Calixto-Hope Lucas

Research output

Research output per year 2014 2020 2021 2022 2023 2024

• 33 Article
• 8 Letter
• 5 Review article
• 4 Comment/debate

Research output per year

Research output per year

Search results

• 2024

  Frontal lobe mass in a 46-year-old woman

  Zhang, K. Y., Ramlal, B., Schreck, K. C., Eberhart, C. G. & Lucas, C. H. G., Jan 2024, In: Brain Pathology. 34, 1, e13211.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Preoperative patient-reported physical health-related quality of life predicts short-term postoperative outcomes in brain tumor patients

  Chakravarti, S., Kuo, C. C., Kazemi, F., Kang, A., Lucas, C-H., Croog, V., Kamson, D., Shreck, K. C., Holdhoff, M., Bettegowda, C. & Mukherjee, R., 2024, (Accepted/In press) In: Journal of neuro-oncology.

  Research output: Contribution to journal › Article › peer-review

  • Brain Neoplasms 100%
  • Quality of Life 69%
  • Health 52%
  • Patient Readmission 45%
  • Information Systems 42%
• 2023

  Clinical, histological, and molecular features of gliomas in adults with neurofibromatosis type 1

  Romo, C. G., Piotrowski, A. F., Campian, J. L., Diarte, J., Rodriguez, F. J., Bale, T. A., Dahiya, S., Gutmann, D. H., Lucas, C. H. G., Prichett, L., Mellinghoff, I. & Blakeley, J. O., Aug 1 2023, In: Neuro-oncology. 25, 8, p. 1474-1486 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Neurofibromatosis 1 100%
  • Glioma 75%
  • Astrocytoma 60%
  • Neoplasms 26%
  • Gliosarcoma 20%

• Hypermitotic meningiomas harbor DNA methylation subgroups with distinct biological and clinical features

  Choudhury, A., Chen, W. C., Lucas, C. H. G., Bayley, J. C., Harmanci, A. S., Maas, S. L. N., Santagata, S., Klisch, T., Perry, A., Bi, W. L., Sahm, F., Patel, A. J., Magill, S. T. & Raleigh, D. R., Mar 14 2023, In: Neuro-oncology. 25, 3, p. 520-530 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Meningioma 100%
  • DNA Methylation 91%
  • Neurofibromin 2 23%
  • Molecular Models 19%
  • RNA Sequence Analysis 17%

• Management and Molecular Characterization of Intraventricular Glioblastoma: A Single-Institution Case Series

  Parker, M., Kalluri, A., Materi, J., Gujar, S. K., Schreck, K., Mukherjee, D., Weingart, J., Brem, H., Redmond, K. J., Lucas, C. H. G., Bettegowda, C. & Rincon-Torroella, J., Sep 2023, In: International journal of molecular sciences. 24, 17, 13285.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Intraventricular 100%
  • Tumors 59%
  • Glioblastoma 57%
  • Chromosomes 33%
  • characterization 32%

• Novel SOX10 indel mutations drive schwannomas through impaired transactivation of myelination gene programs

  Williams, E. A., Ravindranathan, A., Gupta, R., Stevers, N. O., Suwala, A. K., Hong, C., Kim, S., Yuan, J. B., Wu, J., Barreto, J., Lucas, C. H. G., Chan, E., Pekmezci, M., Leboit, P. E., Mully, T., Perry, A., Bollen, A., Van Ziffle, J., Devine, W. P., Reddy, A. T., & 21 othersGupta, N., Basnet, K. M., Macaulay, R. J. B., Malafronte, P., Lee, H., Yong, W. H., Williams, K. J., Juratli, T. A., Mata, D. A., Huang, R. S. P., Hiemenz, M. C., Pavlick, D. C., Frampton, G. M., Janovitz, T., Ross, J. S., Chang, S. M., Berger, M. S., Jacques, L., Song, J. S., Costello, J. F. & Solomon, D. A., Dec 1 2023, In: Neuro-oncology. 25, 12, p. 2221-2236 16 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Neurilemmoma 100%
  • Transcriptional Activation 78%
  • Nerve Sheath Neoplasms 52%
  • Mutation 48%
  • Genes 34%

• Radiotherapy and radiosurgery for meningiomas

  Chen, W. C., Lucas, C. H. G., Magill, S. T., Rogers, C. L. & Raleigh, D. R., May 1 2023, In: Neuro-Oncology Advances. 5, p. I67-I83

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Radiosurgery 100%
  • Meningioma 98%
  • Radiotherapy 62%
  • History 17%
  • Central Nervous System 16%

• Targeted gene expression profiling predicts meningioma outcomes and radiotherapy responses

  Chen, W. C., Choudhury, A., Youngblood, M. W., Polley, M. Y. C., Lucas, C. H. G., Mirchia, K., Maas, S. L. N., Suwala, A. K., Won, M., Bayley, J. C., Harmanci, A. S., Harmanci, A. O., Klisch, T. J., Nguyen, M. P., Vasudevan, H. N., McCortney, K., Yu, T. J., Bhave, V., Lam, T. C., Pu, J. K. S., & 38 othersLi, L. F., Leung, G. K. K., Chan, J. W., Perlow, H. K., Palmer, J. D., Haberler, C., Berghoff, A. S., Preusser, M., Nicolaides, T. P., Mawrin, C., Agnihotri, S., Resnick, A., Rood, B. R., Chew, J., Young, J. S., Boreta, L., Braunstein, S. E., Schulte, J., Butowski, N., Santagata, S., Spetzler, D., Bush, N. A. O., Villanueva-Meyer, J. E., Chandler, J. P., Solomon, D. A., Rogers, C. L., Pugh, S. L., Mehta, M. P., Sneed, P. K., Berger, M. S., Horbinski, C. M., McDermott, M. W., Perry, A., Bi, W. L., Patel, A. J., Sahm, F., Magill, S. T. & Raleigh, D. R., Dec 2023, In: Nature medicine. 29, 12, p. 3067-3076 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Meningioma 100%
  • Gene Expression Profiling 95%
  • Biological Marker 83%
  • Area Under the Curve 79%
  • Radiotherapy 63%
• 2022

  Activating NTRK2 and ALK receptor tyrosine kinase fusions extend the molecular spectrum of pleomorphic xanthoastrocytomas of early childhood: a diagnostic overlap with infant-type hemispheric glioma

  Lucas, C. H. G., Abdullaev, Z., Bruggers, C. S., Mirchia, K., Whipple, N. S., Alashari, M. M., Lowichik, A., Cheshier, S., Phillips, J. J., Devine, P., Solomon, D. A., Quezado, M., Aldape, K. D. & Perry, A., Feb 2022, In: Acta neuropathologica. 143, 2, p. 283-286 4 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Giant cell myositis associated with metastatic thymoma and granulomatous hypercalcaemia

  Jimenez, J. C., Lucas, C. H. G., Lahue, S. C. & Sharpe, B. A., Jun 6 2022, In: BMJ case reports. 15, 6, e246688.

  Research output: Contribution to journal › Article › peer-review

  • Myositis 100%
  • Thymoma 99%
  • Hypercalcemia 91%
  • Giant Cells 88%
  • Myasthenia Gravis 38%

• Intratumor and informatic heterogeneity influence meningioma molecular classification

  Vasudevan, H. N., Choudhury, A., Hilz, S., Villanueva-Meyer, J. E., Chen, W. C., Lucas, C. H. G., Braunstein, S. E., Oberheim Bush, N. A., Butowski, N., Pekmezci, M., McDermott, M. W., Perry, A., Solomon, D. A., Magill, S. T. & Raleigh, D. R., Sep 2022, In: Acta neuropathologica. 144, 3, p. 579-583 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Meningioma DNA methylation groups identify biological drivers and therapeutic vulnerabilities

  Choudhury, A., Magill, S. T., Eaton, C. D., Prager, B. C., Chen, W. C., Cady, M. A., Seo, K., Lucas, C. H. G., Casey-Clyde, T. J., Vasudevan, H. N., Liu, S. J., Villanueva-Meyer, J. E., Lam, T. C., Pu, J. K. S., Li, L. F., Leung, G. K. K., Swaney, D. L., Zhang, M. Y., Chan, J. W., Qiu, Z., & 16 othersMartin, M. V., Susko, M. S., Braunstein, S. E., Bush, N. A. O., Schulte, J. D., Butowski, N., Sneed, P. K., Berger, M. S., Krogan, N. J., Perry, A., Phillips, J. J., Solomon, D. A., Costello, J. F., McDermott, M. W., Rich, J. N. & Raleigh, D. R., May 2022, In: Nature genetics. 54, 5, p. 649-659 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Meningioma 100%
  • DNA Methylation 91%
  • Neurofibromin 2 31%
  • Cell Cycle 16%
  • Therapeutics 15%

• Multiplatform molecular analyses refine classification of gliomas arising in patients with neurofibromatosis type 1

  Lucas, C. H. G., Sloan, E. A., Gupta, R., Wu, J., Pratt, D., Vasudevan, H. N., Ravindranathan, A., Barreto, J., Williams, E. A., Shai, A., Whipple, N. S., Bruggers, C. S., Maher, O., Nabors, B., Rodriguez, M., Samuel, D., Brown, M., Carmichael, J., Lu, R., Mirchia, K., & 22 othersSullivan, D. V., Pekmezci, M., Tihan, T., Bollen, A. W., Perry, A., Banerjee, A., Mueller, S., Gupta, N., Hervey-Jumper, S. L., Oberheim Bush, N. A., Daras, M., Taylor, J. W., Butowski, N. A., de Groot, J., Clarke, J. L., Raleigh, D. R., Costello, J. F., Phillips, J. J., Reddy, A. T., Chang, S. M., Berger, M. S. & Solomon, D. A., Oct 2022, In: Acta neuropathologica. 144, 4, p. 747-765 19 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Neurofibromatosis 1 100%
  • Glioma 75%
  • Astrocytoma 22%
  • Epigenomics 17%
  • Neoplasms 13%

• Prospective genomically guided identification of “early/evolving” and “undersampled” IDH-wildtype glioblastoma leads to improved clinical outcomes

  Zhang, Y., Lucas, C. H. G., Young, J. S., Morshed, R. A., McCoy, L., Bush, N. A. O., Taylor, J. W., Daras, M., Butowski, N. A., Villanueva-Meyer, J. E., Cha, S., Wrensch, M., Wiencke, J. K., Lee, J. C., Pekmezci, M., Phillips, J. J., Perry, A., Bollen, A. W., Aghi, M. K., Theodosopoulos, P., & 7 othersChang, E. F., Hervey-Jumper, S. L., Berger, M. S., Clarke, J. L., Chang, S. M., Molinaro, A. M. & Solomon, D. A., Oct 1 2022, In: Neuro-oncology. 24, 10, p. 1749-1762 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Glioblastoma 100%
  • Astrocytoma 64%
  • Epigenomics 25%
  • Standard of Care 14%
  • Glioma 13%

• Resection with intraoperative cesium-131 brachytherapy as salvage therapy for recurrent brain tumors

  Chen, W. C., Lafreniere, M., Phuong, C., Liu, S. J., Baal, J. D., Lometti, M., Morin, O., Ziemer, B., Vasudevan, H. N., Lucas, C. H. G., Hervey-Jumper, S. L., Theodosopoulos, P. V., Magill, S. T., Fogh, S., Nakamura, J. L., Boreta, L., Sneed, P. K., McDermott, M. W., Raleigh, D. R. & Braunstein, S. E., Oct 2022, In: Journal of neurosurgery. 137, 4, p. 924-930 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Cesium-131 100%
  • Salvage Therapy 59%
  • Brachytherapy 55%
  • Brain Neoplasms 46%
  • Radiation Effects 19%

• Targeted Next-Generation Sequencing Reveals Divergent Clonal Evolution in Components of Composite Pleomorphic Xanthoastrocytoma-Ganglioglioma

  Lucas, C. H. G., Davidson, C. J., Alashari, M., Putnam, A. R., Whipple, N. S., Bruggers, C. S., Mendez, J. S., Cheshier, S. H., Walker, J. B., Ramani, B., Cadwell, C. R., Sullivan, D. V., Lu, R., Mirchia, K., Van Ziffle, J., Devine, P., Goldschmidt, E., Hervey-Jumper, S. L., Gupta, N., Bush, N. A. O., & 7 othersRaleigh, D. R., Bollen, A., Tihan, T., Pekmezci, M., Solomon, D. A., Phillips, J. J. & Perry, A., Aug 1 2022, In: Journal of neuropathology and experimental neurology. 81, 8, p. 650-657 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Clonal Evolution 92%
  • High-Throughput Nucleotide Sequencing 63%
  • Cyclin-Dependent Kinase Inhibitor p16 24%
  • Cerebellar Vermis 23%
  • Neoplasms 21%
• 2021

  A prognostic gene-expression signature and risk score for meningioma recurrence after resection

  Chen, W. C., Vasudevan, H. N., Choudhury, A., Pekmezci, M., Lucas, C. H. G., Phillips, J., Magill, S. T., Susko, M. S., Braunstein, S. E., Bush, N. A. O., Boreta, L., Nakamura, J. L., Villanueva-Meyer, J. E., Sneed, P. K., Perry, A., McDermott, M. W., Solomon, D. A., Theodosopoulos, P. V. & Raleigh, D. R., Jan 1 2021, In: Neurosurgery. 88, 1, p. 202-210 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Meningioma 100%
  • Transcriptome 84%
  • Recurrence 52%
  • Genes 22%
  • Gene Expression 11%

• Sarcomatous meningioma: Diagnostic pitfalls and the utility of molecular testing

  Lucas, C. H. G., Devine, P., Solomon, D. A., Giannini, C., Reifenberger, G., Dahiya, S., Caccamo, D. & Perry, A., Aug 1 2021, In: Journal of neuropathology and experimental neurology. 80, 8, p. 764-768 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Meningioma 100%
  • Sarcoma 21%
  • Gene Silencing 12%
  • Diagnostic Errors 11%
  • Histology 9%

• Targeted next-generation sequencing identifies molecular and genetic events in dedifferentiated chondrosarcoma

  Lucas, C. H. G., Grenert, J. P. & Horvai, A., Aug 2021, In: Archives of Pathology and Laboratory Medicine. 145, 8, p. 1009-1017 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Chondrosarcoma 100%
  • High-Throughput Nucleotide Sequencing 76%
  • Molecular Biology 64%
  • Mutation 38%
  • DNA Sequence Analysis 22%
• 2020

  A review of recently described genetic alterations in central nervous system tumors

  Lucas, C. H. G., Solomon, D. A. & Perry, A., Feb 2020, In: Human pathology. 96, p. 56-66 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Central Nervous System Neoplasms 100%
  • Glioma 49%
  • Ependymoma 34%
  • Medulloblastoma 32%
  • Germ Cell and Embryonal Neoplasms 31%

• Clinicopathological features and outcomes of parenchymal rejection in liver transplant biopsies

  Fels Elliott, D. R., Tavakol, M., Lucas, C. H., Sheahon, K., Kakar, S., Hameed, B., Ferrell, L. D. & Gill, R. M., May 1 2020, In: Histopathology. 76, 6, p. 822-831 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Liver Transplantation 100%
  • Biopsy 66%
  • Liver 33%
  • Venules 26%
  • Enzymes 24%

• Coccidioidomycosis Presenting with Fever and Back Pain

  Pillsbury, M. K. M., Rubio, L. A., Lucas, C. H. G. & Babik, J. M., Jun 1 2020, In: Journal of general internal medicine. 35, 6, p. 1887-1888 2 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Comprehensive analysis of diverse low-grade neuroepithelial tumors with FGFR1 alterations reveals a distinct molecular signature of rosette-forming glioneuronal tumor

  Lucas, C. H. G., Gupta, R., Doo, P., Lee, J. C., Cadwell, C. R., Ramani, B., Hofmann, J. W., Sloan, E. A., Kleinschmidt-Demasters, B. K., Lee, H. S., Wood, M. D., Grafe, M., Born, D., Vogel, H., Salamat, S., Puccetti, D., Scharnhorst, D., Samuel, D., Cooney, T., Cham, E., & 31 othersJin, L. W., Khatib, Z., Maher, O., Chamyan, G., Brathwaite, C., Bannykh, S., Mueller, S., Kline, C. N., Banerjee, A., Reddy, A., Taylor, J. W., Clarke, J. L., Oberheim Bush, N. A., Butowski, N., Gupta, N., Auguste, K. I., Sun, P. P., Roland, J. L., Raffel, C., Aghi, M. K., Theodosopoulos, P., Chang, E., Hervey-Jumper, S., Phillips, J. J., Pekmezci, M., Bollen, A. W., Tihan, T., Chang, S., Berger, M. S., Perry, A. & Solomon, D. A., Aug 28 2020, In: Acta Neuropathologica Communications. 8, 1, 151.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Neuroepithelial Neoplasms 100%
  • Astrocytoma 33%
  • Neurocytoma 24%
  • Missense Mutation 23%
  • Neoplasms 22%

• Histopathologic findings in malignant peripheral nerve sheath tumor predict response to radiotherapy and overall survival

  Lucas, C. H. G., Vasudevan, H. N., Chen, W. C., Magill, S. T., Braunstein, S. E., Jacques, L., Dahiya, S., Rodriguez, F. J., Horvai, A. E., Perry, A., Pekmezci, M. & Raleigh, D. R., Jan 1 2020, In: Neuro-Oncology Advances. 2, 1, vdaa131.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Neurofibrosarcoma 100%
  • Radiotherapy 51%
  • San Francisco 46%
  • Survival 41%
  • Medical Records 30%

• Meningioma metastases: Incidence and proposed screening paradigm

  Dalle, C. L., Magill, S. T., Yen, A. J., Shahin, M. N., Lee, D. S., Lucas, C. H. G., Chen, W. C., Viner, J. A., Aghi, M. K., Theodosopoulos, P. V., Raleigh, D. R., Villanueva-Meyer, J. E. & McDermott, M. W., May 2020, In: Journal of neurosurgery. 132, 5, p. 1447-1455 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Meningioma 100%
  • Neoplasm Metastasis 56%
  • Incidence 44%
  • Biopsy 11%
  • Recurrence 11%

• Myxoid glioneuronal tumor, PDGFRA p.K385-mutant: clinical, radiologic, and histopathologic features

  Lucas, C. H. G., Villanueva-Meyer, J. E., Whipple, N., Oberheim Bush, N. A., Cooney, T., Chang, S., McDermott, M., Berger, M., Cham, E., Sun, P. P., Putnam, A., Zhou, H., Bollo, R., Cheshier, S., Poppe, M. M., Fung, K. M., Sung, S., Glenn, C., Fan, X., Bannykh, S., & 15 othersHu, J., Danielpour, M., Li, R., Alva, E., Johnston, J., Van Ziffle, J., Onodera, C., Devine, P., Grenert, J. P., Lee, J. C., Pekmezci, M., Tihan, T., Bollen, A. W., Perry, A. & Solomon, D. A., May 1 2020, In: Brain Pathology. 30, 3, p. 479-494 16 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Septum Pellucidum 100%
  • Neoplasms 55%
  • Corpus Callosum 47%
  • Hydrocephalus 44%
  • White Matter 38%
• 2019

  Educational Case: Mitochondrial Myopathy

  Lucas, C. H. G. & Margeta, M., 2019, In: Academic Pathology. 6

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Mitochondrial Myopathies 100%
  • Pathology 42%
  • Learning 24%
  • Medical Education 18%
  • Teaching 14%

• Preoperative MR imaging to differentiate chordoid meningiomas from other meningioma histologic subtypes

  Baal, J. D., Chen, W. C., Solomon, D. A., Pai, J. S., Lucas, C. H., Hara, J. H., Oberheim Bush, N. A., McDermott, M. W., Raleigh, D. R. & Villanueva-Meyer, J. E., 2019, In: American Journal of Neuroradiology. 40, 3, p. 433-439 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Notochord 100%
  • Meningioma 79%
  • Histology 36%
  • Brain Neoplasms 3%

• Surgical outcomes after reoperation for recurrent skull base meningiomas

  Magill, S. T., Lee, D. S., Yen, A. J., Lucas, C. H. G., Raleigh, D. R., Aghi, M. K., Theodosopoulos, P. V. & McDermott, M. W., Mar 2019, In: Journal of neurosurgery. 130, 3, p. 876-883 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Skull Base 100%
  • Meningioma 99%
  • Reoperation 84%
  • Cranial Nerves 14%
  • Kaplan-Meier Estimate 12%
• 2018

  Surgical Outcomes, Complications, and Management Strategies for Foramen Magnum Meningiomas

  Magill, S. T., Shahin, M. N., Lucas, C. H. G., Yen, A. J., Lee, D. S., Raleigh, D. R., Aghi, M. K., Theodosopoulos, P. V. & McDermott, M. W., May 28 2018, In: Journal of Neurological Surgery, Part B: Skull Base. 80, 1, p. 1-9 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Foramen Magnum 100%
  • Meningioma 77%
  • Odds Ratio 36%
  • Vertebral Artery 33%
  • Tumor Burden 27%

• Tuberculum sellae meningiomas: Grading scale to assess surgical outcomes using the transcranial versus transsphenoidal approach

  Magill, S. T., Morshed, R. A., Lucas, C. H. G., Aghi, M. K., Theodosopoulos, P. V., Berger, M. S., de Divitiis, O., Solari, D., Cappabianca, P., Cavallo, L. M. & McDermott, M. W., Apr 1 2018, In: Neurosurgical focus. 44, 4, E9.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Meningioma 100%
  • Ocular Vision 44%
  • Neoplasms 29%
  • Recurrence 15%
  • Neoplasm Grading 14%
• 2015

  Cortical neurons are a prominent source of the proinflammatory cytokine osteopontin in HIV-associated neurocognitive disorders

  Silva, K., Hope-Lucas, C., White, T., Hairston, T. K., Rameau, T. & Brown, A., Apr 1 2015, In: Journal of neurovirology. 21, 2, p. 174-185 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Neurocognitive Disorders 100%
  • Osteopontin 86%
  • HIV 50%
  • Cytokines 45%
  • Neurons 44%
  11 Scopus citations
• 2014

  Altered subcellular localization of the NeuN/Rbfox3 RNA splicing factor in HIV-associated neurocognitive disorders (HAND)

  Lucas, C. H., Calvez, M., Babu, R. & Brown, A., Jan 13 2014, In: Neuroscience Letters. 558, p. 97-102 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Neurocognitive Disorders 100%
  • RNA Splicing Factors 96%
  • HIV 50%
  • Neurons 44%
  • Cytoplasm 39%
  16 Scopus citations