Ann Lawler

2010

Increased male reproductive success in Ts65Dn "down syndrome" mice

Moore, C. S., Hawkins, C., Franca, A., Lawler, A., Devenney, B., Das, I. & Reeves, R. H., Dec 2010, In: Mammalian Genome. 21, 11-12, p. 543-549 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

2007

Bovine apolipoprotein B-100 is a dominant immunogen in therapeutic cell populations cultured in fetal calf serum in mice and humans

Sakamoto, N., Tsuji, K., Muul, L. M., Lawler, A. M., Petricoin, E. F., Candotti, F., Metcalf, J. A., Tavel, J. A., Lane, H. C., Urba, W. J., Fox, B. A., Varki, A., Lunney, J. K. & Rosenberg, A. S., Jul 15 2007, In: Blood. 110, 2, p. 501-508 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

39 Scopus citations

2006

Perinatal loss of Ts65Dn Down syndrome mice

Roper, R. J., St. John, H. K., Philip, J., Lawler, A. & Reeves, R. H., Jan 2006, In: Genetics. 172, 1, p. 437-443 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

51 Scopus citations

2004

Failure to degrade poly(ADP-ribose) causes increased sensitivity to cytotoxicity and early embryonic lethality

Koh, D. W., Lawler, A. M., Poitras, M. F., Sasaki, M., Wattler, S., Nehls, M. C., Stöger, T., Poirier, G. G., Dawson, V. L. & Dawson, T. M., Dec 21 2004, In: Proceedings of the National Academy of Sciences of the United States of America. 101, 51, p. 17699-17704 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

248 Scopus citations

2002

Craniofacial abnormalities resulting from targeted disruption of the murine Sim2 gene

Shamblott, M. J., Bugg, E. M., Lawler, A. M. & Gearhart, J. D., 2002, In: Developmental Dynamics. 224, 4, p. 373-380 8 p.

Research output: Contribution to journal › Article › peer-review

39 Scopus citations

2001

Rent1, a trans-effector of nonsense-mediated mRNA decay, is essential for mammalian embryonic viability

Medghalchi, S. M., Frischmeyer, P. A., Mendell, J. T., Kelly, A. G., Lawler, A. M. & Dietz, H. C., Jan 15 2001, In: Human molecular genetics. 10, 2, p. 99-105 7 p.

Research output: Contribution to journal › Article › peer-review

210 Scopus citations

2000

Regulation of left-right patterning in mice by growth/differentiation factor-1

Rankin, C. T., Bunton, T., Lawler, A. M. & Lee, S. J., Mar 2000, In: Nature genetics. 24, 3, p. 262-265 4 p.

Research output: Contribution to journal › Article › peer-review

175 Scopus citations

1999

Characterization of GDF-10 expression patterns and null mice

Zhao, R., Lawler, A. M. & Lee, S. J., Aug 1 1999, In: Developmental biology. 212, 1, p. 68-79 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

66 Scopus citations

Growth retardation and neonatal lethality in mice with a homozygous deletion in the C-terminal domain of RNA polymerase II

Litingtung, Y., Lawler, A. M., Sebald, S. M., Lee, E., Gearhart, J. D., Westphal, H. & Corden, J. L., 1999, In: Molecular and General Genetics. 261, 1, p. 100-105 6 p.

Research output: Contribution to journal › Article › peer-review

40 Scopus citations

Human X inactivation center induces random X chromosome inactivation in male transgenic mice

Migeon, B. R., Kazi, E., Haisley-Royster, C., Hu, J., Reeves, R., Call, L., Lawler, A., Moore, C. S., Morrison, H. & Jeppesen, P., Jul 15 1999, In: Genomics. 59, 2, p. 113-121 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

47 Scopus citations

Mutually exclusive expression of human red and green visual pigment-reporter transgenes occurs at high frequency in marine cone photoreceptors

Wang, Y., Smallwood, P. M., Cowan, M., Blesh, D., Lawler, A. & Nathans, J., Apr 27 1999, In: Proceedings of the National Academy of Sciences of the United States of America. 96, 9, p. 5251-5256 6 p.

Research output: Contribution to journal › Article › peer-review

78 Scopus citations

Regulation of anterior/posterior patterning of the axial skeleton by growth/differentiation factor 11

McPherron, A. C., Lawler, A. M. & Lee, S. J., Jul 1999, In: Nature genetics. 22, 3, p. 260-264 5 p.

Research output: Contribution to journal › Article › peer-review

330 Scopus citations

1998

CD34 expression by embryonic hematopoietic and endothelial cells does not require c-MYB

Krause, D. S., Mucenski, M. L., Lawler, A. M. & May, W. S., 1998, In: Experimental Hematology. 26, 11, p. 1086-1092 7 p.

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Cellular and developmental control of O₂ homeostasis by hypoxia- inducible factor 1α

Iyer, N. V., Kotch, L. E., Agani, F., Leung, S. W., Laughner, E., Wenger, R. H., Gassmann, M., Gearhart, J. D., Lawler, A. M., Yu, A. Y. & Semenza, G. L., Jan 15 1998, In: Genes and Development. 12, 2, p. 149-162 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1905 Scopus citations

1997

Altered metabolism of familial Alzheimer's disease linked amyloid precursor protein variants in yeast artificial chromosome transgenic mice

Lamb, B. T., Call, L. M., Slunt, H. H., Bardel, K. A., Lawler, A. M., Eckman, C. B., Younkin, S. G., Holtz, G., Wagner, S. L., Price, D. L., Sisodia, S. S. & Gearhart, J. D., Sep 1997, In: Human molecular genetics. 6, 9, p. 1535-1541 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

103 Scopus citations

A mouse model for X-linked adrenoleukodystrophy

Lu, J. F., Lawler, A. M., Watkins, P. A., Powers, J. M., Moser, A. B., Moser, H. W. & Smith, K. D., Aug 19 1997, In: Proceedings of the National Academy of Sciences of the United States of America. 94, 17, p. 9366-9371 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

202 Scopus citations

Regulation of skeletal muscle mass in mice by a new TGF-β superfamily member

McPherron, A. C., Lawler, A. M. & Lee, S. J., May 1 1997, In: Nature. 387, 6628, p. 83-90 8 p.

Research output: Contribution to journal › Article › peer-review

2864 Scopus citations

Targeted disruption of Gnas in embryonic stem cells

Schwindinger, W. F., Reese, K. J., Lawler, A. M., Gearhart, J. D. & Levine, M. A., 1997, In: Endocrinology. 138, 10, p. 4058-4063 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

15 Scopus citations

1996

Further characterization of factor VIII-deficient mice created by gene targeting: RNA and protein studies

Bi, L., Sarkar, R., Naas, T., Lawler, A. M., Pain, J., Shumaker, S. L., Bedian, V. & Kazazian, H. H., Nov 1 1996, In: Blood. 88, 9, p. 3446-3450 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

153 Scopus citations

Induction of murine acquired immunodeficiency syndrome (MAIDS) in allophenic mice generated from strains susceptible and resistant to disease

Sechler, J. M. G., Lawler, A., Hartley, J. W., Morse, H. C., McCarty, T. C., Swofford, R. & Rosenberg, A. S., Dec 1 1996, In: Journal of Experimental Medicine. 184, 6, p. 2101-2108 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Production and characterization of a mouse model of gyrate atrophy of the choroid and retina

Wang, T., Milam, A. H., Lawler, A., Steel, G. & Valle, D., Feb 15 1996, In: Investigative Ophthalmology and Visual Science. 37, 3, p. S1044

Research output: Contribution to journal › Article › peer-review

1995

Mice lacking ornithine–δ–amino–transferase have paradoxical neonatal hypoornithinaemia and retinal degeneration

Wang, T., Lawler, A. M., Steel, G., Sipila, I., Milam, A. H. & Valle, D., Oct 1995, In: Nature genetics. 11, 2, p. 185-190 6 p.

Research output: Contribution to journal › Article › peer-review

87 Scopus citations

Targeted disruption of the mouse factor VIII gene produces a model of haemophilia A

Bi, L., Lawler, A. M., Antonarakis, S. E., High, K. A., Gearhart, J. D. & Kazazian, H. H., May 1995, In: Nature genetics. 10, 1, p. 119-121 3 p.

Research output: Contribution to journal › Article › peer-review

489 Scopus citations

1993

Introduction and expression of the 400 kilobase precursor amyloid protein gene in transgenic mice

Lamb, B. T., Sisodia, S. S., Lawler, A. M., Slunt, H. H., Kitt, C. A., Kearns, W. G., Pearson, P. L., Price, D. L. & Gearhart, J. D., Sep 1993, In: Nature genetics. 5, 1, p. 22-30 9 p.

Research output: Contribution to journal › Article › peer-review

268 Scopus citations

1992

Linkage of two pseudogenes from V_κ1 and V_κ9 murine immunoglobulin families

Lawler, A. M., Umar, A. & Gearhart, P. J., Mar 1992, In: Molecular Immunology. 29, 3, p. 295-301 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

1989

Early rearrangements of genes encoding murine immunoglobulin kappa chains, unlike genes encoding heavy chains, use variable gene segments dispersed throughout the locus.

Lawler, A. M., Kearney, J. F., Kuehl, M. & Gearhart, P. J., 1989, In: Proceedings of the National Academy of Sciences of the United States of America. 86, 17, p. 6744-6747 4 p.

Research output: Contribution to journal › Article › peer-review

Open Access

55 Scopus citations

1988

Generation of Antibody Diversity Before and After Immunization

GEARHART, PATRICIA. J., LAWLER, ANN. M., LEVY, NINA. S., LEBECQUE, SERGE. G. & MALIPIERO, URSULA. V., Dec 1988, In: Annals of the New York Academy of Sciences. 546, 1, p. 57-62 6 p.

Research output: Contribution to journal › Article › peer-review

1 Scopus citations