Research output per year
Research output per year
- 1 - 50 out of 94 results
Search results
-
2022
Chromosome-specific telomere lengths and the minimal functional telomere revealed by nanopore sequencing
Sholes, S. L., Karimian, K., Gershman, A., Kelly, T. J., Timp, W. & Greider, C. W., Apr 2022, In: Genome research. 32, 4, p. 616-628 13 p.Research output: Contribution to journal › Article › peer-review
Open Access -
The Bur1 cyclin-dependent kinase regulates telomere length in Saccharomyces cerevisiae
Connelly, C. J., Vidal-Cardenas, S., Goldsmith, S. & Greider, C. W., Mar 2022, In: Yeast. 39, 3, p. 177-192 16 p.Research output: Contribution to journal › Article › peer-review
Open Access -
TPP1 promoter mutations cooperate with TERT promoter mutations to lengthen telomeres in melanoma
Chun-O, P., Hinchie, A. M., Beale, H. C., Silva, A. A. G., Rush, E., Sander, C., Connelly, C. J., Seynnaeve, B. K. N., Kirkwood, J. M., Vaske, O. M., Greider, C. W. & Alder, J. K., Nov 11 2022, In: Science. 378, 6620, p. 664-668 5 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2021
Autoantibodies targeting telomere-associated proteins in systemic sclerosis
Adler, B. L., Boin, F., Wolters, P. J., Bingham, C. O., Shah, A. A., Greider, C., Casciola-Rosen, L. & Rosen, A., Jul 1 2021, In: Annals of the rheumatic diseases. 80, 7, p. 912-919 8 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Rif1 regulates telomere length through conserved HEAT repeats
Shubin, C. B., Mayangsari, R., Swett, A. D. & Greider, C. W., Apr 19 2021, In: Nucleic acids research. 49, 7, p. 3967-3980 14 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2020
The role of rif1 in telomere length regulation is separable from its role in origin firing
Shubin, C. B. & Greider, C. W., Jun 2020, In: eLife. 9, p. 1-40 40 p., e58066.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
2019
Tel1 activation by the MRX complex is sufficient for telomere length regulation but not for the DNA damage response in saccharomyces cerevisiae
Keener, R., Connelly, C. J. & Greider, C. W., 2019, In: Genetics. 213, 4, p. 1271-1288 18 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
TIN2 functions with TPP1/POT1 to stimulate telomerase processivity
Pike, A. M., Strong, M. A., Ouyang, J. P. T. & Greider, C. W., 2019, In: Molecular and cellular biology. 39, 21, e00593-18.Research output: Contribution to journal › Article › peer-review
Open Access15 Scopus citations -
2018
Diagnostic utility of telomere length testing in a hospital-based setting
Alder, J. K., Hanumanthu, V. S., Strong, M. A., DeZern, A. E., Stanley, S. E., Takemoto, C. M., Danilova, L., Applegate, C. D., Bolton, S. G., Mohr, D. W., Brodsky, R. A., Casella, J. F., Greider, C. W., Brooks Jackson, J. & Armanios, M., Mar 6 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 10, p. E2358-E2365Research output: Contribution to journal › Article › peer-review
Open Access64 Scopus citations -
2017
BRD4 inhibitors block telomere elongation
Wang, S., Pike, A. M., Lee, S. S., Strong, M. A., Connelly, C. J. & Greider, C. W., Aug 21 2017, In: Nucleic acids research. 45, 14, p. 8403-8410 8 p.Research output: Contribution to journal › Article › peer-review
Open Access19 Scopus citations -
2016
Regulating telomere length from the inside out: The replication fork model
Greider, C. W., Jul 1 2016, In: Genes and Development. 30, 13, p. 1483-1491 9 p.Research output: Contribution to journal › Article › peer-review
Open Access41 Scopus citations -
2015
ATM Kinase Is Required for Telomere Elongation in Mouse and Human Cells
Lee, S. S., Bohrson, C., Pike, A. M., Wheelan, S. J. & Greider, C. W., Nov 24 2015, In: Cell Reports. 13, 8, p. 1623-1632 10 p.Research output: Contribution to journal › Article › peer-review
Open Access52 Scopus citations -
Regulation of telomere length requires a conserved N-terminal domain of RiF2 in Saccharomyces cerevisiae
Kaizer, H., Connelly, C. J., Bettridge, K., Viggiani, C. & Greider, C. W., Oct 2015, In: Genetics. 201, 2, p. 573-586 14 p.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
2012
Extreme Telomere Length Dimorphism in the Tasmanian Devil and Related Marsupials Suggests Parental Control of Telomere Length
Bender, H. S., Murchison, E. P., Pickett, H. A., Deakin, J. E., Strong, M. A., Conlan, C., McMillan, D. A., Neumann, A. A., Greider, C. W., Hannon, G. J., Reddel, R. R. & Graves, J. A. M., Sep 25 2012, In: PloS one. 7, 9, e46195.Research output: Contribution to journal › Article › peer-review
Open Access18 Scopus citations -
2011
Phenotypes in mTERT+/- and mTERT-/- mice are due to short telomeres, not telomere-independent functions of telomerase reverse transcriptase
Strong, M. A., Vidal-Cardenas, S. L., Karim, B., Yu, H., Guo, N. & Greider, C. W., Jun 2011, In: Molecular and cellular biology. 31, 12, p. 2369-2379 11 p.Research output: Contribution to journal › Article › peer-review
Open Access89 Scopus citations -
2010
A sequence-dependent exonuclease activity from Tetrahymena thermophila
Tom, H. I. K. & Greider, C. W., 2010, In: BMC Biochemistry. 11, 1, 45.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
2009
Comparing effects of mTR and mTERT deletion on gene expression and DNA damage response: A critical examination of telomere length maintenance-independent roles of telomerase
Vidal-Cardenas, S. L. & Greider, C. W., Oct 22 2009, In: Nucleic acids research. 38, 1, p. 60-71 12 p., gkp855.Research output: Contribution to journal › Article › peer-review
Open Access31 Scopus citations -
Kinase-independent functions of TEL1 in telomere maintenance
Ma, Y. & Greider, C. W., Sep 2009, In: Molecular and cellular biology. 29, 18, p. 5193-5202 10 p.Research output: Contribution to journal › Article › peer-review
Open Access19 Scopus citations -
Short Telomeres are Sufficient to Cause the Degenerative Defects Associated with Aging
Armanios, M., Alder, J. K., Parry, E. M., Karim, B., Strong, M. A. & Greider, C. W., Dec 11 2009, In: American journal of human genetics. 85, 6, p. 823-832 10 p.Research output: Contribution to journal › Article › peer-review
Open Access158 Scopus citations -
Short telomeres initiate telomere recombination in primary and tumor cells
Morrish, T. A. & Greider, C. W., Jan 2009, In: PLoS genetics. 5, 1, e1000357.Research output: Contribution to journal › Article › peer-review
Open Access57 Scopus citations -
2007
Short Telomeres Limit Tumor Progression In Vivo by Inducing Senescence
Feldser, D. M. & Greider, C. W., May 8 2007, In: Cancer cell. 11, 5, p. 461-469 9 p.Research output: Contribution to journal › Article › peer-review
Open Access239 Scopus citations -
Telomerase mutations in families with idiopathic pulmonary fibrosis
Armanios, M. Y., Chen, J. J. L., Cogan, J. D., Alder, J. K., Ingersoll, R. G., Markin, C., Lawson, W. E., Xie, M., Vulto, I., Phillips, J. A., Lansdorp, P. M., Greider, C. W. & Loyd, J. E., Mar 29 2007, In: New England Journal of Medicine. 356, 13, p. 1317-1326 10 p.Research output: Contribution to journal › Article › peer-review
Open Access870 Scopus citations -
2006
Ataxia telangiectasia mutated (Atm) is not required for telomerase-mediated elongation of short telomeres
Feldser, D., Strong, M. A. & Greider, C. W., Feb 14 2006, In: Proceedings of the National Academy of Sciences of the United States of America. 103, 7, p. 2249-2251 3 p.Research output: Contribution to journal › Article › peer-review
Open Access19 Scopus citations -
Regulation of Telomere Elongation by the Cyclin-Dependent Kinase CDK1
Frank, C. J., Hyde, M. & Greider, C. W., Nov 3 2006, In: Molecular cell. 24, 3, p. 423-432 10 p.Research output: Contribution to journal › Article › peer-review
Open Access82 Scopus citations -
Telomerase RNA levels limit the telomere length equilibrium
Greider, C. W., 2006, In: Cold Spring Harbor symposia on quantitative biology. 71, p. 225-229 5 p.Research output: Contribution to journal › Article › peer-review
41 Scopus citations -
2005
Functional analysis of the pseudoknot structure in human telomerase RNA
Chen, J. L. & Greider, C. W., Jun 7 2005, In: Proceedings of the National Academy of Sciences of the United States of America. 102, 23, p. 8080-8085 6 p.Research output: Contribution to journal › Article › peer-review
Open Access92 Scopus citations -
Haploinsufficiency of telomerase reverse transcriptase leads to anticipation in autosomal dominant dyskeratosis congenita
Armanios, M., Chen, J. L., Chang, Y. P. C., Brodsky, R. A., Hawkins, A., Griffin, C. A., Eshleman, J. R., Cohen, A. R., Chakravarti, A., Hamosh, A. & Greider, C. W., Nov 1 2005, In: Proceedings of the National Academy of Sciences of the United States of America. 102, 44, p. 15960-15964 5 p.Research output: Contribution to journal › Article › peer-review
Open Access335 Scopus citations -
Short telomeres, even in the presence of telomerase, limit tissue renewal capacity
Hao, L. Y., Armanios, M., Strong, M. A., Karim, B., Feldser, D. M., Huso, D. & Greider, C. W., Dec 16 2005, In: Cell. 123, 6, p. 1121-1131 11 p.Research output: Contribution to journal › Article › peer-review
Open Access224 Scopus citations -
Telomerase and cancer stem cells
Armanios, M. & Greider, C. W., 2005, In: Cold Spring Harbor symposia on quantitative biology. 70, p. 205-208 4 p.Research output: Contribution to journal › Article › peer-review
Open Access63 Scopus citations -
Telomere fusion to chromosome breaks reduces oncogenic translocations and tumour formation
Qi, L., Strong, M. A., Karim, B. O., Huso, D. L. & Greider, C. W., Jul 2005, In: Nature cell biology. 7, 7, p. 706-711 6 p.Research output: Contribution to journal › Article › peer-review
24 Scopus citations -
2004
Genomic instability in both wild-type and telomerase null MEFs
Hao, L. Y. & Greider, C. W., Sep 2004, In: Chromosoma. 113, 2, p. 62-68 7 p.Research output: Contribution to journal › Article › peer-review
10 Scopus citations -
Phosphorylation of H2AX at short telomeres in T cells and fibroblasts
Hao, L. Y., Strong, M. A. & Greider, C. W., Oct 22 2004, In: Journal of Biological Chemistry. 279, 43, p. 45148-45154 7 p.Research output: Contribution to journal › Article › peer-review
Open Access67 Scopus citations -
2003
Determinants in mammalian telomerase RNA that mediate enzyme processivity and cross-species incompatibility
Chen, J. L. & Greider, C. W., Jan 15 2003, In: EMBO Journal. 22, 2, p. 304-314 11 p.Research output: Contribution to journal › Article › peer-review
Open Access110 Scopus citations -
End Resection Initiates Genomic Instability in the Absence of Telomerase
Hackett, J. A. & Greider, C. W., Dec 2003, In: Molecular and cellular biology. 23, 23, p. 8450-8461 12 p.Research output: Contribution to journal › Article › peer-review
Open Access74 Scopus citations -
Short Telomeres and Ataxia-Telangiectasia Mutated Deficiency Cooperatively Increase Telomere Dysfunction and Suppress Tumorigenesis
Qi, L., Strong, M. A., Karim, B. O., Armanios, M., Huso, D. L. & Greider, C. W., Dec 1 2003, In: Cancer Research. 63, 23, p. 8188-8196 9 p.Research output: Contribution to journal › Article › peer-review
56 Scopus citations -
Short telomeres induce a DNA damage response in Saccharomyces cerevisiae
IJpma, A. S. & Greider, C. W., Mar 1 2003, In: Molecular biology of the cell. 14, 3, p. 987-1001 15 p.Research output: Contribution to journal › Article › peer-review
Open Access139 Scopus citations -
Stem-loop IV of Tetrahymena telomerase RNA stimulates processivity in trans
Mason, D. X., Goneska, E. & Greider, C. W., Aug 2003, In: Molecular and cellular biology. 23, 16, p. 5606-5613 8 p.Research output: Contribution to journal › Article › peer-review
54 Scopus citations -
Template boundary definition in mammalian telomerase
Chen, J. L. & Greider, C. W., Nov 15 2003, In: Genes and Development. 17, 22, p. 2747-2752 6 p.Research output: Contribution to journal › Article › peer-review
Open Access117 Scopus citations -
2002
A critical stem-loop structure in the CR4-CR5 domain of mammalian telomerase RNA
Chen, J. L., Opperman, K. K. & Greider, C. W., Jan 15 2002, In: Nucleic acids research. 30, 2, p. 592-597 6 p.Research output: Contribution to journal › Article › peer-review
Open Access121 Scopus citations -
Haploinsufficiency of mTR results in defects in telomere elongation
Hathcock, K. S., Hemann, M. T., Opperman, K. K., Strong, M. A., Greider, C. W. & Hodes, R. J., Mar 19 2002, In: Proceedings of the National Academy of Sciences of the United States of America. 99, 6, p. 3591-3596 6 p.Research output: Contribution to journal › Article › peer-review
Open Access93 Scopus citations -
2001
Telomere dysfunction increases mutation rate and genomic instability
Hackett, J. A., Feldser, D. M. & Greider, C. W., Aug 10 2001, In: Cell. 106, 3, p. 275-286 12 p.Research output: Contribution to journal › Article › peer-review
Open Access289 Scopus citations -
Telomere dysfunction triggers developmentally regulated germ cell apoptosis
Hemann, M. T., Rudolph, K. L., Strong, M. A., DePinho, R. A., Chin, L. & Greider, C. W., 2001, In: Molecular biology of the cell. 12, 7, p. 2023-2030 8 p.Research output: Contribution to journal › Article › peer-review
126 Scopus citations -
Tetrahymena proteins p80 and p95 are not core telomerase components
Mason, D. X., Autexier, C. & Greider, C. W., Oct 23 2001, In: Proceedings of the National Academy of Sciences of the United States of America. 98, 22, p. 12368-12373 6 p.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
The shortest telomere, not average telomere length, is critical for cell viability and chromosome stability
Hemann, M. T., Strong, M. A., Hao, L. Y. & Greider, C. W., Oct 5 2001, In: Cell. 107, 1, p. 67-77 11 p.Research output: Contribution to journal › Article › peer-review
841 Scopus citations -
Two survivor pathways that allow growth in the absence of telomerase are generated by distinct telomere recombination events
Chen, Q., Ijpma, A. & Greider, C. W., 2001, In: Molecular and cellular biology. 21, 5, p. 1819-1827 9 p.Research output: Contribution to journal › Article › peer-review
209 Scopus citations -
2000
Identification of two RNA-binding proteins associated with human telomerase RNA
Le, S., Sternglanz, R. & Greider, C. W., Mar 2000, In: Molecular biology of the cell. 11, 3, p. 999-1010 12 p.Research output: Contribution to journal › Article › peer-review
Open Access110 Scopus citations -
Secondary structure of vertebrate telomerase RNA
Chen, J. L., Blasco, M. A. & Greider, C. W., Mar 3 2000, In: Cell. 100, 5, p. 503-514 12 p.Research output: Contribution to journal › Article › peer-review
Open Access472 Scopus citations -
Telomere length, telomere-binding proteins, and DNA damage signaling
Hemann, M. T., Hackett, J., Ijpma, A. & Greider, C. W., 2000, In: Cold Spring Harbor symposia on quantitative biology. 65, p. 275-279 5 p.Research output: Contribution to journal › Article › peer-review
12 Scopus citations -
Wild-derived inbred mouse strains have short telomeres
Hemann, M. T. & Greider, C. W., Nov 15 2000, In: Nucleic acids research. 28, 22, p. 4474-4478 5 p.Research output: Contribution to journal › Article › peer-review
Open Access171 Scopus citations -
1999
G-strand overhangs on telomeres in telomerase-deficient mouse cells
Hemann, M. T. & Greider, C. W., Oct 15 1999, In: Nucleic acids research. 27, 20, p. 3964-3969 6 p.Research output: Contribution to journal › Article › peer-review
Open Access75 Scopus citations