Research output per year
Research output per year
- 1 - 50 out of 62 results
Search results
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2023
Concomitant analyses of intratumoral microbiota and genomic features reveal distinct racial differences in breast cancer
Parida, S., Siddharth, S., Xia, Y. & Sharma, D., Dec 2023, In: npj Breast Cancer. 9, 1, 4.Research output: Contribution to journal › Article › peer-review
Open Access -
Gut colonization with an obesity-associated enteropathogenic microbe modulates the premetastatic niches to promote breast cancer lung and liver metastasis
Parida, S., Siddharth, S., Gatla, H. R., Wu, S., Wang, G., Gabrielson, K., Sears, C. L., Ladle, B. H. & Sharma, D., 2023, In: Frontiers in immunology. 14, 1194931.Research output: Contribution to journal › Article › peer-review
Open Access -
Jaboticaba (Myrciaria jaboticaba) peel extracts induce reticulum stress and apoptosis in breast cancer cells
da Silva-Maia, J. K., Nagalingam, A., Cazarin, C. B. B., Marostica Junior, M. R. & Sharma, D., Jul 30 2023, In: Food Chemistry: Molecular Sciences. 6, 100167.Research output: Contribution to journal › Article › peer-review
Open Access -
2022
Label-Free Vibrational and Quantitative Phase Microscopy Reveals Remarkable Pathogen-Induced Morphomolecular Divergence in Tumor-Derived Cells
Liu, Z., Parida, S., Wu, S., Sears, C. L., Sharma, D. & Barman, I., May 27 2022, In: ACS sensors. 7, 5, p. 1495-1505 11 p.Research output: Contribution to journal › Article › peer-review
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Metformin Enhances the Anti-Cancer Efficacy of Sorafenib via Suppressing MAPK/ERK/Stat3 Axis in Hepatocellular Carcinoma
Siddharth, S., Kuppusamy, P., Wu, Q., Nagalingam, A., Saxena, N. K. & Sharma, D., Aug 2022, In: International journal of molecular sciences. 23, 15, 8083.Research output: Contribution to journal › Article › peer-review
Open Access -
Weight Gain after Hormone Receptor-Positive Breast Cancer
Goyal, A., Milner, G. E., Cimino-Mathews, A., Visvanathan, K., Wolff, A. C., Sharma, D. & Sheng, J. Y., Jun 2022, In: Current Oncology. 29, 6, p. 4090-4103 14 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2021
A procarcinogenic colon microbe promotes breast tumorigenesis and metastatic progression and concomitantly activates notch and b-catenin axes
Parida, S., Wu, S., Siddharth, S., Wang, G., Muniraj, N., Nagalingam, A., Hum, C., Mistriotis, P., Hao, H., Conover Talbot, C., Konstantopoulos, K., Gabrielson, K. L., Sears, C. L. & Sharma, D., May 2021, In: Cancer discovery. 11, 5, p. 1138-1157 20 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Concomitant activation of GLI1 and Notch1 contributes to racial disparity of human triple negative breast cancer progression
Siddharth, S., Parida, S., Muniraj, N., Hercules, S., Lim, D., Nagalingam, A., Wang, C., Gyorffy, B., Daniel, J. M. & Sharma, D., Dec 2021, In: eLife. 10, e70729.Research output: Contribution to journal › Article › peer-review
Open Access -
Hyperleptinemia in obese state renders luminal breast cancers refractory to tamoxifen by coordinating a crosstalk between Med1, miR205 and ErbB
Nagalingam, A., Siddharth, S., Parida, S., Muniraj, N., Avtanski, D., Kuppusamy, P., Elsey, J., Arbiser, J. L., Győrffy, B. & Sharma, D., Dec 2021, In: npj Breast Cancer. 7, 1, 105.Research output: Contribution to journal › Article › peer-review
Open Access -
Role of omentin in obesity paradox in lung cancer
Parida, S., Siddharth, S. & Sharma, D., Jan 2 2021, In: Cancers. 13, 2, p. 1-17 17 p., 275.Research output: Contribution to journal › Article › peer-review
Open Access -
Therapeutic targeting with DABIL-4 depletes myeloid suppressor cells in 4T1 triple-negative breast cancer model
Parveen, S., Siddharth, S., Cheung, L. S., Kumar, A., Shen, J., Murphy, J. R., Sharma, D. & Bishai, W. R., May 2021, In: Molecular oncology. 15, 5, p. 1330-1344 15 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2020
Induction of STK11-dependent cytoprotective autophagy in breast cancer cells upon honokiol treatment
Muniraj, N., Siddharth, S., Shriver, M., Nagalingam, A., Parida, S., Woo, J., Elsey, J., Gabrielson, K., Gabrielson, E., Arbiser, J. L., Saxena, N. K. & Sharma, D., Dec 1 2020, In: Cell Death Discovery. 6, 1, 81.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
The Effects of a remote-based weight loss program on adipocytokines, metabolic markers, and telomere length in breast cancer survivors: The POWER-remote trial
Santa-Maria, C. A., Coughlin, J. W., Sharma, D., Armanios, M., Blackford, A. L., Schreyer, C., Dalcin, A., Carpenter, A., Jerome, G. J., Armstrong, D. K., Chaudhry, M., Cohen, G. I., Connolly, R. M., Fetting, J., Miller, R. S., Smith, K. L., Snyder, C., Wolfe, A., Wolff, A. C., Huang, C. Y., & 2 others, Jun 15 2020, In: Clinical Cancer Research. 26, 12, p. 3024-3034 11 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
2019
Concomitant inhibition of cytoprotective autophagy augments the efficacy of Withaferin a in hepatocellular carcinoma
Siddharth, S., Muniraj, N., Saxena, N. K. & Sharma, D., Apr 2019, In: Cancers. 11, 4, 453.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
Quest for tangible biomarkers for triple-negative breast cancer
Sharma, D., Apr 15 2019, In: Cancer Research. 79, 8, p. 1746-1748 3 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Withaferin A inhibits lysosomal activity to block autophagic flux and induces apoptosis via energetic impairment in breast cancer cells
Muniraj, N., Siddharth, S., Nagalingam, A., Walker, A., Woo, J., Gyorffy, B., Gabrielson, E., Saxena, N. K. & Sharma, DI., Sep 1 2019, In: Carcinogenesis. 40, 9, p. 1110-1120 11 p.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
2018
Enhancement in the Transdermal and Localized Delivery of Honokiol Through Breast Tissue
Gao, X., Patel, M. G., Bakshi, P., Sharma, D. & Banga, A. K., Nov 1 2018, In: AAPS PharmSciTech. 19, 8, p. 3501-3511 11 p.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
Nrf2 signaling and autophagy are complementary in protecting breast cancer cells during glucose deprivation
Walker, A., Singh, A., Tully, E., Woo, J., Le, A., Nguyen, T., Biswal, S., Sharma, D. & Gabrielson, E., May 20 2018, In: Free Radical Biology and Medicine. 120, p. 407-413 7 p.Research output: Contribution to journal › Article › peer-review
21 Scopus citations -
Obese breast cancer patients and survivors: Management considerations
Sheng, J. Y., Sharma, D., Jerome, G. & Santa-Maria, C. A., 2018, In: ONCOLOGY (United States). 32, 8, p. 410-417 8 p.Research output: Contribution to journal › Article › peer-review
13 Scopus citations -
Racial disparity and triple-negative breast cancer in African-American women: A multifaceted affair between obesity, biology, and socioeconomic determinants
Siddharth, S. & Sharma, D., Dec 2018, In: Cancers. 10, 12, 514.Research output: Contribution to journal › Article › peer-review
Open Access40 Scopus citations -
2017
Activation of tumor suppressor LKB1 by honokiol abrogates cancer stem-like phenotype in breast cancer via inhibition of oncogenic Stat3
Sengupta, S., Nagalingam, A., Muniraj, N., Bonner, M. Y., Mistriotis, P., Afthinos, A., Kuppusamy, P., Lanoue, D., Cho, S., Korangath, P., Shriver, M., Begum, A., Merino, V. F., Huang, C. Y., Arbiser, J. L., Matsui, W., Györffy, B., Konstantopoulos, K., Sukumar, S., Marignani, P. A., & 2 others, Oct 12 2017, In: Oncogene. 36, 41, p. 5709-5721 13 p.Research output: Contribution to journal › Article › peer-review
Open Access47 Scopus citations -
ADIPOQ/adiponectin induces cytotoxic autophagy in breast cancer cells through STK11/LKB1-mediated activation of the AMPK-ULK1 axis
Chung, S. J., Nagaraju, G. P., Nagalingam, A., Muniraj, N., Kuppusamy, P., Walker, A., Woo, J., Győrffy, B., Gabrielson, E., Saxena, N. K. & Sharma, D., Aug 3 2017, In: Autophagy. 13, 8, p. 1386-1403 18 p.Research output: Contribution to journal › Article › peer-review
Open Access60 Scopus citations -
Benzyl Isothiocyanate potentiates p53 signaling and antitumor effects against breast cancer through activation of p53-LKB1 and p73-LKB1 axes
Xie, B., Nagalingam, A., Kuppusamy, P., Muniraj, N., Langford, P., Gyorffy, B., Saxena, N. K. & Sharma, D., Jan 10 2017, In: Scientific reports. 7, 40070.Research output: Contribution to journal › Article › peer-review
Open Access21 Scopus citations -
Concomitant activation of ETS-like transcription factor-1 and Death Receptor-5 via extracellular signal-regulated kinase in withaferin A-mediated inhibition of hepatocarcinogenesis in mice
Kuppusamy, P., Nagalingam, A., Muniraj, N., Saxena, N. K. & Sharma, D., Dec 1 2017, In: Scientific reports. 7, 1, 17943.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
Synthesis and biological evaluation of triazole-vanillin molecular hybrids as anti-cancer agents
Sharma, G. V. M., Kumar, K. S., Reddy, S. V., Nagalingam, A., Cunningham, K. M., Ummanni, R., Hugel, H., Sharma, D. & Malhotra, S. V., Sep 1 2017, In: Current Bioactive Compounds. 13, 3, p. 223-235 13 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
2016
Indolo-pyrido-isoquinolin based alkaloid inhibits growth, invasion and migration of breast cancer cells via activation of p53-miR34a axis
Avtanski, D. B., Nagalingam, A., Tomaszewski, J. E., Risbood, P., Difillippantonio, M. J., Saxena, N. K., Malhotra, S. V. & Sharma, D., Aug 1 2016, In: Molecular oncology. 10, 7, p. 1118-1132 15 p.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
In Vitro Effects of Pioglitazone on the Expression of Components of Wnt Signaling Pathway and Markers of Bone Mineralization
Avtanski, D., Hirth, Y., Babushkin, N., Sy, V., Sharma, D., Poretsky, L. & Seto-Young, D., Jul 1 2016, In: Hormone and Metabolic Research. 48, 7, p. 468-475 8 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
2015
Honokiol abrogates leptin-induced tumor progression by inhibiting Wnt1-MTA1-β-catenin signaling axis in a microRNA-34a dependent manner
Avtanski, D. B., Nagalingam, A., Kuppusamy, P., Bonner, M. Y., Arbiser, J. L., Saxena, N. K. & Sharma, D., 2015, In: Oncotarget. 6, 18, p. 16396-16410 15 p.Research output: Contribution to journal › Article › peer-review
Open Access42 Scopus citations -
Honokiol activates LKB1-miR-34a axis and antagonizes the oncogenic actions of leptin in breast cancer
Avtanski, D. B., Nagalingam, A., Bonner, M. Y., Arbiser, J. L., Saxena, N. K. & Sharma, D., 2015, In: Oncotarget. 6, 30, p. 29947-29962 16 p.Research output: Contribution to journal › Article › peer-review
Open Access33 Scopus citations -
2014
Honokiol inhibits epithelial-mesenchymal transition in breast cancer cells by targeting signal transducer and activator of transcription 3/Zeb1/E-cadherin axis
Avtanski, D. B., Nagalingam, A., Bonner, M. Y., Arbiser, J. L., Saxena, N. K. & Sharma, D., May 2014, In: Molecular oncology. 8, 3, p. 565-580 16 p.Research output: Contribution to journal › Article › peer-review
Open Access66 Scopus citations -
Mechanistic elucidation of the antitumor properties of withaferin a in breast cancer
Nagalingam, A., Kuppusamy, P., Singh, S. V., Sharma, D. & Saxena, N. K., Jan 5 2014, In: Cancer Research. 74, 9, p. 2617-2629 13 p.Research output: Contribution to journal › Article › peer-review
Open Access49 Scopus citations -
2013
Big punches come in nanosizes for chemoprevention
Sharma, D. & Sukumar, S., Oct 2013, In: Cancer Prevention Research. 6, 10, p. 1007-1010 4 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Integral role of PTP1B in adiponectin-mediated inhibition of oncogenic actions of leptin in breast carcinogenesis
Taliaferro-Smith, L. T., Nagalingam, A., Knight, B. B., Oberlick, E., Saxena, N. K. & Sharma, D., Jan 2013, In: Neoplasia (United States). 15, 1, p. 23-38 16 p.Research output: Contribution to journal › Article › peer-review
Open Access36 Scopus citations -
Multifaceted leptin network: The molecular connection between obesity and breast cancer
Saxena, N. K. & Sharma, D., Dec 2013, In: Journal of Mammary Gland Biology and Neoplasia. 18, 3-4, p. 309-320 12 p.Research output: Contribution to journal › Article › peer-review
Open Access40 Scopus citations -
2012
Comprehensive evaluation of anti-hyperglycemic activity of fractionated momordica charantia seed extract in alloxan-induced diabetic rats
Choudhary, S. K., Chhabra, G., Sharma, D., Vashishta, A., Ohri, S. & Dixit, A., 2012, In: Evidence-based Complementary and Alternative Medicine. 2012, 293650.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
Honokiol activates AMP-activated protein kinase in breast cancer cells via an LKB1-dependent pathway and inhibits breast carcinogenesis
Nagalingam, A., Arbiser, J. L., Bonner, M. Y., Saxena, N. K. & Sharma, D., Feb 21 2012, In: Breast Cancer Research. 14, 1, R35.Research output: Contribution to journal › Article › peer-review
Open Access67 Scopus citations -
Leptin-induced epithelial-mesenchymal transition in breast cancer cells requires β-catenin activation via Akt/GSK3- and MTA1/Wnt1 protein-dependent pathways
Yan, D., Avtanski, D., Saxena, N. K. & Sharma, D., Mar 9 2012, In: Journal of Biological Chemistry. 287, 11, p. 8598-8612 15 p.Research output: Contribution to journal › Article › peer-review
Open Access136 Scopus citations -
Med1 plays a critical role in the development of tamoxifen resistance
Nagalingam, A., Tighiouart, M., Ryden, L., Joseph, L., Landberg, G., Saxena, N. K. & Sharma, D., Apr 2012, In: Carcinogenesis. 33, 4, p. 918-930 13 p.Research output: Contribution to journal › Article › peer-review
Open Access41 Scopus citations -
2011
Benzyl isothiocyanate inhibits oncogenic actions of leptin in human breast cancer cells by suppressing activation of signal transducer and activator of transcription 3
Kim, S. H., Nagalingam, A., Saxena, N. K., Singh, S. V. & Sharma, D., Mar 2011, In: Carcinogenesis. 32, 3, p. 359-367 9 p.Research output: Contribution to journal › Article › peer-review
Open Access58 Scopus citations -
Survivin upregulation, dependent on leptin-EGFR-Notch1 axis, is essential for leptin-induced migration of breast carcinoma cells
Knight, B. B., Oprea-Ilies, G. M., Nagalingam, A., Yang, L., Cohen, C., Saxena, N. K. & Sharma, D., Aug 2011, In: Endocrine-related cancer. 18, 4, p. 413-428 16 p.Research output: Contribution to journal › Article › peer-review
Open Access61 Scopus citations -
2010
Adiponectin antagonizes the oncogenic actions of leptin in hepatocellular carcinogenesis
Sharma, D., Wang, J., Fu, P. P., Sharma, S., Nagalingam, A., Mells, J., Handy, J., Page, A. J., Cohen, C., Anania, F. A. & Saxena, N. K., Nov 2010, In: Hepatology. 52, 5, p. 1713-1722 10 p.Research output: Contribution to journal › Article › peer-review
Open Access133 Scopus citations -
Adiponectin modulates C-Jun N-terminal kinase and mammalian target of rapamycin and inhibits hepatocellular carcinoma
Saxena, N. K., Fu, P. P., Nagalingam, A., Wang, J., Handy, J., Cohen, C., Tighiouart, M., Sharma, D. & Anania, F. A., Nov 2010, In: Gastroenterology. 139, 5, p. 1762-1773.e5Research output: Contribution to journal › Article › peer-review
123 Scopus citations -
Reciprocal regulation of ZEB1 and AR in triple negative breast cancer cells
Graham, T. R., Yacoub, R., Taliaferro-Smith, L., Osunkoya, A. O., Odero-Marah, V. A., Liu, T., Kimbro, K. S., Sharma, D. & O'Regan, R. M., Aug 2010, In: Breast Cancer Research and Treatment. 123, 1, p. 139-147 9 p.Research output: Contribution to journal › Article › peer-review
Open Access60 Scopus citations -
2009
LKB1 is required for adiponectin-mediated modulation of AMPK-S6K axis and inhibition of migration and invasion of breast cancer cells
Taliaferro-Smith, L., Nagalingam, A., Zhong, D., Zhou, W., Saxena, N. K. & Sharma, D., Jul 23 2009, In: Oncogene. 28, 29, p. 2621-2633 13 p.Research output: Contribution to journal › Article › peer-review
Open Access119 Scopus citations -
2008
Bidirectional crosstalk between leptin and insulin-like growth factor-I signaling promotes invasion and migration of breast cancer cells via transactivation of epidermal growth factor receptor
Saxena, N. K., Taliaferro-Smith, L. T., Knight, B. B., Merlin, D., Anania, F. A., O'Regan, R. M. & Sharma, D., Dec 1 2008, In: Cancer Research. 68, 23, p. 9712-9722 11 p.Research output: Contribution to journal › Article › peer-review
Open Access156 Scopus citations -
Regulation of Estrogen Receptor α by the SET7 Lysine Methyltransferase
Subramanian, K., Jia, D., Kapoor-Vazirani, P., Powell, D. R., Collins, R. E., Sharma, D., Peng, J., Cheng, X. & Vertino, P. M., May 9 2008, In: Molecular cell. 30, 3, p. 336-347 12 p.Research output: Contribution to journal › Article › peer-review
Open Access197 Scopus citations -
2007
Concomitant activation of the JAK/STAT, PI3K/AKT, and ERK signaling is involved in leptin-mediated promotion of invasion and migration of hepatocellular carcinoma cells
Saxena, N. K., Sharma, D., Ding, X., Lin, S., Marra, F., Merlin, D. & Anania, F. A., Mar 15 2007, In: Cancer Research. 67, 6, p. 2497-2507 11 p.Research output: Contribution to journal › Article › peer-review
Open Access379 Scopus citations -
Leptin-induced growth stimulation of breast cancer cells involves recruitment of histone acetyltransferases and mediator complex to CYCLIN D1 promoter via activation of Stat3
Saxena, N. K., Vertino, P. M., Anania, F. A. & Sharma, D., May 4 2007, In: Journal of Biological Chemistry. 282, 18, p. 13316-13325 10 p.Research output: Contribution to journal › Article › peer-review
Open Access143 Scopus citations -
2006
Leptin promotes the proliferative response and invasiveness in human endometrial cancer cells by activating multiple signal-transduction pathways
Sharma, D., Saxena, N. K., Vertino, P. M. & Anania, F. A., Jun 2006, In: Endocrine-related cancer. 13, 2, p. 629-640 12 p.Research output: Contribution to journal › Article › peer-review
Open Access118 Scopus citations -
Restoration of tamoxifen sensitivity in estrogen receptor-negative breast cancer cells: Tamoxifen-bound reactivated ER recruits distinctve corepressor complexes
Sharma, D., Saxena, N. K., Davidson, N. E. & Vertino, P. M., Jun 15 2006, In: Cancer Research. 66, 12, p. 6370-6378 9 p.Research output: Contribution to journal › Article › peer-review
Open Access157 Scopus citations