Dean MacKinnon

2023

Polygenic risk prediction: why and when out-of-sample prediction R² can exceed SNP-based heritability

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Jul 6 2023, In: American journal of human genetics. 110, 7, p. 1207-1215 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2022

Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Eating Disorders Working Group of the Psychiatric Genomics Consortium, German Borderline Genomics Consortium, MVP Suicide Exemplar Workgroup & VA Million Veteran Program, Feb 1 2022, In: Biological psychiatry. 91, 3, p. 313-327 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Identifying the Common Genetic Basis of Antidepressant Response

GSRD Consortium & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Apr 2022, In: Biological Psychiatry Global Open Science. 2, 2, p. 115-126 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders

iPSYCH, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium & Sex Differences Cross-Disorder Analysis Group of the Psychiatric Genomics Consortium, Jan 1 2022, In: Biological psychiatry. 91, 1, p. 102-117 16 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2021

A Comparison of Ten Polygenic Score Methods for Psychiatric Disorders Applied Across Multiple Cohorts

Schizophrenia Working Group of the Psychiatric Genomics Consortium & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Nov 1 2021, In: Biological psychiatry. 90, 9, p. 611-620 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Association of polygenic score for major depression with response to lithium in patients with bipolar disorder

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Jun 1 2021, In: Molecular psychiatry. 26, 6, p. 2457-2470 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

7 Scopus citations

Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium & Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Apr 1 2021, In: Molecular psychiatry. 26, 4, p. 1286-1298 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

2020

A phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Dec 1 2020, In: Nature communications. 11, 1, 2301.

Research output: Contribution to journal › Article › peer-review

Open Access

7 Scopus citations

Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Mar 1 2020, In: Biological psychiatry. 87, 5, p. 419-430 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Jul 1 2020, In: Molecular psychiatry. 25, 7, p. 1430-1446 17 p.

Research output: Contribution to journal › Article › peer-review

Open Access

20 Scopus citations

The Genetics of the Mood Disorder Spectrum: Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls

Bipolar Disorder Working Group of the Psychiatric Genomics Consortium & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Jul 15 2020, In: Biological psychiatry. 88, 2, p. 169-184 16 p.

Research output: Contribution to journal › Article › peer-review

Open Access

24 Scopus citations

2019

Assessment of bidirectional relationships between physical activity and depression among adults a 2-sample Mendelian randomization study

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Apr 2019, In: JAMA psychiatry. 76, 4, p. 399-408 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

94 Scopus citations

Association of Whole-Genome and NETRIN1 Signaling Pathway–Derived Polygenic Risk Scores for Major Depressive Disorder and White Matter Microstructure in the UK Biobank

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium & 23andMe Research Team, Jan 2019, In: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. 4, 1, p. 91-100 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

9 Scopus citations

Identification of common genetic risk variants for autism spectrum disorder

Autism Spectrum Disorder Working Group of the Psychiatric Genomics Consortium, BUPGEN, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium & 23andMe Research Team, Mar 1 2019, In: Nature genetics. 51, 3, p. 431-444 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

373 Scopus citations

Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Dec 1 2019, In: Nature communications. 10, 1, 2548.

Research output: Contribution to journal › Article › peer-review

Open Access

28 Scopus citations

2018

Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder

Major Depressive Disorder and Bipolar Disorder Working Groups of the Psychiatric Genomics Consortium, Dec 1 2018, In: Communications biology. 1, 1, 163.

Research output: Contribution to journal › Article › peer-review

Open Access

7 Scopus citations

Change in Medical Student Attitudes Toward Patients with Substance Use Disorders After Course Exposure

Koyi, M., Nelliot, A., MacKinnon, D., Rastegar, D. A., Fingerhood, M., Alvanzo, A., Feldman, L. & Neufeld, K. J., Apr 1 2018, In: Academic Psychiatry. 42, 2, p. 283-287 5 p.

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Does Childhood Trauma Moderate Polygenic Risk for Depression? A Meta-analysis of 5765 Subjects From the Psychiatric Genomics Consortium

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Jul 15 2018, In: Biological psychiatry. 84, 2, p. 138-147 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

39 Scopus citations

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

Wray, N. R., Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Adams, M. J., Agerbo, E., Air, T. M., Andlauer, T. M. F., Bacanu, S. A., Bækvad-Hansen, M., Beekman, A. F. T., Bigdeli, T. B., Binder, E. B., Blackwood, D. R. H., Bryois, J., Buttenschøn, H. N., Bybjerg-Grauholm, J., Cai, N., & 196 othersCastelao, E., Christensen, J. H., Clarke, T. K., Coleman, J. I. R., Colodro-Conde, L., Couvy-Duchesne, B., Craddock, N., Crawford, G. E., Crowley, C. A., Dashti, H. S., Davies, G., Deary, I. J., Degenhardt, F., Derks, E. M., DIrek, N., Dolan, C. V., Dunn, E. C., Eley, T. C., Eriksson, N., Escott-Price, V., Kiadeh, F. H. F., Finucane, H. K., Forstner, A. J., Frank, J., Gaspar, H. A., Gill, M., Giusti-Rodríguez, P., Goes, F. S., Gordon, S. D., Grove, J., Hall, L. S., Hannon, E., Hansen, C. S., Hansen, T. F., Herms, S., Hickie, I. B., Hoffmann, P., Homuth, G., Horn, C., Hottenga, J. J., Hougaard, D. M., Hu, M., Hyde, C. L., Ising, M., Jansen, R., Jin, F., Jorgenson, E., Knowles, J. A., Kohane, I. S., Kraft, J., Kretzschmar, W. W., Krogh, J., Kutalik, Z., Lane, J. M., Li, Y., Li, Y., Lind, P. A., Liu, X., Lu, L., MacIntyre, D. J., MacKinnon, D. F., Maier, R. M., Maier, W., Marchini, J., Mbarek, H., McGrath, P., McGuffin, P., Medland, S. E., Mehta, DI., Middeldorp, C. M., Mihailov, E., Milaneschi, Y., Milani, L., Mill, J., Mondimore, F. M., Montgomery, G. W., Mostafavi, S., Mullins, N., Nauck, M., Ng, B., Nivard, M. G., Nyholt, D. R., O'Reilly, P. F., Oskarsson, H., Owen, M. J., Painter, J. N., Pedersen, C. B., Pedersen, M. G., Peterson, R. E., Pettersson, E., Peyrot, W. J., Pistis, G., Posthuma, D., Purcell, S. M., Quiroz, J. A., Qvist, P., Rice, J. P., Riley, B. P., Rivera, M., Saeed Mirza, S., Saxena, R., Schoevers, R., Schulte, E. C., Shen, L., Shi, J., Shyn, S. I., Sigurdsson, E., Sinnamon, G. B. C., Smit, J. H., Smith, D. J., Stefansson, H., Steinberg, S., Stockmeier, C. A., Streit, F., Strohmaier, J., Tansey, K. E., Teismann, H., Teumer, A., Thompson, W., Thomson, P. A., Thorgeirsson, T. E., Tian, C., Traylor, M., Treutlein, J., Trubetskoy, V., Uitterlinden, A. G., Umbricht, D., Van Der Auwera, S., Van Hemert, A. M., Viktorin, A., Visscher, P. M., Wang, Y., Webb, B. T., Weinsheimer, S. M., Wellmann, J., Willemsen, G., Witt, S. H., Wu, Y., Xi, H. S., Yang, J., Zhang, F., Arolt, V., Baune, B. T., Berger, K., Boomsma, D. I., Cichon, S., Dannlowski, U., De Geus, E. C. J., Depaulo, J. R., Domenici, E., Domschke, K., Esko, T., Grabe, H. J., Hamilton, S. P., Hayward, C., Heath, A. C., Hinds, D. A., Kendler, K. S., Kloiber, S., Lewis, G., Li, Q. S., Lucae, S., Madden, P. F. A., Magnusson, P. K., Martin, N. G., McIntosh, A. M., Metspalu, A., Mors, O., Mortensen, P. B., Müller-Myhsok, B., Nordentoft, M., Nöthen, M. M., O'Donovan, M. C., Paciga, S. A., Pedersen, N. L., Penninx, B. W. J. H., Perlis, R. H., Porteous, D. J., Potash, J. B., Preisig, M., Rietschel, M., Schaefer, C., Schulze, T. G., Smoller, J. W., Stefansson, K., Tiemeier, H., Uher, R., Völzke, H., Weissman, M. M., Werge, T., Winslow, A. R., Lewis, C. M., Levinson, D. F., Breen, G., Børglum, A. D. & Sullivan, P. F., May 1 2018, In: Nature genetics. 50, 5, p. 668-681 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

777 Scopus citations

Genome-wide interaction study of a proxy for stress-sensitivity and its prediction of major depressive disorder

Generation Scotland & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Dec 2018, In: PloS one. 13, 12, e0209160.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

2017

Genetic association of major depression with a typical features and obesity-related immunometabolic dysregulations

CHARGE InflammationWorking Group and the Major Depressive DisorderWorking Group of the Psychiatric Genomics Consortium, Dec 2017, In: JAMA psychiatry. 74, 12, p. 1214-1225 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

77 Scopus citations

2016

The "hard" and "soft" phenotypic boundaries of bipolar disorder

Mackinnon, D. F., Aug 1 2016, In: Psychiatric Times. 33, 8

Research output: Contribution to journal › Article › peer-review

2015

Distinguishing bipolar from unipolar depression: The importance of clinical symptoms and illness features

Leonpacher, A. K., Liebers, D., Pirooznia, M., Jancic, D., Mackinnon, D. F., Mondimore, F. M., Schweizer, B., Potash, J. B., Zandi, P. P. & Goes, F. S., May 4 2015, In: Psychological medicine. 45, 11, p. 2437-2446 10 p.

Research output: Contribution to journal › Article › peer-review

27 Scopus citations

Test-retest reliability of a new questionnaire for the retrospective assessment of long-term lithium use in bipolar disorder

Tighe, S. K., Ritchey, M., Schweizer, B., Goes, F. S., Mackinnon, D., Mondimore, F., Raymond Depaulo, J., McMahon, F. J., Schulze, T. G., Zandi, P. P. & Potash, J. B., Feb 1 2015, In: Journal of Affective Disorders. 174, p. 589-593 5 p.

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

2014

Delirium presenting as mania in a patient with end-stage COPD

Wilkinson, S. T., Chang, S. B., Foley, T., Lipsey, J. R. & MacKinnon, D. F., 2014, In: American Journal of Psychiatry. 171, 8, p. 821-824 4 p.

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Type I interferon signaling genes in recurrent major depression: Increased expression detected by whole-blood RNA sequencing

Mostafavi, S., Battle, A., Zhu, X., Potash, J. B., Weissman, M. M., Shi, J., Beckman, K., Haudenschild, C., Mccormick, C., Mei, R., Gameroff, M. J., Gindes, H., Adams, P., Goes, F. S., Mondimore, F. M., Mackinnon, D. F., Notes, L., Schweizer, B., Furman, D., Montgomery, S. B., & 3 othersUrban, A. E., Koller, D. & Levinson, D. F., Dec 11 2014, In: Molecular psychiatry. 19, 12, p. 1267-1274 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

84 Scopus citations

2013

Posttraumatic stress disorder increases risk for suicide attempt in adults with recurrent major depression

Stevens, D., Wilcox, H. C., Mackinnon, D. F., Mondimore, F. M., Schweizer, B., Jancic, D., Coryell, W. H., Weissman, M. M., Levinson, D. F. & Potash, J. B., Oct 2013, In: Depression and anxiety. 30, 10, p. 940-946 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

28 Scopus citations

2012

A collaborative approach to teaching medical students how to screen, intervene, and treat substance use disorders

Neufeld, K. J., Alvanzo, A., King, V., Feldman, L., Hsu, J. H., Rastegar, D. A., Colbert, J. M. & MacKinnon, D. F., Jul 1 2012, In: Substance Abuse. 33, 3, p. 286-291 6 p.

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

A genome-wide association study of attempted suicide

Willour, V. L., Seifuddin, F., Mahon, P. B., Jancic, D., Pirooznia, M., Steele, J., Schweizer, B., Goes, F. S., Mondimore, F. M., MacKinnon, D. F., Perlis, R. H., Lee, P. H., Huang, J., Kelsoe, J. R., Shilling, P. D., Rietschel, M., Nöthen, M., Cichon, S., Gurling, H., Purcell, S., & 7 othersSmoller, J. W., Craddock, N., DePaulo, J. R., Schulze, T. G., McMahon, F. J., Zandi, P. P. & Potash, J. B., Apr 2012, In: Molecular psychiatry. 17, 4, p. 433-444 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

96 Scopus citations

Association study of serotonin pathway genes in attempted suicide

Judy, J. T., Seifuddin, F., Mahon, P. B., Huo, Y., Goes, F. S., Jancic, D., Schweizer, B., Mondimore, F. M., Mackinnon, D. F., Depaulo, J. R., Gershon, E. S., Mcmahon, F. J., Cutler, D. J., Zandi, P. P., Potash, J. B. & Willour, V. L., Jan 2012, In: American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 159 B, 1, p. 112-119 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

16 Scopus citations

Co-morbid anxiety disorders in bipolar disorder and major depression: Familial aggregation and clinical characteristics of co-morbid panic disorder, social phobia, specific phobia and obsessive-compulsive disorder

Goes, F. S., McCusker, M. G., Bienvenu, O. J., MacKinnon, D. F., Mondimore, F. M., Schweizer, B., Depaulo, J. R. & Potash, J. B., Jul 2012, In: Psychological medicine. 42, 7, p. 1449-1459 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

86 Scopus citations

2011

Genetic association of bipolar disorder with the β₃ nicotinic receptor subunit gene

NIMH Genetics Initiative Bipolar Disorder Consortium, Apr 2011, In: Psychiatric genetics. 21, 2, p. 77-84 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

6 Scopus citations

2010

An investigation of candidate regions for association with bipolar disorder

NIMH Genetics Initiative Bipolar Disorder Consortium, NIMH Genetics Initiative Bipolar Disorder Consortium, NIMH Genetics Initiative Bipolar Disorder Consortium, NIMH Genetics Initiative Bipolar Disorder Consortium, NIMH Genetics Initiative Bipolar Disorder Consortium, NIMH Genetics Initiative Bipolar Disorder Consortium, NIMH Genetics Initiative Bipolar Disorder Consortium, NIMH Genetics Initiative Bipolar Disorder Consortium, NIMH Genetics Initiative Bipolar Disorder Consortium & NIMH Genetics Initiative Bipolar Disorder Consortium, Oct 1 2010, In: American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 153, 7, p. 1292-1297 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

Sex-specific association of the reelin gene with bipolar disorder

Goes, F. S., Willour, V. L., Zandi, P. P., Belmonte, P. L., MacKinnon, D. F., Mondimore, F. M., Schweizer, B., DePaulo, J. R., Gershon, E. S., McMahon, F. J. & Potash, J. B., Mar 2010, In: American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 153, 2, p. 549-553 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

46 Scopus citations

2009

Carbon dioxide induces erratic respiratory responses in bipolar disorder

MacKinnon, D. F., Craighead, B. & Lorenz, L., Jan 2009, In: Journal of Affective Disorders. 112, 1-3, p. 193-200 8 p.

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Family-based association of FKBP5 in bipolar disorder

Willour, V. L., Chen, H., Toolan, J., Belmonte, P., Cutler, D. J., Goes, F. S., Zandi, P. P., Lee, R. S., MacKinnon, D. F., Mondimore, F. M., Schweizer, B., DePaulo, J. R., Gershon, E., McMahon, F. J., Potash, J. B., Miller, E., Pearl, J., Kassem, L., Lopez, V., Nurnberger, J., & 46 othersMiller, M. J., Bowman, E. S., Reich, T., Goate, A., Rice, J., Stine, C., Kazuba, D., Maxwell, E., Rau, N. L., Moe, P. R., Samavedy, N., El-Mallakh, R., Manji, H., Glitz, D. A., Meyer, E. T., Smiley, C., Foroud, T., Flury, L., Dick, D. M., Edenberg, H., Bierut, L., McInnis, M., Avramopoulos, D., Payne, J., Berrettini, W., Byerley, W., Vawter, M., Coryell, W., Crowe, R., Badner, J., Liu, C., Sanders, A., Caserta, M., Dinwiddie, S., Nguyen, T., Harakal, D., Kelsoe, J., McKinney, R., Scheftner, W., Kravitz, H. M., Marta, D., Vaughn-Brown, A., Bederow, L., Detera-Wadleigh, S., Austin, L. & Murphy, D. L., Jan 1 2009, In: Molecular psychiatry. 14, 3, p. 261-268 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

128 Scopus citations

Family-based association of YWHAH in psychotic bipolar disorder

Grover, D., Verma, R., Goes, F. S., Belmonte Mahon, P. L., Gershon, E. S., McMahon, F. J., Potash, J. B., Steele, J., Kassem, L., Pearl, J., Schulze, T., MacKinnon, D. F., Miller, E., Toolan, J., Zandi, P. P., Simpson, S., Nurnberger, J., Miller, M. J., Bowman, E. S., Reich, T., & 45 othersGoate, A., Rice, J., DePaulo, J. R., Stine, C., Kazuba, D., Maxwell, E., Rau, N. L., Moe, P. R., Samavedy, N., El-Mallakh, R., Manji, H., Glitz, D. A., Meyer, E. T., Smiley, C., Foroud, T., Flury, L., Dick, D. M., Edenberg, H., Bierut, L., McInnis, M., Mondimore, F. M., Avramopoulos, D., Payne, J., Berrettini, W., Byerley, W., Vawter, M., Coryell, W., Crowe, R., Badner, J., Liu, C., Sanders, A., Caserta, M., Dinwiddie, S., Nguyen, T., Harakal, D., Kelsoe, J., McKinney, R., Scheftner, W., Kravitz, H. M., Marta, D., Vaughn-Brown, A., Bederow, L., Detera-Wadleigh, S., Austin, L. & Murphy, D. L., Oct 5 2009, In: American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 150, 7, p. 977-983 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

38 Scopus citations

Family-based association study of neuregulin 1 with psychotic bipolar disorder

Goes, F. S., Willour, V. L., Zandi, P. P., Belmonte, P. L., MacKinnon, D. F., Mondimore, F. M., Schweizer, B., Gershon, E. S., McMahon, F. J. & Potash, J. B., Jul 5 2009, In: American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 150, 5, p. 693-702 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

29 Scopus citations

Genome-wide linkage and follow-up association study of postpartum mood symptoms

NIMH Bipolar Disorder Genetics Initiative, the "Molecular Genetics of Schizophrenia II" (MGS-2) collaboration, Bipolar Genetics Studies (BiGS) Collaboration & NIMH Genetics of Recurrent Early-Onset Depression (GenRED) project, Nov 1 2009, In: American Journal of Psychiatry. 166, 11, p. 1229-1237 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

65 Scopus citations

Premenstrual mood symptoms: Study of familiality and personality correlates in mood disorder pedigrees

NIMH Genetics Initiative Bipolar Disorder Consortium, Feb 1 2009, In: Archives of Women's Mental Health. 12, 1, p. 27-34 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

9 Scopus citations

2008

Association study of Wnt signaling pathway genes in bipolar disorder

Zandi, P. P., Belmonte, P. L., Willour, V. L., Goes, F. S., Badner, J. A., Simpson, S. G., Gershon, E. S., McMahon, F. J., DePaulo, J. R., Potash, J. B., Steele, J., Pearl, J., Kassem, L., Lopez, V., MacKinnon, D., Miller, E., Toolan, J., Schulze, T., Byerley, W., Coryell, W., & 3 othersKelsoe, J., Rice, J. & Nurnberger, J., Jul 2008, In: Archives of general psychiatry. 65, 7, p. 785-793 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

57 Scopus citations

Bipolar disorder as maladaptive arousal

MacKinnon, D. F., May 2008, In: Annals of the New York Academy of Sciences. 1129, p. 185-189 5 p.

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Evidence of association between brain-derived neurotrophic factor gene and bipolar disorder

Liu, L., Foroud, T., Xuei, X., Berrettini, W., Byerley, W., Coryell, W., El-Mallakh, R., Gershon, E. S., Kelsoe, J. R., Lawson, W. B., MacKinnon, D. F., McInnis, M., McMahon, F. J., Murphy, D. L., Rice, J., Scheftner, W., Zandi, P. R., Lohoff, F. W., Niculescu, A. B., Meyer, E. T., & 2 othersEdenberg, H. J. & Nurnberger, J. I., Dec 2008, In: Psychiatric genetics. 18, 6, p. 267-274 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

46 Scopus citations

Familial aggregation of postpartum mood symptoms in bipolar disorder pedigrees

Payne, J. L., Mackinnon, D. F., Mondimore, F. M., Mcinnis, M. G., Schweizer, B., Zamoiski, R. B., Mcmahon, F. J., Nurnberger, J. I., Rice, J. P., Scheftner, W., Coryell, W., Berrettini, W. H., Kelsoe, J. R., Byerley, W., Gershon, E. S., Depaulo, J. R. & Potash, J. B., Feb 2008, In: Bipolar Disorders. 10, 1, p. 38-44 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

35 Scopus citations

Rapid switching of mood in families with familial bipolar disorder

Nwulia, E. A., Zandi, P. P., McInnis, M. G., DePaulo, J. R. & MacKinnon, D. F., Aug 2008, In: Bipolar Disorders. 10, 5, p. 597-606 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Scopus citations

2007

A comparison of the familiality of chronic depression in recurrent early-onset depression pedigrees using different definitions of chronicity

Mondimore, F. M., Zandi, P. P., MacKinnon, D. F., McInnis, M. G., Miller, E. B., Schweizer, B., Crowe, R. P., Scheftner, W. A., Weissman, M. M., Levinson, D. F., DePaulo, J. R. & Potash, J. B., Jun 2007, In: Journal of Affective Disorders. 100, 1-3, p. 171-177 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

15 Scopus citations

Attempted Suicide in Bipolar Disorder Pedigrees: Evidence for Linkage to 2p12

Willour, V. L., Zandi, P. P., Badner, J. A., Steele, J., Miao, K., Lopez, V., MacKinnon, D. F., Mondimore, F. M., Schweizer, B., McInnis, M. G., Miller, E. B., DePaulo, J. R., Gershon, E. S., McMahon, F. J. & Potash, J. B., Mar 1 2007, In: Biological psychiatry. 61, 5, p. 725-727 3 p.

Research output: Contribution to journal › Article › peer-review

37 Scopus citations

Carbon dioxide provocation of anxiety and respiratory response in bipolar disorder

MacKinnon, D. F., Craighead, B. & Hoehn-Saric, R., Apr 2007, In: Journal of Affective Disorders. 99, 1-3, p. 45-49 5 p.

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Genetics of comorbid mood disorder and alcohol dependence

Nurnberger, J. I., Kuperman, S., Flury-Wetherill, L., Meyer, E. T., Lawson, W. B. & MacKinnon, D. F., Mar 22 2007, In: Journal of Dual Diagnosis. 3, 2, p. 31-46 16 p.

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Genetics of recurrent early-onset major depression (GenRED): Final genome scan report

Holmans, P., Weissman, M. M., Zubenko, G. S., Scheftner, W. A., Crowe, R. R., DePaulo, J. R., Knowles, J. A., Zubenko, W. N., Murphy-Eberenz, K., Marta, D. H., Boutelle, S., Mcinnis, M., Adams, P., Gladis, M., Steele, J., Miller, E. B., Potash, J. B., MacKinnon, D. F. & Levinson, D. F., Feb 2007, In: American Journal of Psychiatry. 164, 2, p. 248-258 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

79 Scopus citations

Dean MacKinnon

Research output

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