Bill Mathews

Research output

Research output per year 1994 1994 1995 1996 1998 1999 2002 2006 2008 2019 2023

• 80 Article
• 3 Review article
• 1 Chapter
• 1 Comment/debate
• 1 More
  • 1 Letter

Research output per year

Research output per year

Search results

• 2023

  First-in-human imaging using [¹¹C]MDTC: a radiotracer targeting the cannabinoid receptor type 2

  Du, Y., Coughlin, J. M., Brosnan, M. K., Chen, A., Shinehouse, L. K., Abdallah, R., Lodge, M. A., Mathews, W. B., Liu, C., Wu, Y., Minn, I., Finley, P., Hall, A. W., Lesniak, W. G., Dannals, R. F., Horti, A. G. & Pomper, M. G., Jul 2023, In: European Journal of Nuclear Medicine and Molecular Imaging. 50, 8, p. 2386-2393 8 p.

  Research output: Contribution to journal › Article › peer-review

  • monodansylthiacadaverine 100%
  • Cannabinoid Receptors 58%
  • Positron-Emission Tomography 31%
  • Brain 16%
  • Microglia 4%

• Imaging Brain Injury in Former National Football League Players

  Rubin, L. H., Du, Y., Sweeney, S. E., O’Toole, R., Thomas, C. L., Zandi, A. G., Shinehouse, L. K., Brosnan, M. K., Nam, H., Burke, M. E., Bureau, S. C., Kilgore, J. J., Yoon, M., Soule, A. R., Lesniak, W. G., Minn, I., Rowe, S. P., Holt, D. P., Hall, A. W., Mathews, W. B., & 6 othersSmith, G. S., Nowinski, C. J., Kassiou, M., Dannals, R. F., Pomper, M. G. & Coughlin, J. M., 2023, (Accepted/In press) In: JAMA Network Open. p. E2340580

  Research output: Contribution to journal › Article › peer-review

  • Football 100%
  • N,N-diethyl-2-(2-(4-methoxyphenyl)-5,7-dimethyl-pyrazolo(1,5-a)pyrimidin-3-yl)-acetamide 98%
  • Brain Injuries 82%
  • Athletes 60%
  • Sports 58%
• 2021

  ¹⁸F-labeled radiotracers for in vivo imaging of DREADD with positron emission tomography

  Hu, F., Morris, P. J., Bonaventura, J., Fan, H., Mathews, W. B., Holt, D. P., Lam, S., Boehm, M., Dannals, R. F., Pomper, M. G., Michaelides, M. & Horti, A. G., Mar 5 2021, In: European Journal of Medicinal Chemistry. 213, 113047.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Designer Drugs 100%
  • Designer Drug 98%
  • Positron 77%
  • Positron-Emission Tomography 61%
  • Clozapine 38%
  2 Scopus citations

• Molecular imaging of beta-amyloid deposition in late-life depression

  Smith, G. S., Kuwabara, H., Nandi, A., Gould, N. F., Nassery, N., Savonenko, A., Joo, J. H., Kraut, M., Brasic, J., Holt, D. P., Hall, A. W., Mathews, W. B., Dannals, R. F., Avramopoulos, D. & Workman, C. I., May 2021, In: Neurobiology of aging. 101, p. 85-93 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Molecular Imaging 100%
  • Amyloid 80%
  • Spatial Memory 20%
  • Sertraline 12%
  • Citalopram 11%

• Molecular imaging of the serotonin transporter availability and occupancy by antidepressant treatment in late-life depression

  Smith, G. S., Kuwabara, H., Gould, N. F., Nassery, N., Savonenko, A., Joo, J. H., Bigos, K. L., Kraut, M., Brasic, J., Holt, D. P., Hall, A. W., Mathews, W. B., Dannals, R. F., Nandi, A. & Workman, C. I., Aug 15 2021, In: Neuropharmacology. 194, 108447.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Serotonin Plasma Membrane Transport Proteins 100%
  • Molecular Imaging 94%
  • Antidepressive Agents 72%
  • Gray Matter 18%
  • Therapeutics 13%
• 2020

  Correction to: Osteopontin/secreted phosphoprotein-1 behaves as a molecular brake regulating the neuroinflammatory response to chronic viral infection (Journal of Neuroinflammation, (2020), 17, 1, (273), 10.1186/s12974-020-01949-4)

  Mahmud, F. J., Du, Y., Greif, E., Boucher, T., Dannals, R. F., Mathews, W. B., Pomper, M. G., Sysa-Shah, P., Metcalf Pate, K. A., Lyons, C., Carlson, B., Chacona, M. & Brown, A. M., Dec 2020, In: Journal of Neuroinflammation. 17, 1, 344.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  • Osteopontin 100%
  • Publications 69%
  • Virus Diseases 62%

• Dynamic imaging in patients with tuberculosis reveals heterogeneous drug exposures in pulmonary lesions

  Ordonez, A. A., Wang, H., Magombedze, G., Ruiz-Bedoya, C. A., Srivastava, S., Chen, A., Tucker, E. W., Urbanowski, M. E., Pieterse, L., Fabian Cardozo, E., Lodge, M. A., Shah, M. R., Holt, D. P., Mathews, W. B., Dannals, R. F., Gobburu, J. V. S., Peloquin, C. A., Rowe, S. P., Gumbo, T., Ivaturi, V. D., & 1 othersJain, S. K., Apr 1 2020, In: Nature medicine. 26, 4, p. 529-534 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Rifampin 100%
  • Tuberculosis 77%
  • Antimicrobial Agent 66%
  • Positron 55%
  • Lung 50%
  21 Scopus citations

• Osteopontin/secreted phosphoprotein-1 behaves as a molecular brake regulating the neuroinflammatory response to chronic viral infection

  Mahmud, F. J., Du, Y., Greif, E., Boucher, T., Dannals, R. F., Mathews, W. B., Pomper, M. G., Sysa-Shah, P., Metcalf Pate, K. A., Lyons, C., Carlson, B., Chacona, M. & Brown, A. M., Sep 17 2020, In: Journal of Neuroinflammation. 17, 1, 273.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Osteopontin 100%
  • Virus Diseases 62%
  • Proteins 31%
  • Brain 29%
  • HIV 24%
  2 Scopus citations
• 2019

  Effect of STN DBS on vesicular monoamine transporter 2 and glucose metabolism in Parkinson's disease

  Smith, G. S., Mills, K. A., Pontone, G. M., Anderson, W. S., Perepezko, K. M., Brasic, J., Zhou, Y., Brandt, J., Butson, C. R., Holt, D. P., Mathews, W. B., Dannals, R. F., Wong, D. F. & Mari, Z., Jul 2019, In: Parkinsonism and Related Disorders. 64, p. 235-241 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Vesicular Monoamine Transport Proteins 100%
  • Thalamic Nuclei 85%
  • Deep Brain Stimulation 77%
  • Corpus Striatum 64%
  • Parkinson Disease 55%
  3 Scopus citations

• PET/CT Imaging of Cardiac Angiotensin II Type 1 Receptors in Nonobstructive Hypertrophic Cardiomyopathy

  Valenta, I., Szabo, Z., Mathews, W. B., Abraham, T. P., Abraham, R. & Schindler, T., Sep 2019, In: JACC: Cardiovascular Imaging. 12, 9, p. 1895-1896 2 p.

  Research output: Contribution to journal › Letter › peer-review
  4 Scopus citations

• PET imaging of microglia by targeting macrophage colony-stimulating factor 1 receptor (CSF1R)

  Horti, A. G., Naik, R., Foss, C. A., Minn, I., Misheneva, V., Du, Y., Wang, Y., Mathews, W. B., Wu, Y., Hall, A., LaCourse, C., Ahn, H. H., Nam, H., Lesniak, W. G., Valentine, H., Pletnikova, O., Troncoso, J. C., Smith, M. D., Calabresi, P. A., Savonenko, A. V., & 3 othersDannals, R. F., Pletnikov, M. V. & Pomper, M. G., Jan 29 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 5, p. 1686-1691 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Macrophage Colony-Stimulating Factor Receptors 100%
  • Macrophage Colony-Stimulating Factor 80%
  • Microglia 67%
  • Alzheimer Disease 51%
  • Demyelinating Diseases 46%
  44 Scopus citations

• Radiosynthesis and validation of [5-cyano-N-(4-(4-[¹¹C]methylpiperazin-1-yl)-2-(piperidin-1-yl)phenyl) furan-2-carboxamide] ([¹¹C]CPPC), a PET radiotracer for imaging CSF1R, a microglia-specific marker

  Mathews, W. B., Wu, Y., Horti, A. G., Naik, R., Hall, A. W., Holt, D. P. & Dannals, R. F., Nov 1 2019, In: Journal of Labelled Compounds and Radiopharmaceuticals. 62, 13, p. 903-908 6 p.

  Research output: Contribution to journal › Article › peer-review

  • furan 100%
  • Pyrogens 95%
  • Microglia 66%
  • Quality Control 63%
  • Marker 56%
  1 Scopus citations
• 2018

  Feasibility Evaluation of Myocardial Cannabinoid Type 1 Receptor Imaging in Obesity: A Translational Approach

  Valenta, I., Varga, Z. V., Valentine, H., Cinar, R., Horti, A., Mathews, W. B., Dannals, R. F., Steele, K., Kunos, G., Wahl, R. L., Pomper, M. G., Wong, D. F., Pacher, P. & Schindler, T. H., Feb 2018, In: JACC: Cardiovascular Imaging. 11, 2P2, p. 320-332 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Cannabinoid Receptors 100%
  • Cannabinoids 92%
  • Obesity 55%
  • Positron Emission Tomography Computed Tomography 39%
  • Obese Mice 26%
  18 Scopus citations

• Imaging glial activation in patients with post-treatment Lyme disease symptoms: A pilot study using [ ¹¹ C]DPA-713 PET

  Coughlin, J. M., Yang, T., Rebman, A. W., Bechtold, K. T., Du, Y., Mathews, W. B., Lesniak, W. G., Mihm, E. A., Frey, S. M., Marshall, E. S., Rosenthal, H. B., Reekie, T. A., Kassiou, M., Dannals, R. F., Soloski, M. J., Aucott, J. N. & Pomper, M. G., Dec 19 2018, In: Journal of Neuroinflammation. 15, 1, 346.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • N,N-diethyl-2-(2-(4-methoxyphenyl)-5,7-dimethyl-pyrazolo(1,5-a)pyrimidin-3-yl)-acetamide 100%
  • Post-Lyme Disease Syndrome 84%
  • Neuroglia 42%
  • Microglia 32%
  • Brain 23%
  9 Scopus citations

• Noninvasive ¹¹C-rifampin positron emission tomography reveals drug biodistribution in tuberculous meningitis

  Tucker, E. W., Guglieri-Lopez, B., Ordonez, A. A., Ritchie, B., Klunk, M. H., Sharma, R., Chang, Y. S., Sanchez-Bautista, J., Frey, S., Lodge, M. A., Rowe, S. P., Holt, D. P., Gobburu, J. V. S., Peloquin, C. A., Mathews, W. B., Dannals, R. F., Pardo, C. A., Kannan, S., Ivaturi, V. D. & Jain, S. K., Dec 5 2018, In: Science translational medicine. 10, 470, aau0965.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Meningeal Tuberculosis 100%
  • Rifampin 79%
  • Positron-Emission Tomography 69%
  • Pharmaceutical Preparations 30%
  • Brain 24%
  29 Scopus citations
• 2017

  Chemogenetics revealed: DREADD occupancy and activation via converted clozapine

  Gomez, J. L., Bonaventura, J., Lesniak, W., Mathews, W. B., Sysa-Shah, P., Rodriguez, L. A., Ellis, R. J., Richie, C. T., Harvey, B. K., Dannals, R. F., Pomper, M. G., Bonci, A. & Michaelides, M., Aug 4 2017, In: Science. 357, 6350, p. 503-507 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • clozapine N-oxide 100%
  • Designer Drugs 85%
  • Metabolic Activation 68%
  • Clozapine 66%
  • Injections 19%
  409 Scopus citations

• Development of a radioligand for imaging V_1a vasopressin receptors with PET

  Naik, R., Valentine, H., Hall, A., Mathews, W. B., Harris, J. C., Carter, C. S., Dannals, R. F., Wong, D. F. & Horti, A. G., Oct 20 2017, In: European Journal of Medicinal Chemistry. 139, p. 644-656 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Vasopressin Receptors 100%
  • Anaesthetic 94%
  • Positron 89%
  • Radioligand 85%
  • Positron-Emission Tomography 71%
  1 Scopus citations

• Identification of Three Novel Radiotracers for Imaging Aggregated Tau in Alzheimer's Disease with Positron Emission Tomography

  Gobbi, L. C., Knust, H., Körner, M., Honer, M., Czech, C., Belli, S., Muri, D., Edelmann, M. R., Hartung, T., Erbsmehl, I., Grall-Ulsemer, S., Koblet, A., Rueher, M., Steiner, S., Ravert, H. T., Mathews, W. B., Holt, D. P., Kuwabara, H., Valentine, H., Dannals, R. F., & 2 othersWong, D. F. & Borroni, E., Sep 14 2017, In: Journal of medicinal chemistry. 60, 17, p. 7350-7370 21 p.

  Research output: Contribution to journal › Article › peer-review

  • Positron 100%
  • Beta-Amyloid 96%
  • Amines 90%
  • Positron-Emission Tomography 79%
  • Biological Marker 77%
  40 Scopus citations
• 2015

  Quantitative Multi-modal Brain Autoradiography of Glutamatergic, Dopaminergic, Cannabinoid, and Nicotinic Receptors in Mutant Disrupted-In-Schizophrenia-1 (DISC1) Mice

  Kim, J., Horti, A. G., Mathews, W. B., Pogorelov, V., Valentine, H., Brasic, J. R., Holt, D. P., Ravert, H. T., Dannals, R. F., Zhou, L., Jedynak, B., Kamiya, A., Pletnikov, M. V. & Wong, D. F., Jun 1 2015, In: Molecular Imaging and Biology. 17, 3, p. 355-363 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Cannabinoid Receptors 100%
  • Nicotinic Receptors 87%
  • Autoradiography 83%
  • Schizophrenia 64%
  • Nucleus Accumbens 43%
  7 Scopus citations
• 2014

  Dose-dependent, saturable occupancy of the metabotropic glutamate subtype 5 receptor by fenobam as measured with [¹¹C]ABP688 PET imaging

  Mathews, W. B., Kuwabara, H., Stansfield, K., Valentine, H., Alexander, M., Kumar, A., Hilton, J., Dannals, R. F., Wong, D. F. & Gasparini, F., Dec 1 2014, In: Synapse. 68, 12, p. 565-573 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • fenobam 100%
  • 3-(6-methylpyridin-2-ylethynyl)cyclohex-2-enone-O-methyloxime 97%
  • Metabotropic Glutamate 5 Receptor 75%
  • Primates 13%
  • Fragile X Syndrome 9%
  19 Scopus citations
• 2013

  Modeling of the renal kinetics of the at1 receptor specific PET radioligand [¹¹C]KR31173

  Gulaldi, N. C. M., Xia, J., Feng, T., Hong, K., Mathews, W. B., Ruben, D., Kamel, I. R., Tsui, B. M. W. & Szabo, Z., 2013, In: BioMed research international. 2013, 835859.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • 2-butyl-5-methoxymethyl-6-(1-oxopyridin-2-yl)-3-((2'-(1H-tetrazol-5-yl)bipohenyl-4-yl)methyl)-3H-imidazo(4,5-b)pyridine 100%
  • Radioligand 48%
  • Autoradiography 45%
  • Reperfusion 37%
  • Ischemia 32%
  6 Scopus citations

• Targeting of endothelin receptors in the healthy and infarcted rat heart using the PET tracer ¹⁸F-FBzBMS

  Higuchi, T., Rischpler, C., Fukushima, K., Isoda, T., Xia, J., Javadi, M. S., Szabo, Z., Dannals, R. F., Mathews, W. B. & Bengel, F. M., Feb 2013, In: Journal of Nuclear Medicine. 54, 2, p. 277-282 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • N-((2'-(((4,5-dimethyl-3-isoxazolyl)amino)sulfonyl)-4-(2-oxazolyl)(1,1'-biphenyl)-2-yl)methyl)-N,4-fluorobenzamide 100%
  • Endothelin Receptors 55%
  • Endothelin A Receptors 54%
  • Heart 25%
  • Myocardial Infarction 19%
  12 Scopus citations
• 2012

  Molecular hybrid positron emission tomography/computed tomography imaging of cardiac angiotensin ii type 1 receptors

  Fukushima, K., Bravo, P. E., Higuchi, T., Schuleri, K. H., Lin, X., Abraham, M. R., Xia, J., Mathews, W. B., Dannals, R. F., Lardo, A. C., Szabo, Z. & Bengel, F. M., Dec 18 2012, In: Journal of the American College of Cardiology. 60, 24, p. 2527-2534 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Angiotensin Type 1 Receptor 100%
  • Positron Emission Tomography Computed Tomography 88%
  • Infarction 30%
  • Swine 28%
  • 2-butyl-5-methoxymethyl-6-(1-oxopyridin-2-yl)-3-((2'-(1H-tetrazol-5-yl)bipohenyl-4-yl)methyl)-3H-imidazo(4,5-b)pyridine 20%
  50 Scopus citations
• 2011

  Molecular imaging of the kidneys

  Szabo, Z., Alachkar, N., Xia, J., Mathews, W. B. & Rabb, H., Jan 2011, In: Seminars in Nuclear Medicine. 41, 1, p. 20-28 9 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Molecular Imaging 100%
  • Kidney Neoplasms 54%
  • Kidney 45%
  • Radiopharmaceuticals 29%
  • Renal Circulation 28%
  16 Scopus citations
• 2010

  Radioligands for the angiotensin II subtype 1 (AT1) receptor

  Mathews, W. B. & Szabo, Z., 2010, In: Current topics in medicinal chemistry. 10, 16, p. 1585-1599 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Angiotensin II 100%
  • Radioligand 88%
  • Ligands 55%
  • Hypertension 51%
  • Angiotensin-Converting Enzyme Inhibitor 36%
  2 Scopus citations

• Radionuclide imaging of angiotensin II type 1 receptor upregulation after myocardial ischemia-reperfusion injury

  Higuchi, T., Fukushima, K., Xia, J., Mathews, W. B., Lautamäki, R., Bravo, P. E., Javadi, M. S., Dannals, R. F., Szabo, Z. & Bengel, F. M., Dec 1 2010, In: Journal of Nuclear Medicine. 51, 12, p. 1956-1961 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • 2-butyl-5-methoxymethyl-6-(1-oxopyridin-2-yl)-3-((2'-(1H-tetrazol-5-yl)bipohenyl-4-yl)methyl)-3H-imidazo(4,5-b)pyridine 100%
  • KR 31080 98%
  • Myocardial Reperfusion Injury 92%
  • Angiotensin Type 1 Receptor 88%
  • Valsartan 78%
  29 Scopus citations
• 2008

  Chronic ACE inhibitor treatment increases angiotensin type 1 receptor binding in vivo in the dog kidney

  Zober, T. G., Fabucci, M. E., Zheng, W., Brown, P. R., Seckin, E., Mathews, W. B., Sandberg, K. & Szabo, Z., Jun 2008, In: European Journal of Nuclear Medicine and Molecular Imaging. 35, 6, p. 1109-1116 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Angiotensin Type 1 Receptor 100%
  • Angiotensin-Converting Enzyme Inhibitors 80%
  • Dogs 58%
  • Kidney 43%
  • Angiotensin II 33%
  6 Scopus citations

• Positron emission tomographic studies of brain dopamine and serotonin transporters in abstinent (±)3,4-methylenedioxymethamphetamine ("ecstasy") users: Relationship to cognitive performance

  McCann, U. D., Szabo, Z., Vranesic, M., Palermo, M., Mathews, W. B., Ravert, H. T., Dannals, R. F. & Ricaurte, G. A., Oct 2008, In: Psychopharmacology. 200, 3, p. 439-450 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • N-Methyl-3,4-methylenedioxyamphetamine 100%
  • Serotonin Plasma Membrane Transport Proteins 92%
  • Dopamine Plasma Membrane Transport Proteins 91%
  • Electrons 59%
  • Brain 36%
  116 Scopus citations

• Positron-emission tomography imaging of the angiotensin II subtype 1 receptor in swine renal artery stenosis

  Xia, J., Seckin, E., Xiang, Y., Vranesic, M., Mathews, W. B., Hong, K., Bluemke, D. A., Lerman, L. O. & Szabo, Z., Feb 2008, In: Hypertension. 51, 2 PART 2, p. 466-473 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Renal Artery Obstruction 100%
  • Angiotensin II 76%
  • Positron-Emission Tomography 73%
  • Swine 62%
  • Lisinopril 55%
  19 Scopus citations

• Radiopharmaceuticals for Renal Positron Emission Tomography Imaging

  Szabo, Z., Xia, J. & Mathews, W. B., Jan 2008, In: Seminars in Nuclear Medicine. 38, 1, p. 20-31 12 p.

  Research output: Contribution to journal › Review article › peer-review

  • Radiopharmaceuticals 100%
  • Positron-Emission Tomography 77%
  • Kidney 44%
  • Endothelin Receptors 11%
  • Angiotensin Receptors 10%
  7 Scopus citations

• Synthesis and in vivo evaluation of novel PET radioligands for imaging the endothelin-A receptor

  Mathews, W. B., Murugesan, N., Xia, J., Scheffel, U., Hilton, J., Ravert, H. T., Dannals, R. F. & Szabo, Z., Sep 1 2008, In: Journal of Nuclear Medicine. 49, 9, p. 1529-1536 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • N-((2'-(((4,5-dimethyl-3-isoxazolyl)amino)sulfonyl)-4-(2-oxazolyl)(1,1'-biphenyl)-2-yl)methyl)-N,4-fluorobenzamide 100%
  • N-((2'-(((4,5-dimethyl-3-isoxazolyl)amino)sulfonyl)-4-(2-oxazolyl)(1,1'-biphenyl)-2-yl)methyl)-N,3,3-trimethylbutanamide 79%
  • Endothelin A Receptors 54%
  • diphenyl 24%
  • Heart 17%
  9 Scopus citations
• 2006

  Future direction of renal positron emission tomography

  Szabo, Z., Xia, J., Mathews, W. B. & Brown, P. R., Jan 2006, In: Seminars in Nuclear Medicine. 36, 1, p. 36-50 15 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Positron-Emission Tomography 100%
  • Direction compound 77%
  • Kidney 57%
  • Renal Circulation 37%
  • Rubidium-82 37%
  41 Scopus citations

• PET imaging of the AT₁ receptor with [¹¹C]KR31173

  Zober, T. G., Mathews, W. B., Seckin, E., Yoo, S. E., Hilton, J., Xia, J., Sandberg, K., Ravert, H. T., Dannals, R. F. & Szabo, Z., Jan 2006, In: Nuclear Medicine and Biology. 33, 1, p. 5-13 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • 2-butyl-5-methoxymethyl-6-(1-oxopyridin-2-yl)-3-((2'-(1H-tetrazol-5-yl)bipohenyl-4-yl)methyl)-3H-imidazo(4,5-b)pyridine 100%
  • Papio 52%
  • L 159884 42%
  • Kidney 23%
  • Dogs 18%
  24 Scopus citations

• Positron emission tomography imaging of the kidneys

  Szabo, Z. & Mathews, W. B., Jan 1 2006, Functional Imaging in Nephro-Urology. CRC Press, p. 197-210 14 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • neurology 100%
  • quantification 84%
  • medicine 54%

• Synthesis and in vivo evaluation of a PET radioligand for imaging the endothelin-A receptor

  Mathews, W. B., Zober, T. G., Ravert, H. T., Scheffel, U., Hilton, J., Sleep, D., Dannals, R. F. & Szabo, Z., Jan 2006, In: Nuclear Medicine and Biology. 33, 1, p. 15-19 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Atrasentan 100%
  • Endothelin A Receptors 80%
  • Lung 31%
  • Myocardium 24%
  • Heart 19%
  9 Scopus citations

• Synthesis of 2-[¹⁸F]fluoroadenosine (2-[¹⁸F]FAD) as potential radiotracer for studying malignancies by PET

  Horti, A. G., Ravert, H. T., Mathews, W. B., Abraham, E. H., Wahl, R. L. & Dannals, R. F., Aug 2006, In: Journal of Labelled Compounds and Radiopharmaceuticals. 49, 9, p. 811-815 5 p.

  Research output: Contribution to journal › Article › peer-review

  • 2-iodoadenosine 100%
  • 2-fluoroadenosine 82%
  • 2-Fluoroadenosine 74%
  • Radiochemical Yield 46%
  • Radioligand 43%
  6 Scopus citations

• Synthesis of a mGluR5 antagonist using [¹¹C]cOpper(I) cyanide

  Mathews, W. B., Monn, J. A., Ravert, H. T., Holt, D. P., Schoepp, D. D. & Dannals, R. F., Aug 2006, In: Journal of Labelled Compounds and Radiopharmaceuticals. 49, 9, p. 829-834 6 p.

  Research output: Contribution to journal › Article › peer-review

  • pyridine-3-carbonitrile 100%
  • Metabotropic Glutamate 5 Receptor 67%
  • Halogens 63%
  • Cyanides 58%
  • Radiochemical Yield 53%
  17 Scopus citations
• 2005

  Quantitative PET studies of the serotonin transporter in MDMA users and controls using [¹¹C]McN5652 and [¹¹C]DASB

  McCann, U. D., Szabo, Z., Seckin, E., Rosenblatt, P., Mathews, W. B., Ravert, H. T., Dannals, R. F. & Ricaurte, G. A., Sep 2005, In: Neuropsychopharmacology. 30, 9, p. 1741-1750 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • 3-amino-4-(2-dimethylaminomethylphenylsulfanyl)benzonitrile 100%
  • N-Methyl-3,4-methylenedioxyamphetamine 74%
  • Serotonin Plasma Membrane Transport Proteins 69%
  • Positron-Emission Tomography 51%
  • Serotonin 17%
  171 Scopus citations

• Synthesis and biodistribution of [¹¹C]adenosine 5′-monophosphate ([¹¹C]AMP)

  Mathews, W. B., Nakamoto, Y., Abraham, E. H., Scheffel, U., Hilton, J., Ravert, H. T., Tatsumi, M., Rauseo, P. A., Traughber, B. J., Salikhova, A. Y., Dannals, R. F. & Wahl, R. L., May 2005, In: Molecular Imaging and Biology. 7, 3, p. 203-208 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Adenosine Monophosphate 100%
  • Dipyridamole 55%
  • Positron-Emission Tomography 20%
  • In Vivo Dosimetry 18%
  • Lung 18%
  12 Scopus citations

• Synthesis and biodistribution of ¹¹C-GW7845, a positron-emitting agonist for peroxisome proliferator-activated receptor-γ

  Mathews, W. B., Foss, C. A., Stoermer, D., Ravert, H. T., Dannals, R. F., Henke, B. R. & Pomper, M. G., Oct 1 2005, In: Journal of Nuclear Medicine. 46, 10, p. 1719-1726 8 p.

  Research output: Contribution to journal › Article › peer-review

  • GW 7845 100%
  • Peroxisome Proliferator-Activated Receptors 57%
  • methyl 2-(1-carboxy-2-(4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)phenyl)ethylamino)benzoate 39%
  • Electrons 38%
  • Tail 30%
  8 Scopus citations
• 2004

  A novel radioligand for imaging the AT₁ angiotensin receptor with PET

  Mathews, W. B., Yoo, S. E., Lee, S. H., Scheffel, U., Rauseo, P. A., Zober, T. G., Gocco, G., Sandberg, K., Ravert, H. T., Dannals, R. F. & Szabo, Z., Jul 2004, In: Nuclear Medicine and Biology. 31, 5, p. 571-574 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Angiotensin Type 1 Receptor 100%
  • 2-butyl-5-methoxymethyl-6-(1-oxopyridin-2-yl)-3-((2'-(1H-tetrazol-5-yl)bipohenyl-4-yl)methyl)-3H-imidazo(4,5-b)pyridine 94%
  • MK 996 92%
  • Adrenal Glands 86%
  • imidazo(4,5-b)pyridine 81%
  24 Scopus citations

• In vivo investigation of estrogen regulation of adrenal and renal angiotensin (AT₁) receptor expression by PET

  Owonikoko, T. K., Fabucci, M. E., Brown, P. R., Nisar, N., Hilton, J., Mathews, W. B., Ravert, H. T., Rauseo, P., Sandberg, K., Dannals, R. F. & Szabo, Z., Jan 1 2004, In: Journal of Nuclear Medicine. 45, 1, p. 94-100 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Angiotensin Type 1 Receptor 100%
  • Angiotensins 93%
  • Estrogens 66%
  • Kidney 43%
  • Renin-Angiotensin System 18%
  40 Scopus citations

• Positron emission tomography imaging of the serotonin transporter in subjects with a history of alcoholism

  Szabo, Z., Owonikoko, T., Peyrot, M., Varga, J., Mathews, W. B., Ravert, H. T., Dannals, R. F. & Wand, G., Apr 1 2004, In: Biological psychiatry. 55, 7, p. 766-771 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Serotonin Plasma Membrane Transport Proteins 100%
  • Positron-Emission Tomography 74%
  • Alcoholism 73%
  • Alcoholics 53%
  • Brain 39%
  46 Scopus citations
• 2003

  Positron emission tomography of striatal serotonin transporters in Parkinson disease

  Kerenyi, L., Ricaurte, G. A., Schretlen, D. J., McCann, U., Varga, J., Mathews, W. B., Ravert, H. T., Dannals, R. F., Hilton, J., Wong, D. F. & Szabo, Z., Sep 1 2003, In: Archives of neurology. 60, 9, p. 1223-1229 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Parkinson's Disease 100%
  • Positron Emission Tomography 89%
  • Serotonin Plasma Membrane Transport Proteins 70%
  • Corpus Striatum 55%
  • Positron-Emission Tomography 52%
  114 Scopus citations
• 2002

  [¹¹C]-GR89696, a potent kappa opiate receptor radioligand; in vivo binding of the R and S enantiomers

  Ravert, H. T., Scheffel, U., Mathews, W. B., Musachio, J. L. & Dannals, R. F., 2002, In: Nuclear Medicine and Biology. 29, 1, p. 47-53 7 p.

  Research output: Contribution to journal › Article › peer-review

  • GR 89696 100%
  • kappa Opioid Receptor 60%
  • methyl chloroformate 53%
  • Opioid Receptors 52%
  • Olfactory Tubercle 33%
  29 Scopus citations

• Carbon-11 labeled radioligands for imaging brain cannabinoid receptors

  Mathews, W. B., Scheffel, U., Rauseo, P. A., Ravert, H. T., Frank, R. A., Ellames, G. J., Herbert, J. M., Barth, F., Rinaldi-Carmona, M. & Dannals, R. F., Aug 2002, In: Nuclear Medicine and Biology. 29, 6, p. 671-677 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Carbon-11 100%
  • Cannabinoid Receptors 80%
  • Neuroimaging 57%
  • methyl iodide 55%
  • Rimonabant 44%
  23 Scopus citations

• Comparison of (+)-¹¹C-McN5652 and ¹¹C-DASB as serotonin transporter radioligands under various experimental conditions

  Szabo, Z., McCann, U. D., Wilson, A. A., Scheffel, U., Owonikoko, T., Mathews, W. B., Ravert, H. T., Hilton, J., Dannals, R. F. & Ricaurte, G. A., 2002, In: Journal of Nuclear Medicine. 43, 5, p. 678-692 15 p.

  Research output: Contribution to journal › Article › peer-review

  • benzonitrile 100%
  • Serotonin Plasma Membrane Transport Proteins 69%
  • N-Methyl-3,4-methylenedioxyamphetamine 42%
  • Ligands 39%
  • Serotonin 33%
  100 Scopus citations

• Radiosynthesis and mouse brain distribution studies of [¹¹C] CP-126,998: A PET ligand for In vivo study of acetylcholinesterase

  Musachio, J. L., Flesher, J. E., Scheffel, U. A., Rauseo, P., Hilton, J., Mathews, W. B., Ravert, H. T., Dannals, R. F. & James Frost, J., 2002, In: Nuclear Medicine and Biology. 29, 5, p. 547-552 6 p.

  Research output: Contribution to journal › Article › peer-review

  • CP 126,998 100%
  • Acetylcholinesterase 44%
  • 5,7-dihydro-3-(2-(1-(phenylmethyl)-4-piperidinyl)ethyl)-6H-pyrrolo(3,2-f)-1,2-benzisoxazol-6-one 31%
  • Cholinesterase Inhibitors 30%
  • Ligands 28%
  20 Scopus citations

• Radiosynthesis of [¹¹C]paclitaxel

  Ravert, H. T., Klecker, R. W., Collins, J. M., Mathews, W. B., Pomper, M. G., Wahl, R. L. & Dannals, R. F., 2002, In: Journal of Labelled Compounds and Radiopharmaceuticals. 45, 6, p. 471-477 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Paclitaxel 100%
  • benzoyl chloride 83%
  • Benzoyl Chloride 51%
  • Radiochemical Yield 49%
  • Amines 43%
  21 Scopus citations
• 2001

  In vivo labeling of endothelin receptors with [¹¹C]L-753,037: Studies in mice and a dog

  Aleksic, S., Szabo, Z., Scheffel, U., Ravert, H. T., Mathews, W. B., Kerenyi, L., Rauseo, P. A., Gibson, R. E., Burns, H. D. & Dannals, R. F., 2001, In: Journal of Nuclear Medicine. 42, 8, p. 1274-1280 7 p.

  Research output: Contribution to journal › Article › peer-review

  • J 104132 100%
  • Endothelin Receptors 61%
  • Dogs 32%
  • Heart 29%
  • Injections 17%
  21 Scopus citations