Research output per year
Research output per year
- 1 - 50 out of 180 results
Search results
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2024
A randomized double-blind pilot study to evaluate the efficacy, safety, and tolerability of intravenous iron versus oral iron for the treatment of restless legs syndrome in patients with iron deficiency anemia
Short, V., Allen, R., Earley, C. J., Bahrain, H., Rineer, S., Kashi, K., Gerb, J. & Auerbach, M., 2024, (Accepted/In press) In: American journal of hematology.Research output: Contribution to journal › Article › peer-review
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2023
Ferric carboxymaltose effects on restless legs syndrome and on brain iron in patients with iron deficiency anemia
Bae, H., Cho, Y. W., Kim, K. T., Li, X. & Earley, C. J., Sep 2023, In: Sleep Medicine. 109, p. 128-131 4 p.Research output: Contribution to journal › Article › peer-review
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2022
A pilot study to understand the relationship between cortical arousals and leg movements during sleep
Bansal, K., Garcia, J., Feltch, C., Earley, C., Robucci, R., Banerjee, N. & Brooks, J., Dec 2022, In: Scientific reports. 12, 1, 12685.Research output: Contribution to journal › Article › peer-review
Open Access -
Brain Iron Deficiency Changes the Stoichiometry of Adenosine Receptor Subtypes in Cortico-Striatal Terminals: Implications for Restless Legs Syndrome
Rodrigues, M. S., Ferreira, S. G., Quiroz, C., Earley, C. J., García-Borreguero, D., Cunha, R. A., Ciruela, F., Köfalvi, A. & Ferré, S., Mar 1 2022, In: Molecules. 27, 5, 1489.Research output: Contribution to journal › Article › peer-review
Open Access -
RestEaze: An Emerging Technology to Characterize Leg Movements During Sleep
Brooks, J., Feltch, C., Lam, J., Earley, C., Robucci, R., Agarwal, S. & Banerjee, N., Jun 2022, In: Journal of Medical Devices, Transactions of the ASME. 16, 2, 021010.Research output: Contribution to journal › Article › peer-review
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2021
Developing a biomarker for restless leg syndrome using genome wide DNA methylation data
Roy, A., Earley, C. J., Allen, R. P. & Kaminsky, Z. A., Feb 2021, In: Sleep Medicine. 78, p. 120-127 8 p.Research output: Contribution to journal › Article › peer-review
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Effects of new PLM scoring rules on PLM rate in relation to sleep and resting wake for RLS and healthy controls.
Elena, H., Leslie, B., Skeba, P., Wang, A., Earley, C. & Allen, R., Mar 2021, In: Sleep and Breathing. 25, 1, p. 381-386 6 p.Research output: Contribution to journal › Article › peer-review
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Pilot study: can machine learning analyses of movement discriminate between leg movements in sleep (LMS) with vs. without cortical arousals?
Jha, A., Banerjee, N., Feltch, C., Robucci, R., Earley, C. J., Lam, J. & Allen, R., Mar 2021, In: Sleep and Breathing. 25, 1, p. 373-379 7 p.Research output: Contribution to journal › Article › peer-review
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Randomized, placebo-controlled trial of ferric carboxymaltose in restless legs syndrome patients with iron deficiency anemia
Bae, H., Cho, Y. W., Kim, K. T., Allen, R. P. & Earley, C. J., Aug 2021, In: Sleep Medicine. 84, p. 179-186 8 p.Research output: Contribution to journal › Article › peer-review
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The Safety and Efficacy of Pregabalin Add-on Therapy in Restless Legs Syndrome Patients
Bae, H., Cho, Y. W., Kim, K. T., Allen, R. P. & Earley, C. J., Nov 29 2021, In: Frontiers in Neurology. 12, 786408.Research output: Contribution to journal › Article › peer-review
Open Access -
2020
Developing a behavioral model of Restless Legs Syndrome utilizing mice with natural variances in ventral midbrain iron
Earley, C. J., Allen, R. P., Jones, B. C. & Unger, E. L., Jul 2020, In: Sleep Medicine. 71, p. 135-140 6 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Evidence for communication of peripheral iron status to cerebrospinal fluid: Clinical implications for therapeutic strategy
Connor, J. R., Duck, K., Patton, S., Simpson, I. A., Trotti, L. M., Allen, R., Earley, C. J. & Rye, D., Apr 16 2020, In: Fluids and barriers of the CNS. 17, 1, 28.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Iron-deficiency and dopaminergic treatment effects on RLS-Like behaviors of an animal model with the brain iron deficiency pattern of the restless legs syndrome
Allen, R. P., Earley, C. J., Jones, B. C. & Unger, E. L., Jul 2020, In: Sleep Medicine. 71, p. 141-148 8 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
Moderate to severe but not mild RLS is associated with greater sleep-related sympathetic autonomic activation than healthy adults without RLS
Jin, B., Wang, A., Earley, C. & Allen, R., Apr 2020, In: Sleep Medicine. 68, p. 89-95 7 p.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
Resting-state connectivity and the effects of treatment in restless legs syndrome
Lee, Y. S., Ku, J., Kim, K. T., Chang, H. W., Earley, C. J., Allen, R. P. & Cho, Y. W., Mar 2020, In: Sleep Medicine. 67, p. 33-38 6 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
2019
Extracellular vesicles reveal abnormalities in neuronal iron metabolism in restless legs syndrome
Chawla, S., Gulyani, S., Allen, R. P., Earley, C. J., Li, X., Van Zijl, P. & Kapogiannis, DI., Jul 2019, In: Sleep. 42, 7, zsz079.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
2018
A direct interaction between two Restless Legs Syndrome predisposing genes: MEIS1 and SKOR1
Catoire, H., Sarayloo, F., Mourabit Amari, K., Apuzzo, S., Grant, A., Rochefort, D., Xiong, L., Montplaisir, J., Earley, C. J., Turecki, G., Dion, P. A. & Rouleau, G. A., Dec 1 2018, In: Scientific reports. 8, 1, 12173.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
Assessment of change in restless legs syndrome symptoms during the acute drug-withdrawal period
Wang, A., Foster, K., Skeba, P., Hiranniramol, K., Earley, C. J. & Allen, R. P., Dec 2018, In: Sleep Medicine. 52, p. 80-87 8 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Connecting clinical aspects to corticomotor excitability in restless legs syndrome: a TMS study
Salas, R. M. E., Kalloo, A., Earley, C. J., Celnik, P., Cruz, T. E., Foster, K., Cantarero, G. & Allen, R. P., Sep 2018, In: Sleep Medicine. 49, p. 105-112 8 p.Research output: Contribution to journal › Article › peer-review
8 Scopus citations -
Diurnal variation of default mode network in patients with restless legs syndrome
Ku, J., Lee, Y. S., Chang, H. W., Earley, C. J., Allen, R. P. & Cho, Y. W., Jan 2018, In: Sleep Medicine. 41, p. 1-8 8 p.Research output: Contribution to journal › Article › peer-review
8 Scopus citations -
Efficacy of ferric carboxymaltose (FCM) 500 mg dose for the treatment of Restless Legs Syndrome
Cho, Y. W., Allen, R. P. & Earley, C. J., Feb 2018, In: Sleep Medicine. 42, p. 7-12 6 p.Research output: Contribution to journal › Article › peer-review
7 Scopus citations -
Evidence-based and consensus clinical practice guidelines for the iron treatment of restless legs syndrome/Willis-Ekbom disease in adults and children: an IRLSSG task force report
on behalf of the & International Restless Legs Syndrome Study Group (IRLSSG), Jan 2018, In: Sleep Medicine. 41, p. 27-44 18 p.Research output: Contribution to journal › Article › peer-review
Open Access87 Scopus citations -
Pivotal role of adenosine neurotransmission in Restless Legs Syndrome
Ferré, S., Quiroz, C., Guitart, X., Rea, W., Seyedian, A., Moreno, E., Casadó-Anguera, V., Díaz-Ríos, M., Casadó, V., Clemens, S., Allen, R. P., Earley, C. J. & García-Borreguero, D., Jan 8 2018, In: Frontiers in Neuroscience. 11, JAN, 722.Research output: Contribution to journal › Article › peer-review
Open Access24 Scopus citations -
The Appropriate Use of Opioids in the Treatment of Refractory Restless Legs Syndrome
for the & Scientific and Medical Advisory Board, Restless Legs Syndrome Foundation, Jan 2018, In: Mayo Clinic proceedings. 93, 1, p. 59-67 9 p.Research output: Contribution to journal › Article › peer-review
25 Scopus citations -
TOX3 Variants Are Involved in Restless Legs Syndrome and Parkinson’s Disease with Opposite Effects
Mohtashami, S., He, Q., Ruskey, J. A., Zhou, S., Dion, P. A., Allen, R. P., Earley, C. J., Fon, E. A., Xiong, L., Dupre, N., Dauvilliers, Y., Rouleau, G. A. & Gan-Or, Z., Mar 1 2018, In: Journal of Molecular Neuroscience. 64, 3, p. 341-345 5 p.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
2017
Allocating provider resources to diagnose and treat restless legs syndrome: a cost-utility analysis
Padula, W., Phelps, C. E., Moran, D. & Earley, C. J., Oct 1 2017, In: Sleep Medicine. 38, p. 44-49 6 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
Identification of novel risk loci for restless legs syndrome in genome-wide association studies in individuals of European ancestry: a meta-analysis
23andMe Research Team, DESIR study group, 23andMe Research Team, DESIR study group, DESIR study group & DESIR study group, Nov 2017, In: The Lancet Neurology. 16, 11, p. 898-907 10 p.Research output: Contribution to journal › Article › peer-review
Open Access98 Scopus citations -
Intervening leg movements disrupt PLMS sequences
Hiranniramol, K., Fulda, S., Skeba, P., Earley, C. J. & Allen, R. P., Jan 1 2017, In: Sleep. 40, 1Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
Targeting hypersensitive corticostriatal terminals in restless legs syndrome
Yepes, G., Guitart, X., Rea, W., Newman, A. H., Allen, R. P., Earley, C. J., Quiroz, C. & Ferré, S., Dec 2017, In: Annals of neurology. 82, 6, p. 951-960 10 p.Research output: Contribution to journal › Article › peer-review
28 Scopus citations -
2016
Adenosine receptors as markers of brain iron deficiency: Implications for Restless Legs Syndrome
Quiroz, C., Gulyani, S., Ruiqian, W., Bonaventura, J., Cutler, R., Pearson, V., Allen, R. P., Earley, C. J., Mattson, M. P. & Ferré, S., Dec 1 2016, In: Neuropharmacology. 111, p. 160-168 9 p.Research output: Contribution to journal › Article › peer-review
23 Scopus citations -
Brain iron deficiency in idiopathic restless legs syndrome measured by quantitative magnetic susceptibility at 7 tesla
Li, X., Allen, R. P., Earley, C. J., Liu, H., Cruz, T. E., Edden, R. A. E., Barker, P. B. & van Zijl, P. C. M., Jun 1 2016, In: Sleep Medicine. 22, p. 75-82 8 p.Research output: Contribution to journal › Article › peer-review
Open Access48 Scopus citations -
Case–Control and Family-Based Association Study of Specific PTPRD Variants in Restless Legs Syndrome
Gan-Or, Z., Zhou, S., Johnson, A., Montplaisir, J. Y., Allen, R. P., Earley, C. J., Desautels, A., Dion, P. A., Xiong, L. & Rouleau, G. A., Sep 1 2016, In: Movement Disorders Clinical Practice. 3, 5, p. 460-464 5 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Clinical efficacy of ferric carboxymaltose treatment in patients with restless legs syndrome
Cho, Y. W., Allen, R. & Earley, C. J., Sep 1 2016, In: Sleep Medicine. 25, p. 16-23 8 p.Research output: Contribution to journal › Article › peer-review
28 Scopus citations -
Default mode network disturbances in restless legs syndrome/Willis–Ekbom disease
Ku, J., Lee, Y. S., Chang, H. W., Earley, C. J., Allen, R. P. & Cho, Y. W., Jul 1 2016, In: Sleep Medicine. 23, p. 6-11 6 p.Research output: Contribution to journal › Article › peer-review
18 Scopus citations -
Inter-movement interval as a primary stable measure of periodic limb movements of sleep
Skeba, P., Hiranniramol, K., Earley, C. J. & Allen, R. P., 2016, In: Sleep Medicine. 17, p. 138-143 6 p.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
2015
A comparison of MRI tissue relaxometry and ROI methods used to determine regional brain iron concentrations in restless legs syndrome
Moon, H. J., Chang, Y., Lee, Y. S., Song, H., Chang, H. W., Ku, J., Allen, R. P., Earley, C. J. & Cho, Y. W., Jan 1 2015, In: Medical Devices: Evidence and Research. 8, p. 341-350 10 p.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
Analysis of functional GLO1 variants in the BTBD9 locus and restless legs syndrome
Gan-Or, Z., Zhou, S., Ambalavanan, A., Leblond, C. S., Xie, P., Johnson, A., Spiegelman, D., Allen, R. P., Earley, C. J., Desautels, A., Montplaisir, J. Y., Dion, P. A., Xiong, L. & Rouleau, G. A., Sep 1 2015, In: Sleep Medicine. 16, 9, p. 1151-1155 5 p.Research output: Contribution to journal › Article › peer-review
9 Scopus citations -
Co-registration of magnetic resonance spectroscopy and transcranial magnetic stimulation
Hone-Blanchet, A., Salas, R. E., Celnik, P., Kalloo, A., Schar, M., Puts, N. A. J., Harris, A. D., Barker, P. B., Fecteau, S., Earley, C. J., Allen, R. P. & Edden, R. A., Mar 5 2015, In: Journal of Neuroscience Methods. 242, p. 52-57 6 p.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
Gray matter alteration in patients with restless legs syndrome: A voxel-based morphometry study
Chang, Y., Chang, H. W., Song, H., Ku, J., Earley, C. J., Allen, R. P. & Cho, Y. W., Jan 1 2015, In: Clinical Imaging. 39, 1, p. 20-25 6 p.Research output: Contribution to journal › Article › peer-review
23 Scopus citations -
MATPLM1, A MATLAB script for scoring of periodic limb movements: Preliminary validation with visual scoring
Huang, A. S., Skeba, P., Yang, M. S., Sgambati, F. P., Earley, C. J. & Allen, R. P., Dec 2015, In: Sleep Medicine. 16, 12, p. 1541-1549 9 p.Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations -
Prevalence and clinical characteristics of patients with restless legs syndrome with painful symptoms
Cho, Y. W., Song, M. L., Earley, C. J. & Allen, R. P., Jun 1 2015, In: Sleep Medicine. 16, 6, p. 775-778 4 p.Research output: Contribution to journal › Article › peer-review
24 Scopus citations -
2014
Altered white matter integrity in primary restless legs syndrome patients: Diffusion tensor imaging study
Chang, Y., Paik, J. S., Lee, H. J., Chang, H. W., Moon, H. J., Allen, R. P., Earley, C. J. & Cho, Y. W., Aug 2014, In: Neurological research. 36, 8, p. 769-774 6 p.Research output: Contribution to journal › Article › peer-review
19 Scopus citations -
Diurnal variations in brain iron concentrations in BXD RI mice
Unger, E. L., Jones, B. C., Bianco, L. E., Allen, R. P. & Earley, C. J., Mar 28 2014, In: Neuroscience. 263, p. 54-59 6 p.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Functional connectivity alternation of the thalamus in restless legs syndrome patients during the asymptomatic period: A resting-state connectivity study using functional magnetic resonance imaging
Ku, J., Cho, Y. W., Lee, Y. S., Moon, H. J., Chang, H. W., Earley, C. J. & Allen, R. P., Mar 2014, In: Sleep Medicine. 15, 3, p. 289-294 6 p.Research output: Contribution to journal › Article › peer-review
46 Scopus citations -
Low brain iron effects and reversibility on striatal dopamine dynamics
Unger, E. L., Bianco, L. E., Jones, B. C., Allen, R. P. & Earley, C. J., Nov 2014, In: Experimental Neurology. 261, p. 462-468 7 p.Research output: Contribution to journal › Article › peer-review
Open Access33 Scopus citations -
Response to intravenous iron in patients with iron deficiency anemia (IDA) and restless leg syndrome (Willis-Ekbom disease)
Mehmood, T., Auerbach, M., Earley, C. J. & Allen, R. P., Dec 1 2014, In: Sleep Medicine. 15, 12, p. 1473-1476 4 p.Research output: Contribution to journal › Article › peer-review
42 Scopus citations -
Valid measures of periodic leg movements (PLMs) during a suggested immobilization test using the PAM-RL leg activity monitors require adjusting detection parameters for noise and signal in each recording
Yang, M. S., Montplaisir, J., Desautels, A., Winkelman, J. W., Cramer Bornemann, M. A., Earley, C. J. & Allen, R. P., Jan 2014, In: Sleep Medicine. 15, 1, p. 132-137 6 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
2013
Association of restless legs syndrome variants in Korean patients with restless legs syndrome
Kim, M. K., Cho, Y. W., Shin, W. C., Cho, J. W., Shon, Y. M., Kim, J. H., Yang, K. I., Earley, C. J. & Allen, R. P., Dec 1 2013, In: Sleep. 36, 12, p. 1787-1791 5 p.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
Effects of IV iron isomaltoside-1000 treatment on regional brain iron status in an iron-deficient animal
Unger, E. L., Earley, C. J., Thomsen, L. L., Jones, B. C. & Allen, R. P., Aug 29 2013, In: Neuroscience. 246, p. 179-185 7 p.Research output: Contribution to journal › Article › peer-review
14 Scopus citations -
Increased synaptic dopamine in the putamen in restless legs syndrome
Earley, C. J., Kuwabara, H., Wong, D. F., Gamaldo, C., Salas, R. E., Brašíc, J. R., Ravert, H. T., Dannals, R. F. & Allen, R. P., Jan 1 2013, In: Sleep. 36, 1, p. 51-57 7 p.Research output: Contribution to journal › Article › peer-review
Open Access65 Scopus citations