Edward Chen

Research output

Research output per year 2001 2005 2017 2018 2020 2021 2022 2023 2023

• 42 Article
• 12 Review article
• 4 Chapter
• 2 Editorial
• 2 More
  • 1 Comment/debate
  • 1 Letter

Research output per year

Research output per year

Search results

• 2023

  Activity tracking devices in sarcoidosis

  FSR Clinical Studies Network, Mar 2023, In: Sarcoidosis Vasculitis and Diffuse Lung Diseases. 40, 1, e2023010.

  Research output: Contribution to journal › Article › peer-review

  • Sarcoidosis 100%
  • Fitness Trackers 57%
  • Equipment and Supplies 54%
  • African Americans 10%
  • Technology 7%

• Heterogeneity of Lung Function Phenotypes in Sarcoidosis: Role of Race and Sex Differences

  Sharp, M., Psoter, K. J., Balasubramanian, A., Pulapaka, A. V., Chen, E. S., Brown, S. A. W., Mathai, S. C., Gilotra, N. A., Chrispin, J., Bascom, R., Bernstein, R., Eakin, M. N., Wise, R. A., Moller, D. R. & McCormack, M. C., Jan 1 2023, In: Annals of the American Thoracic Society. 20, 1, p. 30-37 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Sarcoidosis 100%
  • Sex Characteristics 85%
  • Phenotype 55%
  • Lung 49%
  • Respiratory Function Tests 20%

• Sex and Race Differences in Cardiac Sarcoidosis Presentation, Treatment and Outcomes

  DUVALL, CHLOE., PAVLOVIC, NOELLE., ROSEN, NATALIE. S., WAND, ALISON. L., GRIFFIN, JAN. M., OKADA, DAVID. R., TANDRI, HARIKRISHNA., KASPER, EDWARD. K., SHARP, MICHELLE., CHEN, EDWARD. S., CHRISPIN, JONATHAN. & GILOTRA, NISHA. A., Aug 2023, In: Journal of cardiac failure. 29, 8, p. 1135-1145 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Sarcoidosis 100%
  • Sex Characteristics 85%
  • Cardiac Arrhythmias 22%
  • Cause of Death 20%
  • Steroids 19%

• Standardization of flow cytometry and cell sorting to enable a transcriptomic analysis in a multi-site sarcoidosis study

  Magallon, R. E., Harmacek, L. D., Arger, N. K., Grewal, P., Powers, L., Werner, B. R., Barkes, B. Q., Li, L., MacPhail, K., Gillespie, M., White, E. K., Collins, S. E., Brown, T., Cardenas, J., Chen, E. S., Maier, L. A., Leach, S. M., Hamzeh, N. Y., Koth, L. L. & O'Connor, B. P., 2023, In: PloS one. 18, 3, p. e0281210

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Sarcoidosis 100%
  • Flow Cytometry 70%
  • T-Lymphocytes 45%
  • RNA Sequence Analysis 41%
  • Cell Lineage 38%
• 2022

  Autoantibody profile in sarcoidosis, analysis from the GRADS sarcoidosis cohort

  GRADS investigators, Oct 2022, In: PloS one. 17, 10 October, e0274381.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Sarcoidosis 100%
  • Trypsin 93%
  • Autoantibodies 84%
  • Immunoglobulin M 37%
  • Immunoglobulin G 18%

• Cardiac sarcoidosis outcome differences: A comparison of patients with de novo cardiac versus known extracardiac sarcoidosis at presentation

  Rosen, N. S., Pavlovic, N., Duvall, C., Wand, A. L., Griffin, J. M., Okada, D. R., Chrispin, J., Tandri, H., Mathai, S. C., Stern, B., Pardo, C. A., Kasper, E. K., Sharp, M., Chen, E. S. & Gilotra, N. A., Jul 2022, In: Respiratory Medicine. 198, 106864.

  Research output: Contribution to journal › Article › peer-review

  • Sarcoidosis 100%
  • Cardiac Arrhythmias 15%
  • Heart Transplantation 12%
  • Heart Block 7%
  • Heart-Assist Devices 7%

• Effect of Corticosteroids on Left Ventricular Function in Patients With Cardiac Sarcoidosis

  Wand, A. L., Pavlovic, N., Duvall, C., Rosen, N. S., Chasler, J., Griffin, J. M., Okada, D. R., Jefferson, A., Chrispin, J., Tandri, H., Mathai, S. C., Sharp, M., Chen, E. S., Kasper, E. K., Hays, A. G. & Gilotra, N. A., Aug 15 2022, In: American Journal of Cardiology. 177, p. 108-115 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Sarcoidosis 100%
  • Left Ventricular Function 89%
  • Stroke Volume 83%
  • Adrenal Cortex Hormones 74%
  • Odds Ratio 10%

• Factors driving provider adoption of the TREWS machine learning-based early warning system and its effects on sepsis treatment timing

  Henry, K. E., Adams, R., Parent, C., Soleimani, H., Sridharan, A., Johnson, L., Hager, D. N., Cosgrove, S. E., Markowski, A., Klein, E. Y., Chen, E. S., Saheed, M. O., Henley, M., Miranda, S., Houston, K., Linton, R. C., Ahluwalia, A. R., Wu, A. W. & Saria, S., Jul 2022, In: Nature medicine. 28, 7, p. 1447-1454 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Machine Learning 100%
  • Sepsis 71%
  • Time 31%
  • Antimicrobial Agent 30%
  • Reduction 20%

• Prospective, multi-site study of patient outcomes after implementation of the TREWS machine learning-based early warning system for sepsis

  Adams, R., Henry, K. E., Sridharan, A., Soleimani, H., Zhan, A., Rawat, N., Johnson, L., Hager, D. N., Cosgrove, S. E., Markowski, A., Klein, E. Y., Chen, E. S., Saheed, M. O., Henley, M., Miranda, S., Houston, K., Linton, R. C., Ahluwalia, A. R., Wu, A. W. & Saria, S., Jul 2022, In: Nature medicine. 28, 7, p. 1455-1460 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Machine Learning 100%
  • Sepsis 71%
  • Health Care Outcome Assessment 58%
  • Reduction 40%
  • Time 21%

• Risk Factors for Infection and Health Impacts of the Coronavirus Disease 2019 (COVID-19) Pandemic in People With Autoimmune Diseases

  Fitzgerald, K. C., Mecoli, C. A., Douglas, M., Harris, S., Aravidis, B., Albayda, J., Sotirchos, E. S., Hoke, A., Orbai, A. M., Petri, M., Christopher-Stine, L., Baer, A. N., Paik, J. J., Adler, B. L., Tiniakou, E., Timlin, H., Bhargava, P., Newsome, S. D., Venkatesan, A., Chaudhry, V., & 14 othersLloyd, T., Pardo, C. A., Stern, B. J., Lazarev, M., Truta, B., Saidha, S., Chen, E. S., Sharp, M., Gilotra, N., Kasper, E. K., Gelber, A. C., Bingham, C. O., Shah, A. A. & Mowry, E. M., Feb 1 2022, In: Clinical Infectious Diseases. 74, 3, p. 427-436 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Coronavirus 100%
  • Pandemics 84%
  • Autoimmune Diseases 68%
  • Health 38%
  • Infections 37%

• The association of baseline sarcoidosis measurements with 6-month outcomes that are of interest to patients: Results from the On-line Sarcoidosis Assessment Platform Study (OSAP)

  Judson, M. A., Yucel, R., Preston, S., Chen, E. S., Culver, D. A., Hamzeh, N., Lower, E. E., Sweiss, N. J., Valeyre, D., Veltkamp, M., Victorson, D. E., Beaumont, J. L., Singh, N., Shivas, T., Vancavage, R. & Baughman, R. P., May 2022, In: Respiratory Medicine. 196, 106819.

  Research output: Contribution to journal › Article › peer-review

  • Sarcoidosis 100%
  • Quality of Life 14%
  • Patient Acceptance of Health Care 6%
  • Global Health 5%
  • Health Status 4%
• 2021

  Clinical and Imaging Response to Tumor Necrosis Factor Alpha Inhibitors in Treatment of Cardiac Sarcoidosis: A Multicenter Experience

  Gilotra, N. A., Wand, A. L., Pillarisetty, A., Devraj, M., Pavlovic, N., Ahmed, S., Saad, E., Solnes, L., Garcia, C., Okada, D. R., Constantinescu, F., Mohammed, S. F., Griffin, J. M., Kasper, E. K., Chen, E. S. & Sheikh, F. H., Jan 2021, In: Journal of cardiac failure. 27, 1, p. 83-91 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Tumor Necrosis Factor Inhibitors 100%
  • Sarcoidosis 89%
  • Tumor Necrosis Factor-alpha 58%
  • tumor necrosis factor precursor 22%
  • Infections 19%

• Comparing Critical Care Admissions among Urban Populations before and during the COVID-19 Pandemic

  Galiatsatos, P., Page, K. R., Chatterjee, S., Maygers, J., Sarker, S., Jones, V., Lugo, A., Tolson, T., Hill-Briggs, F., Chen, E. S. & Golden, S. H., Jun 1 2021, In: Health Security. 19, S1, p. S34-S40

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • pandemics 100%
  • Intensive care units 99%
  • Urban Population 91%
  • urban population 85%
  • Pandemics 79%

• Defining CD4 T helper and T regulatory cell endotypes of progressive and remitting pulmonary sarcoidosis (BRITE): Protocol for a US-based, multicentre, longitudinal observational bronchoscopy study

  Koth, L. L., Harmacek, L. D., White, E. K., Arger, N. K., Powers, L., Werner, B. R., Magallon, R. E., Grewal, P., Barkes, B. Q., Li, L., Gillespie, M., Collins, S. E., Cardenas, J., Chen, E. S., Maier, L. A., Leach, S. M., O'Connor, B. P. & Hamzeh, N. Y., Nov 9 2021, In: BMJ open. 11, 11, e056841.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Pulmonary Sarcoidosis 100%
  • Sarcoidosis 77%
  • Bronchoscopy 76%
  • Helper-Inducer T-Lymphocytes 73%
  • Research Ethics Committees 62%

• Evaluating the Minimal Clinically Important Difference of the King’s Sarcoidosis Questionnaire in a Multicenter Prospective Study

  Baughman, R. P., Judson, M. A., Beaumont, J. L., Maier, L. A., Sweiss, N. J., Culver, D. A., Chen, E. S., Singh, N., Lower, E. E., Reeves, R., Hamzeh, N., Grutters, J. C., Valeyre, D. & Birring, S. S., Mar 2021, In: Annals of the American Thoracic Society. 18, 3, p. 477-485 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Minimal Clinically Important Difference 100%
  • Sarcoidosis 73%
  • Multicenter Studies 58%
  • Prospective Studies 43%
  • Lung 10%
  1 Scopus citations

• Gene coexpression networks reveal novel molecular endotypes in alpha-1 antitrypsin deficiency

  Chu, J. H., Zang, W., Vukmirovic, M., Yan, X., Adams, T., Deiuliis, G., Hu, B., Mihaljinec, A., Schupp, J. C., Becich, M. J., Hochheiser, H., Gibson, K. F., Chen, E. S., Morris, A., Leader, J. K., Wisniewski, S. R., Zhang, Y., Sciurba, F. C., Collman, R. G., Sandhaus, R., & 5 othersHerzog, E. L., Patterson, K. C., Sauler, M., Strange, C. & Kaminski, N., Feb 1 2021, In: Thorax. 76, 2, p. 134-143 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • alpha 1-Antitrypsin Deficiency 100%
  • Gene Regulatory Networks 74%
  • Gene Expression 28%
  • Bronchoalveolar Lavage 22%
  • Blood Cells 16%

• Implementation of a Protocol Using the 5-Item Brief Alcohol Withdrawal Scale for Treatment of Severe Alcohol Withdrawal in Intensive Care Units

  Rastegar, D. A., Jarrell, A. S. & Chen, E. S., Oct 2021, In: Journal of Intensive Care Medicine. 36, 11, p. 1361-1365 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Intensive Care Units 100%
  • Alcohols 90%
  • Benzodiazepines 82%
  • Length of Stay 30%
  • Phenobarbital 22%
  1 Scopus citations

• Management of Cardiac Sarcoidosis Using Mycophenolate Mofetil as a Steroid-Sparing Agent

  Griffin, J. M., Chasler, J., Wand, A. L., Okada, D. R., Smith, J. N., Saad, E., Tandri, H., Chrispin, J., Sharp, M., Kasper, E. K., Chen, E. S. & Gilotra, N. A., Dec 2021, In: Journal of cardiac failure. 27, 12, p. 1348-1358 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Mycophenolic Acid 100%
  • Sarcoidosis 93%
  • Prednisone 87%
  • Steroids 63%
  • Fluorodeoxyglucose F18 29%

• Transcriptomics of bronchoalveolar lavage cells identifies new molecular endotypes of sarcoidosis

  Vukmirovic, M., Yan, X., Gibson, K. F., Gulati, M., Schupp, J. C., DeIuliis, G., Adams, T. S., Hu, B., Mihaljinec, A., Woolard, T. N., Lynn, H., Emeagwali, N., Herzog, E. L., Chen, E. S., Morris, A., Leader, J. K., Zhang, Y., Garcia, J. G. N., Maier, L. A., Collman, R. G., & 9 othersDrake, W. P., Becich, M. J., Hochheiser, H., Wisniewski, S. R., Benos, P. V., Moller, D. R., Prasse, A., Koth, L. L. & Kaminski, N., Dec 1 2021, In: European Respiratory Journal. 58, 6

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Sarcoidosis 100%
  • Bronchoalveolar Lavage 99%
  • Pulmonary Sarcoidosis 51%
  • Gene Expression 44%
  • Lymphadenopathy 37%
• 2020

  Association of Medication Adherence and Clinical Outcomes in Sarcoidosis

  Sharp, M., Brown, T., Chen, E. S., Rand, C. S., Moller, D. R. & Eakin, M. N., Jul 2020, In: CHEST. 158, 1, p. 226-233 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Medication Adherence 100%
  • Sarcoidosis 98%
  • Patient Acceptance of Health Care 26%
  • African Continental Ancestry Group 22%
  • Quality of Life 21%
  1 Scopus citations

• Clinical and MRI phenotypes of sarcoidosis-associated myelopathy

  Murphy, O. C., Salazar-Camelo, A., Jimenez, J. A., Barreras, P., Reyes, M. I., Garcia, M. A., Moller, D. R., Chen, E. S. & Pardo, C. A., Jul 8 2020, In: Neurology: Neuroimmunology and NeuroInflammation. 7, 4, e722.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Spinal Cord Diseases 100%
  • Sarcoidosis 95%
  • Myelitis 61%
  • Phenotype 52%
  • Neurosarcoidosis 22%
  6 Scopus citations

• The Association Between Neighborhood Socioeconomic Disadvantage and Readmissions for Patients Hospitalized With Sepsis

  Galiatsatos, P., Follin, A., Alghanim, F., Sherry, M., Sylvester, C., Daniel, Y., Chanmugam, A., Townsend, J., Saria, S., Kind, A. J. & Chen, E., Jun 1 2020, In: Critical care medicine. 48, 6, p. 808-814 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Patient Readmission 100%
  • Sepsis 69%
  • Logistic Models 25%
  • Vulnerable Populations 20%
  • International Classification of Diseases 19%
  2 Scopus citations
• 2019

  Evaluation of the Brief Alcohol Withdrawal Scale Protocol at an Academic Medical Center

  Lindner, B. K., Gilmore, V. T., Kruer, R. M., Alvanzo, A. A. H., Chen, E. S., Murray, P., Niessen, T., Perrin, K., Rastegar, D. A., Young, S. & Jarrell, A. S., Sep 1 2019, In: Journal of addiction medicine. 13, 5, p. 379-384 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Alcohols 100%
  • Benzodiazepines 68%
  • Delirium 45%
  • Lorazepam 35%
  • Substance Withdrawal Syndrome 16%
  3 Scopus citations

• Psychological burden associated with worse clinical outcomes in sarcoidosis

  Sharp, M., Brown, T., Chen, E., Rand, C. S., Moller, D. R. & Eakin, M. N., Sep 1 2019, In: BMJ Open Respiratory Research. 6, 1, e000467.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Sarcoidosis 100%
  • Psychology 62%
  • Anxiety 47%
  • Pulmonary Sarcoidosis 36%
  • Quality of Life 25%
  1 Scopus citations
• 2018

  A Contemporary Analysis of Heart Transplantation and Bridge-to-Transplant Mechanical Circulatory Support Outcomes in Cardiac Sarcoidosis

  Crawford, T. C., Okada, D. R., Magruder, J. T., Fraser, C., Patel, N., Houston, B. A., Whitman, G. J., Mandal, K., Zehr, K. J., Higgins, R. S., Chen, E. S., Tandri, H., Kasper, E. K., Tedford, R. J., Russell, S. D. & Gilotra, N. A., Jun 2018, In: Journal of cardiac failure. 24, 6, p. 384-391 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Sarcoidosis 100%
  • Heart Transplantation 97%
  • Transplants 57%
  • Survival 6%
  • Mortality 6%
  12 Scopus citations

• The effect of community socioeconomic status on sepsis-attributable mortality

  Galiatsatos, P., Brigham, E. P., Pietri, J., Littleton, K., Hwang, S., Grant, M. C., Hansel, N. N. & Chen, E. S., Aug 2018, In: Journal of Critical Care. 46, p. 129-133 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Social Class 100%
  • Sepsis 85%
  • Mortality 53%
  • Income 51%
  • Poverty 22%
  7 Scopus citations
• 2017

  Development and implementation of an alcohol withdrawal protocol using a 5-item scale, the Brief Alcohol Withdrawal Scale (BAWS)

  Rastegar, D. A., Applewhite, D., Alvanzo, A. A. H., Welsh, C., Niessen, T. & Chen, E. S., Oct 2 2017, In: Substance Abuse. 38, 4, p. 394-400 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Alcohols 100%
  • Substance Withdrawal Syndrome 61%
  • Methadone 19%
  • Delirium 19%
  • Diazepam 18%
  4 Scopus citations

• Genetic, immunologic, and environmental basis of sarcoidosis

  Moller, D. R., Rybicki, B. A., Hamzeh, N. Y., Montgomery, C. G., Chen, E. S., Drake, W. & Fontenot, A. P., Dec 2017, In: Annals of the American Thoracic Society. 14, p. S429-S436

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Sarcoidosis 100%
  • National Heart, Lung, and Blood Institute (U.S.) 41%
  • Phenotype 36%
  • Environmental Exposure 33%
  • Immunologic Factors 33%
  29 Scopus citations

• Joint SNMMI–ASNC expert consensus document on the role of ¹⁸F-FDG PET/CT in cardiac sarcoid detection and therapy monitoring

  Chareonthaitawee, P., Beanlands, R. S., Chen, W., Dorbala, S., Miller, E. J., Murthy, V. L., Birnie, D. H., Chen, E. S., Cooper, L. T., Tung, R. H., White, E. S., Borges-Neto, S., Di Carli, M. F., Gropler, R. J., Ruddy, T. D., Schindler, T. H. & Blankstein, R., Oct 1 2017, In: Journal of Nuclear Cardiology. 24, 5, p. 1741-1758 18 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  57 Scopus citations

• Joint SNMMI-ASNC expert consensus document on the role of ¹⁸F-FDG PET/CT in carDiac sarcoid detection and therapy monitoring writing group

  Chareonthaitawee, P., Beanlands, R. S., Chen, W., Dorbala, S., Miller, E. J., Murthy, V. L., Birnie, D. H., Chen, E. S., Cooper, L. T., Tung, R. H., White, E. S., Borges-Neto, S., Di Carli, M. F., Gropler, R. J., Ruddy, T. D., Schindler, T. H., Blankstein, R., Bateman, T. M., Cerqueira, M. D., Dilsizian, V., & 5 othersHeller, G. V., Moller, D. R., Osborne, M. T., Sadeghi, M. M. & Soman, P., Aug 1 2017, In: Journal of Nuclear Medicine. 58, 8, p. 1341-1353 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  76 Scopus citations

• Myocardial Blood Flow and Inflammatory Cardiac Sarcoidosis

  Kruse, M. J., Kovell, L., Kasper, E. K., Pomper, M. G., Moller, D. R., Solnes, L., Chen, E. S. & Schindler, T. H., Feb 1 2017, In: JACC: Cardiovascular Imaging. 10, 2, p. 157-167 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Sarcoidosis 100%
  • Inflammation 54%
  • Perfusion 26%
  • Positron-Emission Tomography 21%
  • regadenoson 20%
  21 Scopus citations
• 2014

  Etiologic role of infectious agents

  Chen, E. S. & Moller, D. R., Jun 2014, In: Seminars in Respiratory and Critical Care Medicine. 35, 3, p. 285-295 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Sarcoidosis 100%
  • Propionibacterium 12%
  • Serum Amyloid A Protein 11%
  • Histocompatibility Antigens Class II 9%
  • Mycobacterium 9%
  19 Scopus citations
• 2013

  Diagnosis of Amyloidosis and Differentiation from Chronic, Idiopathic Enterocolitis in Rhesus (Macaca mulatta) and Pig-Tailed (M. nemestrina) Macaques

  Rice, K. A., Chen, E. S., Pate, K. A. M., Hutchinson, E. K. & Adams, R. J., Jun 2013, In: Comparative medicine. 63, 3, p. 262-271 10 p.

  Research output: Contribution to journal › Article › peer-review

  • enterocolitis 100%
  • amyloidosis 95%
  • Macaca nemestrina 95%
  • Enterocolitis 91%
  • amyloid 78%
  9 Scopus citations
• 2012

  Antigen-specific multifunctional T-cells in sarcoidosis patients with Löfgren's syndrome

  Wikén, M., Ostadkarampour, M., Eklund, A., Willett, M., Chen, E., Moller, D., Grunewald, J. & Wahlström, J., Jul 1 2012, In: European Respiratory Journal. 40, 1, p. 110-121 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Sarcoidosis 100%
  • Interferons 60%
  • Antigens 58%
  • T-Lymphocytes 56%
  • Bronchoalveolar Lavage Fluid 56%
  14 Scopus citations

• Peripheral Blood Gene Expression as a Novel Genomic Biomarker in Complicated Sarcoidosis

  Zhou, T., Zhang, W., Sweiss, N. J., Chen, E. S., Moller, D. R., Knox, K. S., Ma, S. F., Wade, M. S., Noth, I., Machado, R. F. & Garcia, J. G. N., Sep 12 2012, In: PloS one. 7, 9, e44818.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Sarcoidosis 100%
  • biomarkers 83%
  • Biological Marker 82%
  • Biomarkers 59%
  • genomics 58%
  52 Scopus citations
• 2010

  Serum amyloid a regulates granulomatous inflammation in sarcoidosis through toll-like receptor-2

  Chen, E. S., Song, Z., Willett, M. H., Heine, S., Yung, R. C., Liu, M. C., Groshong, S. D., Zhang, Y., Tuder, R. M. & Moller, D. R., Feb 15 2010, In: American journal of respiratory and critical care medicine. 181, 4, p. 360-373 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Toll-Like Receptor 2 100%
  • Sarcoidosis 85%
  • Amyloid 74%
  • Serum Amyloid A Protein 66%
  • Inflammation 46%
  145 Scopus citations
• 2008

  T cell responses to mycobacterial catalase-peroxidase profile a pathogenic antigen in systemic sarcoidosis

  Chen, E. S., Wahlström, J., Song, Z., Willett, M. H., Wikén, M., Yung, R. C., West, E. E., McDyer, J. F., Zhang, Y., Eklund, A., Grunewald, J. & Moller, D. R., Dec 15 2008, In: Journal of Immunology. 181, 12, p. 8784-8796 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Sarcoidosis 100%
  • Peroxidase 88%
  • Catalase 88%
  • Antigens 58%
  • T-Lymphocytes 56%
  119 Scopus citations
• 2006

  Pluripotent allospecific CD8⁺ effector T cells traffic to lung in murine obliterative airway disease

  West, E. E., Lavoie, T. L., Orens, J. B., Chen, E. S., Ye, S. Q., Finkelman, F. D., Garcia, J. G. N. & McDyer, J. F., Jan 2006, In: American journal of respiratory cell and molecular biology. 34, 1, p. 108-118 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Effector 100%
  • T-Lymphocytes 56%
  • Lung 49%
  • Allografts 40%
  • Isografts 16%
  23 Scopus citations
• 2005

  ACAT1 deletion in murine macrophages associated with cytotoxicity and decreased expression of collagen type 3A1

  Rodriguez, A., Ashen, M. D. & Chen, E. S., May 27 2005, In: Biochemical and Biophysical Research Communications. 331, 1, p. 61-68 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Collagen 100%
  • Cholesterol 94%
  • Macrophages 73%
  • Foam 71%
  • Foam Cells 44%
  1 Scopus citations

• Mycobacterial catalase-peroxidase is a tissue antigen and target of the adaptive immune response in systemic sarcoidosis

  Song, Z., Marzilli, L., Greenlee, B. M., Chen, E. S., Silver, R. F., Askin, F. B., Teirstein, A. S., Zhang, Y., Cotter, R. J. & Moller, D. R., Mar 7 2005, In: Journal of Experimental Medicine. 201, 5, p. 755-767 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Sarcoidosis 100%
  • Adaptive Immunity 93%
  • Peroxidase 88%
  • Catalase 88%
  • Antigens 58%
  259 Scopus citations
• 2001

  Attenuation of lung inflammation and fibrosis in interferon-γ-deficient mice after intratracheal bleomycin

  Chen, E. S., Greenlee, B. M., Wills-Karp, M. & Moller, D. R., 2001, In: American journal of respiratory cell and molecular biology. 24, 5, p. 545-555 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Intratracheal 100%
  • Bleomycin 82%
  • Interferons 56%
  • Pneumonia 49%
  • Fibrosis 45%
  105 Scopus citations

• Bleomycin-induced pulmonary fibrosis is attenuated in interferon-γ knockout mice

  Chen, E. S., Greenlee, B. M., Wills-Karp, M. & Moller, D. R., 2001, In: CHEST. 120, SUPPL., p. 8S

  Research output: Contribution to journal › Article › peer-review
  1 Scopus citations