frontiers in immunology. 10, APR, 614.

Research output: Contribution to journal › Comment/debate › peer-review

Open Access

Monocytes Acquire the Ability to Prime Tissue-Resident T Cells via IL-10-Mediated TGF-β Release

Thompson, E. A., Darrah, P. A., Foulds, K. E., Hoffer, E., Caffrey-Carr, A., Norenstedt, S., Perbeck, L., Seder, R. A., Kedl, R. M. & Loré, K., Jul 30 2019, In: Cell Reports. 28, 5, p. 1127-1135.e4

Research output: Contribution to journal › Article › peer-review

Open Access

The viral protein corona directs viral pathogenesis and amyloid aggregation

Ezzat, K., Pernemalm, M., Pålsson, S., Roberts, T. C., Järver, P., Dondalska, A., Bestas, B., Sobkowiak, M. J., Levänen, B., Sköld, M., Thompson, E. A., Saher, O., Kari, O. K., Lajunen, T., Sverremark Ekström, E., Nilsson, C., Ishchenko, Y., Malm, T., Wood, M. J. A., Power, U. F., & 6 othersMasich, S., Lindén, A., Sandberg, J. K., Lehtiö, J., Spetz, A. L. & EL Andaloussi, S., Dec 1 2019, In: Nature communications. 10, 1, 2331.

Research output: Contribution to journal › Article › peer-review

Open Access

2018

Rhesus macaque myeloid-derived suppressor cells demonstrate t cell inhibitory functions and are transiently increased after vaccination

Lin, A., Liang, F., Thompson, E. A., Vono, M., Ols, S., Lindgren, G., Hassett, K., Salter, H., Ciaramella, G. & Loré, K., Jan 1 2018, In: Journal of Immunology. 200, 1, p. 286-294 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

TLR-adjuvanted nanoparticle vaccines differentially influence the quality and longevity of responses to malaria antigen Pfs25

Thompson, E. A., Ols, S., Miura, K., Rausch, K., Narum, D. L., Spångberg, M., Juraska, M., Wille-Reece, U., Weiner, A., Howard, R. F., Long, C. A., Duffy, P. E., Johnston, L., O'Neil, C. P. & Loré, K., May 17 2018, In: JCI Insight. 3, 10

Research output: Contribution to journal › Article › peer-review

Open Access

2017

Efficient Targeting and Activation of Antigen-Presenting Cells In Vivo after Modified mRNA Vaccine Administration in Rhesus Macaques

Liang, F., Lindgren, G., Lin, A., Thompson, E. A., Ols, S., Röhss, J., John, S., Hassett, K., Yuzhakov, O., Bahl, K., Brito, L. A., Salter, H., Ciaramella, G. & Loré, K., Dec 6 2017, In: Molecular Therapy. 25, 12, p. 2635-2647 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Induction of Robust B cell responses after influenza mRNA vaccination is accompanied by circulating hemagglutinin-specific ICOS+ PD-1+ CXCR3+ T follicular helper cells

Lindgren, G., Ols, S., Liang, F., Thompson, E. A., Lin, A., Hellgren, F., Bahl, K., John, S., Yuzhakov, O., Hassett, K. J., Brito, L. A., Salter, H., Ciaramella, G. & Loré, K., Nov 13 2017, In: Frontiers in immunology. 8, NOV, 1539.

Research output: Contribution to journal › Article › peer-review

Open Access

Non-human primates as a model for understanding the mechanism of action of toll-like receptor-based vaccine adjuvants

Thompson, E. A. & Loré, K., Aug 2017, In: Current Opinion in Immunology. 47, p. 1-7 7 p.

Research output: Contribution to journal › Review article › peer-review

Vaccine priming is restricted to draining lymph nodes & controlled by adjuvant-mediated antigen uptake

Liang, F., Lindgren, G., Sandgren, K. J., Thompson, E. A., Francica, J. R., Seubert, A., Gregorio, E. D., Barnett, S., O'hagan, D. T., Sullivan, N. J., Koup, R. A., Seder, R. A. & Loré, K., Jun 7 2017, In: Science translational medicine. 9, 393, eaal2094.

Research output: Contribution to journal › Article › peer-review

2015

Design and evaluation of surface and adjuvant modified PLGA microspheres for uptake by dendritic cells to improve vaccine responses

Salvador, A., Sandgren, K. J., Liang, F., Thompson, E. A., Koup, R. A., Pedraz, J. L., Hernandez, R. M., Loré, K. & Igartua, M., Dec 30 2015, In: International Journal of Pharmaceutics. 496, 2, p. 371-381 11 p.

Research output: Contribution to journal › Article › peer-review

Human anti-CD40 antibody and poly IC:LC adjuvant combination induces potent T cell responses in the lung of nonhuman primates

Thompson, E. A., Liang, F., Lindgren, G., Sandgren, K. J., Quinn, K. M., Darrah, P. A., Koup, R. A., Seder, R. A., Kedl, R. M. & Loré, K., Aug 1 2015, In: Journal of Immunology. 195, 3, p. 1015-1024 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2014

Tissue myeloid cells in SIV-infected primates acquire viral DNA through phagocytosis of infected T cells

Calantone, N., Wu, F., Klase, Z., Deleage, C., Perkins, M., Matsuda, K., Thompson, E. A., Ortiz, A. M., Vinton, C. L., Ourmanov, I., Loré, K., Douek, D. C., Estes, J. D., Hirsch, V. M. & Brenchley, J. M., Sep 18 2014, In: Immunity. 41, 3, p. 493-502 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2012

Activated iNKT cells promote memory CD8⁺ T cell differentiation during viral infection

Reilly, E. C., Thompson, E. A., Aspeslagh, S., Wands, J. R., Elewaut, D. & Brossay, L., May 23 2012, In: PloS one. 7, 5, e37991.

Research output: Contribution to journal › Article › peer-review

Open Access

Elizabeth Thompson

Research output

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